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CAS No.: 133514-43-9
Synonyms: Exendin (9-39);ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2;Exendin-3 (9-39) amide
Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT02050074 | Type 2 Diabetes | Phase 4 | Completed | - | Denmark ... more >> Diabetes Research Division, Department of Medicine, Gentofte Hospital Hellerup, Copenhagen, Denmark, 2900 Collapse << |
NCT01363609 | Obesity Type ... more >>2 Diabetes Collapse << | Not Applicable | Completed | - | Netherlands ... more >> VU University Medical Center Amsterdam, Netherlands, 1081 HV Collapse << |
NCT03101930 | Obesity PreDi... more >>abetes Collapse << | Phase 4 | Recruiting | September 1, 2021 | United States, Tennessee ... more >> Vanderbilt University Medical Center Recruiting Nashville, Tennessee, United States, 37232 Contact: Dustin Mayfield, RN 615-343-8701 Contact: Nancy J Brown, MD 6153438701 nancy.j.brown@vanderbilt.edu Collapse << |
实验方案
技术信息
CAS号 | 133514-43-9 | 储存条件 |
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分子式 | C149H234N40O47S | 运输 | 蓝冰 | |||
分子量 | 3369.76 | 别名 | Exendin (9-39);ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2;Exendin-3 (9-39) amide;Exendin 9-39;埃森汀 9-39 | |||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT02050074 | Type 2 Diabetes | Phase 4 | Completed | - | Denmark ... more >> Diabetes Research Division, Department of Medicine, Gentofte Hospital Hellerup, Copenhagen, Denmark, 2900 Collapse << |
NCT01363609 | Obesity Type ... more >>2 Diabetes Collapse << | Not Applicable | Completed | - | Netherlands ... more >> VU University Medical Center Amsterdam, Netherlands, 1081 HV Collapse << |
NCT03101930 | Obesity PreDi... more >>abetes Collapse << | Phase 4 | Recruiting | September 1, 2021 | United States, Tennessee ... more >> Vanderbilt University Medical Center Recruiting Nashville, Tennessee, United States, 37232 Contact: Dustin Mayfield, RN 615-343-8701 Contact: Nancy J Brown, MD 6153438701 nancy.j.brown@vanderbilt.edu Collapse << |
NCT01918566 | Exploratory Behavior | Not Applicable | Completed | - | Switzerland ... more >> University Hospital Basel, Switzerland, CH-4031 Collapse << |
NCT03739268 | Type 2 Diabetes Mellitus | Not Applicable | Recruiting | September 1, 2020 | Denmark ... more >> Steno Diabetes Center Copenhagen, Gentofte Hospital Recruiting Hellerup, Denmark, 2900 Contact: Henriette H Nerild, M.D. +45 3867 4264 henriette.holst.nerild@regionh.dk Collapse << |
NCT01181986 | - | - | Completed | - | - |
NCT01701973 | Obesity | Phase 4 | Completed | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Collapse << |
NCT01701973 | - | - | Completed | - | - |
NCT01181986 | Type 2 Diabetes Mellitus | Phase 4 | Completed | - | United States, Arizona ... more >> Phoenix VA Medical Center Phoenix, Arizona, United States, 85012 Collapse << |
NCT02746757 | Healthy Volunteers | Not Applicable | Completed | - | Sweden ... more >> Karolinska Institutet, Karolinska University Hospital Stockholm, Sweden, 17176 Collapse << |
NCT01449019 | Diabetes Mellitus, Type 2 | Phase 1 | Completed | - | Germany ... more >> Ludwig Maximilians-University, Clinical Research Unit Munich, Germany, 80999 Clinical Research unit, Dept. of Internal Medicine II - Großhadern, University of Munich Munich, Germany, 81377 Collapse << |
NCT01579981 | Type 2 Diabetes | Not Applicable | Completed | - | Denmark ... more >> Dept. of Endocrinology, Hvidovre Hospital Hvidovre, Denmark, DK-2650 Collapse << |
NCT01865760 | Obesity Hypog... more >>lycemia Surgery Collapse << | Not Applicable | Unknown | March 2016 | Denmark ... more >> Department of Endocrinology, Aarhus University Hospital Recruiting Aarhus C, Denmark, 8000 Contact: Joan Bach Nielsen, Dr 0045+24818454 joanni@rm.dk Sub-Investigator: Joan Bach Nielsen, MD Collapse << |
NCT01760772 | Heart Disease | Not Applicable | Unknown | February 2015 | United States, Ohio ... more >> Veteran's Affairs Clinical Research Unit Not yet recruiting Cincinnati, Ohio, United States, 45220 Contact: Michelle R Adams, PhD 513-558-6920 michelle.adams@uc.edu Principal Investigator: Michelle R Adams, PhD Principal Investigator: David D'Alessio, MD Collapse << |
NCT03241303 | Glucose Metabolism Disorders | Not Applicable | Recruiting | July 1, 2018 | Denmark ... more >> Center for Diabetesresearch Recruiting Hellerup, Denmark, 2900 Contact: Filip K Knop, MD, PhD 26830161 Filipknop@dadlnet.dk Collapse << |
