CAS No.: 53155-25-2
Euscaphic acid/野鸦椿酸 Catalog No. CSN14493
Synonyms: Euscaphic Acid;野鸦椿酸
Euscaphic acid, a natural product isolated and purified from the dried fruit of Ziziphus jujuba, with anti-diabetic and anti-inflammatory activities, induces death by activation of caspase-3, dependent apoptotic pathway, and inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction to downregulate NF-κB activations.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Li JJ, Li Y, et al. Simultaneous determination of corosolic acid and euscaphic acid in the plasma of normal and diabetic rat after oral administration of extract of Potentilla discolor Bunge by high-performance liquid chromatography/electrospray ionization mass spectrometry. Biomed Chromatogr. 2014 May;28(5):717-24.
- [2] Kim IT, Ryu S, et al. Euscaphic acid isolated from roots of Rosa rugosa inhibits LPS-induced inflammatory responses via TLR4-mediated NF-κB inactivation in RAW 264.7 macrophages. J Cell Biochem. 2012 Jun;113(6):1936-46.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 53155-25-2 | 储存条件 |
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| 分子式 | C30H48O5 | 运输 | 蓝冰 | |
| 分子量 | 488.70 | 别名 | Euscaphic Acid;野鸦椿酸 |
