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CAS No.: 928659-70-5

Eliglustat hemitartrate/依利格鲁司他半酒石酸盐 Catalog No. CSN16862

Synonyms: Genz-112638;Eliglustat tartrate;Genz-112638 Tartrate

Eliglustat tartrate, a specific inhibitor of glucosylceramide synthase, is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1).

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描述Eliglustat tartrate, a specific inhibitor of glucosylceramide synthase, is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1).
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01659944	Healthy	Phase 1	Completed	-	United States, Texas ... more >> Austin, Texas, United States Collapse <<
NCT01357811	Healthy Volunteer	Phase 1	Completed	-	United States, Texas ... more >> PPD Phase I Clinic Austin, Texas, United States Collapse <<
NCT02536937	Gaucher Disease	Phase 1	Completed	-	United States, Florida ... more >> Investigational Site Number 840004 Miami, Florida, United States, 33014 United States, Minnesota Investigational Site Number 840002 St. Paul, Minnesota, United States, 55144 United States, Tennessee Investigational Site Number 840001 Knoxville, Tennessee, United States, 37920 Collapse <<

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.0426 mL
- 5.2128 mL
- 10.4257 mL
- 5 mM
- 0.2085 mL
- 1.0426 mL
- 2.0851 mL
- 10 mM
- 0.1043 mL
- 0.5213 mL
- 1.0426 mL

技术信息

CAS号	928659-70-5	储存条件	粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C50H78N4O14	运输	蓝冰
分子量	959.17	别名	Genz-112638;Eliglustat tartrate;Genz-112638 Tartrate;Eliglustat (hemitartrate);Brand name Cerdelga

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT01659944	Healthy	Phase 1	Completed	-	United States, Texas ... more >> Austin, Texas, United States Collapse <<
NCT01357811	Healthy Volunteer	Phase 1	Completed	-	United States, Texas ... more >> PPD Phase I Clinic Austin, Texas, United States Collapse <<
NCT02536937	Gaucher Disease	Phase 1	Completed	-	United States, Florida ... more >> Investigational Site Number 840004 Miami, Florida, United States, 33014 United States, Minnesota Investigational Site Number 840002 St. Paul, Minnesota, United States, 55144 United States, Tennessee Investigational Site Number 840001 Knoxville, Tennessee, United States, 37920 Collapse <<
NCT01074944	Gaucher Disease	Phase 3	Completed	-	-
NCT01452542	Healthy Volunteer	Phase 1	Completed	-	United States, Texas ... more >> PPD Phase 1 Unit Austin, Texas, United States Collapse <<
NCT01074944	-	-	Completed	-	-
NCT02536911	Gaucher Disease	Phase 1	Completed	-	United States, Florida ... more >> Investigational Site Number 840002 Miami, Florida, United States, 33014 United States, Tennessee Investigational Site Number 840001 Knoxville, Tennessee, United States, 37920 Collapse <<
NCT00891202	Gaucher Disease, Type 1	Phase 3	Completed	-	United States, California ... more >> UCSF MS Center San Francisco, California, United States, 94143 United States, Connecticut Yale University School of Medicine New Haven, Connecticut, United States, 06510 United States, Georgia Emory University Medical Genetics Decatur, Georgia, United States, 30033 United States, Kansas University of Kansas Medical Center, Division of Hematology/Oncology, Dept. of Medicine Westwood, Kansas, United States, 66160 United States, New York New York University School of Medicine, Neurology Department New York, New York, United States, 10016 Mount Sinai School of Medicine New York, New York, United States, 10029 Bulgaria University hospital "Alexandrovska" Sofia Sofia, Bulgaria, 1431 Canada Sir Mortimer B. Davis - Jewish General Hospital Montreal, Quebec, Canada, H3T 1E2 Mount Sinai Hospital and the Samuel Lunenfeld Research Institute Toronto Ontario, Canada, M5G 1X5 Colombia Hospital de San Jose Bogota, Colombia India Christian Medical College Hospital Vellore, India, 632004 Israel Rabin Medical Center, Beilinson Hospital Petach Tikvah, Israel, 49100 Lebanon Hôtel-Dieu de France University Hospital Beirut, Lebanon Mexico OCA Hospital Monterrey, Nuevo Leon, Mexico Russian Federation Hematology Research Center of Ministry of Healthcare of the Russian Federation Moscow, Russian Federation, 125167 Serbia Institut za endokrinologiju Belgrade, Serbia, 11000 Tunisia Hopital La-Rabta Tunis, TN, Tunisia, 1007 United Kingdom Royal Free Hospital London, United Kingdom, NW3 2QG Collapse <<
NCT00943111	-	-	Completed	-	-
NCT00358150	-	-	Completed	-	-
NCT00943111	Gaucher Disease, Type 1	Phase 3	Completed	-	-
NCT00358150	Gaucher Disease, Type 1 ... more >> Cerebroside Lipidosis Syndrome Glucocerebrosidase Deficiency Disease Glucosylceramide Beta-Glucosidase Deficiency Disease Gaucher Disease, Non-Neuronopathic Form Collapse <<	Phase 2	Completed	-	United States, New York ... more >> New York University New York, New York, United States New York, New York, United States Argentina Aprillus Asistencia e Investigación Buenos Aires, Argentina Hospital de Oncologia Maria Curie Buenos Aires, Argentina IMAI Buenos Aires, Argentina Instituto Argentino de Diagnostico y Tratamiento (IADT) Buenos Aires, Argentina Buenos Aires, Argentina Hospital Ramos Mejia Ciudad Autonoma de Buenos Aires, Argentina Israel Rambam Medical Center Haifa, Israel Haifa, Israel Sha'are Zedek Medical Centre Jerusalem, Israel Jerusalem, Israel Italy Universita degli Studi di Milano Milano, Italy Mexico Instituto Mexicano del Seguro Social D.f., Mexico Mexico City, Mexico Russian Federation Hematology Research Center of Ministry of Healthcare of the Russian Federation Moscow, Russian Federation Moscow, Russian Federation Collapse <<
NCT00891202	-	-	Completed	-	-

Eliglustat hemitartrate/依利格鲁司他半酒石酸盐 Catalog No. CSN16862

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