NCT00992901 | Post Bariatricsurgery ... more >> Hypoglycemia Collapse << | Early Phase 1 | Recruiting | July 2020 | United States, Texas ... more >> South Texas Veterans Health Care System Recruiting San Antonio, Texas, United States, 78229 Contact: Marzieh Salehi 210-567-6691 salehi@uthscsa.edu Contact: Andrea Hansis-Diarte 210-567-6691 hansisdiarte@uthscsa.edu Principal Investigator: Marzieh Salehi, MD, MS Collapse << |
NCT03246451 | Glucose Metabolism Disorders | Not Applicable | Completed | - | Denmark ... more >> Center for Diabetes Research Gentofte, Copenhagen, Denmark, 2900 Collapse << |
NCT01281228 | Diabetes Mellitus ... more >> Diabetes Mellitus, Type 2 Obesity Collapse << | Not Applicable | Completed | - | Netherlands ... more >> VU University Medical Center Amsterdam, De Boelelaan 1117, Netherlands, 1007MB Collapse << |
NCT00551590 | Type 2 Diabetes Mellitus | Phase 1 | Completed | - | Germany ... more >> Clinical Research unit, Dept. of Internal Medicine II - Großhadern, University of Munich Munich, Germany, 81377 Collapse << |
NCT03013296 | Glucose Metabolism Disorders | Not Applicable | Completed | - | Denmark ... more >> Center for Diabetes Research Copenhagen, Gentofte, Denmark, 2900 Collapse << |
NCT01795144 | Monogenic Diabetes | Phase 1 | Completed | - | United States, Illinois ... more >> University of Chicago Chicago, Illinois, United States, 60637 Collapse << |
NCT02287285 | Type 2 Diabetes Mellitus | Early Phase 1 | Active, not recruiting | October 2018 | United States, New York ... more >> New York Obesity Research Center, Columbia University New York, New York, United States, 10032 Collapse << |
NCT01729299 | Diabetes | Not Applicable | Unknown | April 2014 | United States, Ohio ... more >> University of Cincinnati Recruiting Cincinnati, Ohio, United States, 45267 Contact: Jenny Tong, MD, MPH 513-558-4446 jenny.tong@uc.edu Contact: Ahrar Haque, MD 513-558-3923 haqueau@uc.edu Principal Investigator: Jenny Tong, MD, MPH Cincinnati Children's Hospital and Medical Center Recruiting Cincinnati, Ohio, United States Contact: Ahrar Haque, MD 513-558-3923 Collapse << |
NCT02971631 | Gastric Cancer ... more >> Dumping Syndrome Collapse << | Not Applicable | Enrolling by invitation | December 2018 | United Kingdom ... more >> Cambridge University Hospitals NHS Foundation Trust Cambridge, Cambridgeshire, United Kingdom, CB2 0QQ Collapse << |
NCT03133741 | Glucose Metabolism Disorders | Not Applicable | Completed | - | Denmark ... more >> Center for Diabetes Research Gentofte, Copenhagen, Denmark, 2900 Collapse << |
NCT02697253 | Obesity | Phase 2 | Active, not recruiting | December 2020 | United States, New York ... more >> Columbia University Medical Center - Russ Berrie Building New York, New York, United States, 10032 Collapse << |
NCT02823665 | Post Bariatric Surgery ... more >> Gastric Bypass Sleeve Gastrectomy Hypoglycemia After Gastric Bypass Collapse << | Early Phase 1 | Recruiting | July 2022 | United States, Texas ... more >> South Texas Veterans Health Care System Recruiting San Antonio, Texas, United States, 78229 Contact: Andrea Hansis-Diarte 210-567-6691 hansisdiarte@uthscsa.edu Principal Investigator: Marzieh Salehi, MD Collapse << |
NCT02336659 | Severe Obesity | Not Applicable | Completed | - | Denmark ... more >> Hvidovre University Hospital Hvidovre, Denmark, DK-2650 Collapse << |
NCT01152333 | Appetite Regulation ... more >> Obesity Collapse << | Not Applicable | Withdrawn(This study is delaye... more >>d. It was not funded.) Collapse << | July 2016 | United States, Washington ... more >> University of Washington Seattle, Washington, United States, 98195 Collapse << |
NCT00980083 | Healthy Subjects ... more >> Gastric Emptying Collapse << | Phase 1 | Completed | - | Germany ... more >> Department of Internal Medicine II, University of Munich Munich, Germany, 81377 Collapse << |
NCT02844907 | Insulin Secretion | Phase 4 | Recruiting | December 2020 | United States, North Carolina ... more >> VA Health Care System Recruiting Durham, North Carolina, United States, 27705 Contact: Leslie S Kelly 910-782-9771 leslie.kelly@va.gov Contact: Lucy W Piner, MS 919-660-6781 lucy.piner@va.gov Principal Investigator: David D'Alessio, MD Collapse << |
