|1-(2-((4-氯苄基)氧基)-2-(2,4-二氯苯基)乙基)-1H-咪唑硝酸盐|CsnPharm

CAS No.: 24169-02-6

Econazole nitrate/硝酸益康唑 Catalog No. CSN16732

Synonyms: NSC 243115;Econazole (nitrate);SQ 13,020

Econazole nitrate is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Econazole Nitrate is an imidazole class antifungal medication. Vaginal candidiasis in rats was cured after oral administration of econazole. Toxicity and teratogenicity studies in different laboratory animals indicate that econazole is well tolerated^[3]. Econazole nitrate loaded transethosomes are effective to deliver econazole nitrate transdermally in a controlled fashion for effective elimination of cutaneous candidiasis^[4]. In acidic solutions ECN/αCD (Econazole Nitrate/α-cyclodextrin) can enhance the antifungal activity to filamentous fungi^[5]. Reductions in VAS (visual analog scale) scores of econazole nitrate topical foam were significantly greater than those of ketoconazole cream, indicating the superiority of the econazole nitrate foam in reducing pruritus^[6].
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT02713893	Healthy	Phase 1	Completed	-	Switzerland ... more >> CROSS Research S.A., Phase I Unit Arzo, Switzerland, CH-6864 Collapse <<
NCT00768599	Tinea Pedis A... more >>thlete's Foot Collapse <<	Phase 2	Completed	-	United States, California ... more >> Stacy Smith, MD San Diego, California, United States, 92123 United States, Michigan Daniel Stewart, DO Clinton Township, Michigan, United States, 48038 United States, Minnesota Steven Kempers, MD Fridley, Minnesota, United States, 55432 United States, Tennessee Michael Gold, MD Nashville, Tennessee, United States, 37215 United States, Texas Michael Jarratt, MD Austin, Texas, United States, 78759 United States, Utah Leonard Swinyer, MD Salt Lake City, Utah, United States, 84124 Collapse <<
NCT03129321	-	-	Completed	-	-

更多
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.2487 mL
- 11.2436 mL
- 22.4873 mL
- 5 mM
- 0.4497 mL
- 2.2487 mL
- 4.4975 mL
- 10 mM
- 0.2249 mL
- 1.1244 mL
- 2.2487 mL

技术信息

CAS号

24169-02-6

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C18H16Cl3N3O4

运输

蓝冰

分子量

444.70

别名

NSC 243115;Econazole (nitrate);SQ 13,020;Econazole Nitrate;R 14,827;R 14827;Spectazole;SQ-13050;Ecoza;epi-Pevaryl;Gyno-pevaryl;Ifenec;硝酸益康唑;益康唑硝酸盐

溶解度

DMSO	400.0 mg/mL (899.5 mM)
Water	insoluble

动物实验配方

IP	2% DMSO+2% Tween80+40% PEG300+water	8 mg/mL	clear
PO	0.5% CMC-Na	31 mg/mL	suspension

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT02713893	Healthy	Phase 1	Completed	-	Switzerland ... more >> CROSS Research S.A., Phase I Unit Arzo, Switzerland, CH-6864 Collapse <<
NCT00768599	Tinea Pedis A... more >>thlete's Foot Collapse <<	Phase 2	Completed	-	United States, California ... more >> Stacy Smith, MD San Diego, California, United States, 92123 United States, Michigan Daniel Stewart, DO Clinton Township, Michigan, United States, 48038 United States, Minnesota Steven Kempers, MD Fridley, Minnesota, United States, 55432 United States, Tennessee Michael Gold, MD Nashville, Tennessee, United States, 37215 United States, Texas Michael Jarratt, MD Austin, Texas, United States, 78759 United States, Utah Leonard Swinyer, MD Salt Lake City, Utah, United States, 84124 Collapse <<
NCT03129321	-	-	Completed	-	-
NCT03129321	Tinea Pedis	Phase 3	Completed	-	-
NCT02720783	Healthy Women	Phase 1	Completed	-	Switzerland ... more >> CROSS Research S.A., Phase I Unit Arzo, Switzerland, CH-6864 Collapse <<
NCT00768599	-	-	Completed	-	-
NCT01696799	Interdigital Tinea Pedis	Phase 2	Completed	-	United States, California ... more >> Therapeutics Inc. San Diego, California, United States, 92123 Collapse <<
NCT01353976	Tinea Pedis A... more >>thlete's Foot Collapse <<	Phase 3	Completed	-	United States, Florida ... more >> Francisco Flores, MD Miramar, Florida, United States, 33027 United States, Michigan Daniel M. Stewart, DO Clinton Township, Michigan, United States, 48038 United States, Nevada Cyaandi Dove, DPM Las Vegas, Nevada, United States, 89119 United States, Ohio Robert S. Haber, MD South Euclid, Ohio, United States, 44118 United States, South Carolina Cynthia Strout, MD Mt. Pleasant, South Carolina, United States, 29464 United States, Tennessee Michael H. Gold, MD Nashville, Tennessee, United States, 37215 United States, Texas Jeffrey Adelglass, MD Plano, Texas, United States, 75234 Collapse <<
NCT01358240	Tinea Pedis A... more >>thlete's Foot Collapse <<	Phase 3	Completed	-	United States, California ... more >> Sunil S. Dhawan, MD Fremont, California, United States, 94538 United States, Delaware Guy F. Webster, MD, PhD Hockessin, Delaware, United States, 19707 United States, Florida Marta I. Rendon, MD Boca Raton, Florida, United States, 33486 Jonathan Kantor, MD Jacksonville, Florida, United States, 32204 United States, Minnesota Steven E. Kempers, MD Fridley, Minnesota, United States, 55432 United States, Nebraska Joel Schlessinger, MD Omaha, Nebraska, United States, 68144 United States, Oregon Phoebe Rich, MD Portland, Oregon, United States, 97210 United States, Tennessee Edward J. Primka III, MD Knoxville, Tennessee, United States, 37917 United States, Texas Michael T. Jarratt, MD Austin, Texas, United States, 78759 William Abramovits, MD Dallas, Texas, United States, 75230 United States, Virginia David M. Pariser, MD, FAAD, FACP Norfolk, Virginia, United States, 23507 United States, Wisconsin Harry H. Sharata, MD, PhD Madison, Wisconsin, United States, 53719 Collapse <<
NCT01353976	-	-	Completed	-	-

Econazole nitrate/硝酸益康唑 Catalog No. CSN16732

靶点选择性

请登录您的专属账户

确认信息