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CAS No.: 309-29-5

Doxapram/多沙普仑 Catalog No. CSN10860

Synonyms: AHR-619;Brand name Dopram;Stimulex or Respiram

Doxapram inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.

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400-920-2911

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技术信息

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描述Doxapram inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01022151	Anaesthesia	Phase 2	Completed	-	Saudi Arabia ... more >> King Faisal University Khobar, Eastern, Saudi Arabia, 31952 Collapse <<
NCT01344317	-	-	Unknown	June 2016	Austria ... more >> Medical University of Vienna, Department of Pediatrics and Adolescent Medicine, Neonatology Vienna, Austria, 1090 Medical University of Vienna Vienna, Austria, 1090 Collapse <<
NCT02421068	-	-	Completed	-	Netherlands ... more >> MUMC Maastricht, Netherlands, 6229 HX Radboud UMC Nijmegen, Netherlands, 6525 GA Erasmus MC - Sophia Children's Hospital Rotterdam, Netherlands, 3015 CN Maxima Medical Center Veldhoven, Netherlands, 5504 DB Collapse <<

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参考文献

[1] Cotten JF, Keshavaprasad B, et al. The ventilatory stimulant doxapram inhibits TASK tandem pore (K2P) potassium channel function but does not affect minimum alveolar anesthetic concentration. Anesth Analg. 2006 Mar;102(3):779-85.
[2] Anderson-Beck R, Wilson L, et al. Doxapram stimulates dopamine release from the intact rat carotid body in vitro. Neurosci Lett. 1995 Feb 24;187(1):25-8.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.6420 mL
- 13.2098 mL
- 26.4196 mL
- 5 mM
- 0.5284 mL
- 2.6420 mL
- 5.2839 mL
- 10 mM
- 0.2642 mL
- 1.3210 mL
- 2.6420 mL

技术信息

CAS号	309-29-5	储存条件	粉末 Sealed in dry,2-8°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C24H30N2O2	运输	蓝冰
分子量	378.51	别名	AHR-619;Brand name Dopram;Stimulex or Respiram;多沙普仑

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT01022151	Anaesthesia	Phase 2	Completed	-	Saudi Arabia ... more >> King Faisal University Khobar, Eastern, Saudi Arabia, 31952 Collapse <<
NCT01344317	-	-	Unknown	June 2016	Austria ... more >> Medical University of Vienna, Department of Pediatrics and Adolescent Medicine, Neonatology Vienna, Austria, 1090 Medical University of Vienna Vienna, Austria, 1090 Collapse <<
NCT02421068	-	-	Completed	-	Netherlands ... more >> MUMC Maastricht, Netherlands, 6229 HX Radboud UMC Nijmegen, Netherlands, 6525 GA Erasmus MC - Sophia Children's Hospital Rotterdam, Netherlands, 3015 CN Maxima Medical Center Veldhoven, Netherlands, 5504 DB Collapse <<
NCT00477451	Treatment of Induced Panic Att... more >>ack Collapse <<	Phase 2	Completed	-	United States, New York ... more >> SUNY Downstate Medical Center Brooklyn, New York, United States, 11203-2056 New York State Psychiatric Institute New York, New York, United States, 10021 Mt. Sinai School Of Medicine New York, New York, United States, 10029 Collapse <<
NCT02820025	Anesthesia	Not Applicable	Active, not recruiting	December 2017	China, Ningxia ... more >> Anesthesiology department of General Hospital of Ningxia Medical University Yinchuan, Ningxia, China, 750004 Collapse <<
NCT00477451	-	-	Completed	-	-
NCT02171910	Sedation Hypo... more >>xia Collapse <<	Phase 4	Completed	-	Finland ... more >> Helsinki University Central Hospital Helsinki, Uusimaa, Finland, 00029 HUS Collapse <<
NCT00389909	Premature Infants ... more >> Apnea Collapse <<	Phase 4	Completed	-	France ... more >> Maternite Regionale Universitaire Nancy, France, 54042 Hopital des Enfants Toulouse, France, 31059 Collapse <<

Doxapram/多沙普仑 Catalog No. CSN10860

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