NCT02170870 | Dyspepsia Dia... more >>betes Mellitus With Gastrointestinal Symptoms Collapse << | Phase 1 | Completed | - | United States, Minnesota ... more >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 Mayo Clinic Rochester, Minnesota, United States, 55905 Collapse << |
NCT01900340 | Appetite and General Nutrition... more >>al Disorders Collapse << | Phase 1 | Completed | - | Switzerland ... more >> University Hospital Basel, Phase 1 Research Unit Basel, Switzerland Collapse << |
NCT01803451 | Post-bariatric Surgery | Early Phase 1 | Recruiting | December 2020 | United States, Texas ... more >> South Texas Veterans Health Care System Recruiting San Antonio, Texas, United States, 78229 Contact: Marzieh Salehi, MD MS 210-567-6691 salehi@uthscsa.edu Contact: Andrea Hansis-Diarte 210-567-6691 HansisDiarte@uthscsa.edu Principal Investigator: Marzieh Salehi, MD Collapse << |
NCT02639130 | Type 2 Diabetes | Phase 4 | Completed | - | Germany ... more >> Diabeteszentrum Bad Lauterberg Bad Lauterberg, Niedersachsen, Germany, 37431 Collapse << |
NCT02550145 | Hypoglycemia | Phase 1 | Unknown | - | United States, California ... more >> Stanford University School of Medicine Recruiting Stanford, California, United States, 94305 Contact: Colleen Craig, M.D. 650-350-2153 cmcraig@stanford.edu Collapse << |
NCT01162499 | Postprandial Hypoglycemia | Not Applicable | Completed | - | United States, Pennsylvania ... more >> The Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT00393445 | Hyperglycemia | Phase 1 | Completed | - | Germany ... more >> Ludwig Maximilians University, Clinical Research Unit Munich, Germany, D-81377 Collapse << |
NCT02996812 | Hyperinsulinemia Hypoglycemia | Phase 1 | Unknown | May 2017 | United States, California ... more >> Stanford University School of Medicine Stanford, California, United States, 94305 Collapse << |
NCT01162499 | - | - | Completed | - | - |
NCT00468091 | Digestive Physiology ... more >> Gastrointestinal Motility Gastrointestinal Hormones Glucagon-like Peptide 1 Exendin (9-39) Collapse << | Phase 1 | Completed | - | Germany ... more >> Clinical Research unit, Dept. of Internal Medicine II - Großhadern, University of Munich Munich, Germany, 81377 Collapse << |
NCT00897676 | Congenital Hyperinsulinism | Phase 1 Phase 2 | Completed | - | United States, Pennsylvania ... more >> The Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT00571324 | Congenital Hyperinsulinism | Phase 1 Phase 2 | Completed | - | United States, Pennsylvania ... more >> The Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT00897676 | - | - | Completed | - | - |
NCT00571324 | - | - | Completed | - | - |
NCT02771574 | Post Bariatric Hypoglycemia | Phase 2 | Completed | - | United States, California ... more >> Stanford University School of Medicine Stanford, California, United States, 94305 Collapse << |
NCT00835328 | Congenital Hyperinsulinism | Phase 1 Phase 2 | Recruiting | December 2019 | United States, Pennsylvania ... more >> The Children's Hospital of Philadelphia Recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Stephanie Givler, BS,CCRC 267-426-7622 givler@email.chop.edu Principal Investigator: Diva D De Leon, MD Sub-Investigator: Charles A Stanley, MD Collapse << |
NCT03373435 | Postbariatric Hypoglycemia | Phase 2 | Recruiting | October 2018 | United States, California ... more >> Stanford University Recruiting Palo Alto, California, United States, 94304 Contact: Aileen Muno munoai@stanford.edu Contact: Marilyn Tan, MD mjtan@stanford.edu Principal Investigator: Marilyn Tan, MD United States, Colorado University of Colorado, Denver Recruiting Aurora, Colorado, United States, 80045 Contact: Helen Lawler, MD 720-848-5146 Endo.ClinicalTrials@ucdenver.edu United States, Maryland Johns Hopkins University Recruiting Baltimore, Maryland, United States, 21287 Contact: Dezeray Cephas 443-507-8222 dcephas1@jhu.edu Principal Investigator: Clare Lee, MD, MHS United States, North Carolina Duke Early Phase Clinical Research Recruiting Durham, North Carolina, United States, 27710 Contact 919-613-6246 DCRIvolunteer@duke.edu United States, Wisconsin University of Wisconsin Recruiting Madison, Wisconsin, United States, 53792 Contact: Constance B Trantow 608-265-7814 Collapse << |
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