CAS No.: 153653-30-6
Dofequidar fumarate Catalog No. CSN17917
Synonyms: MS-209
Dofequidar fumarate, an orally active quinoline compound, has been reported to overcome MDR by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00004886 Unspecified Adult Solid Tumor,... more >> Protocol Specific Collapse << Phase 1 Completed - France ... more >> Centre Oscar Lambret Lille, France, 59020 Institut Curie - Section Medicale Paris, France, 75248 Germany Haemato-Onkologische Praxis und Tagesklinik Munich (Muenchen), Germany, D-80639 Collapse << - 参考文献
- [1] Katayama R, Koike S, et al. Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export. Cancer Sci. 2009 Nov;100(11):2060-8.
- [2] Nakanishi O, Baba M, et al. Potentiation of the antitumor activity by a novel quinoline compound, MS-209, in multidrug-resistant solid tumor cell lines. Oncol Res. 1997;9(2):61-9.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 153653-30-6 | 储存条件 |
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| 分子式 | C34H35N3O7 | 运输 | 蓝冰 | |
| 分子量 | 597.66 | 别名 | MS-209 |
