CAS No.: 1448754-43-5
Eleclazine HCl Catalog No. CSN19026
Synonyms: GS 6615 hydrochloride;GS 6615 HCl;Eleclazine Hydrochloride
Eleclazine HCl is a late Na+ current inhibitor with IC50 value of 0.7 μM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Rajamani S, Liu G, et al. The novel late Na(+) current inhibitor, GS-6615 (eleclazine) and its anti-arrhythmic effects in rabbit isolated heart preparations. Br J Pharmacol. 2016 Nov;173(21):3088-3098.
- [2] Justo F, Fuller H, et al. Inhibition of the cardiac late sodium current with eleclazine protects against ischemia-induced vulnerability to atrial fibrillation and reduces atrial and ventricular repolarization abnormalities in the absence and presence of concurrent adrenergic stimulation. Heart Rhythm. 2016 Sep;13(9):1860-7.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1448754-43-5 | 储存条件 |
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| 分子式 | C21H17ClF3N3O3 | 运输 | 蓝冰 | |||
| 分子量 | 451.83 | 别名 | GS 6615 hydrochloride;GS 6615 HCl;Eleclazine Hydrochloride;Eleclazine HCl;GS-6615 | |||
| 溶解度 |
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动物实验配方 |
