CAS No.: 1154-25-2
EIPA Catalog No. CSN25462
Synonyms: L593754;MH 12-43;5-(N-ethyl-N-isopropyl)-Amiloride
EIPA (L593754) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 参考文献
- [1] Dai XQ, et al. Inhibition of TRPP3 channel by MK-870 and analogs. Mol Pharmacol. 2007 Dec;72(6):1576-85.
- [2] Shi H, et al. Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells. Cell Physiol Biochem. 2017;42(6):2418-2429.
- [3] Zhu BY, et al. A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1154-25-2 | 储存条件 |
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| 分子式 | C11H18ClN7O | 运输 | 蓝冰 | |||
| 分子量 | 299.76 | 别名 | L593754;MH 12-43;5-(N-ethyl-N-isopropyl)-Amiloride;L-593,754;Ethylisopropylamiloride | |||
| 溶解度 |
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动物实验配方 |
