CAS No.: 1210945-69-9
EG00229 Catalog No. CSN17568
Synonyms: EG 00229 (trifluoroacetate salt)
EG00229 is the first small molecule inhibitor of the neuropilin-1 and VEGF-A interaction with an IC50 of inhibition of 8 μM(125I-VEGF binding to PAE/NRP1 cells).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Nissen JC, Selwood DL, et al. Tuftsin signals through its receptor neuropilin-1 via the transforming growth factor beta pathway. J Neurochem. 2013 Nov;127(3):394-402.
- [2] Jarvis A, Allerston CK, et al. Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. J Med Chem. 2010 Mar 11;53(5):2215-26.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1210945-69-9 | 储存条件 |
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| 分子式 | C19H20F3N7O7S3 | 运输 | 蓝冰 | |
| 分子量 | 611.60 | 别名 | EG 00229 (trifluoroacetate salt) |
