|(1R,3aS,4R,6aS)-1,4-双(3,4-二甲氧基苯基)四氢-1H,3H-呋喃并[3,4-c]呋喃|CsnPharm

CAS No.: 526-06-7

Synonyms: (-)-Eudesmin;Eudesmine;(-)-Eudesmine

Eudesmin, a natural product isolated and purified from the dry leaves of Haplophyllum perforatum Kar.et Kir.

规格	价格	促销价格	库存	数量

400-920-2911

加入购物车大规格询价

产品咨询

400-920-2911

纯度 & 质量文件批次:

生物活性

描述Eudesmin, a natural product isolated and purified from the dry leaves of Haplophyllum perforatum Kar.et Kir. with antiinflammatory effects, can significantly inhibit TNF-alpha production by lipopolysaccharide (LPS)-stimulated murine macrophage RAW264.7 without displaying cytotoxicity, and can significantly attenuate T cell proliferation stimulated by concanavalin A (Con A) in a dose-dependent manner. Eudesmin can induce vascular relaxation in rat aorta, which is mediated by release of nitric oxide and prostanoid through the involvement of histamine receptor present in the endothelial cells, and can induce neurite outgrowth and enhance nerve growth factor (NGF)-mediated neurite outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways at a concentration of 50 mM, showing neuritogenic activity. Eudesmin also has significant anticonvulsant and sedative effects, and the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.
参考文献

实验方案

技术信息

CAS号	526-06-7	储存条件	粉末 Sealed in dry,Store in freezer, under -20°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C22H26O6	运输	蓝冰
分子量	386.44	别名	(-)-Eudesmin;Eudesmine;(-)-Eudesmine;桉脂素

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

请登录您的专属账户