CAS No.: 102676-47-1
Fadrozole/法倔唑 Catalog No. CSN10978
Synonyms: CGS 16949A free base;(Rac)-FAD286;CGS-16949A
Fadrozole is a selective aromatase inhibitor that has been introduced in Japan for the treatment of breast cancer.
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纯度 & 质量文件
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生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00247663 Postmenopausal Women With Adva... more >>nced Breast Cancer Collapse << Phase 2 Completed - Japan ... more >> Novartis Investigative Site Kashiwa, Chiba, Japan, 277-8577 Novartis Investigative Site Amagasaki, Hyogo, Japan, 660-8511 Novartis Investigative Site Hamamatsu, Shizuoka, Japan, 430-8558 Novartis Investigative Site Chuo-Ku, Tokyo, Japan, 104-0045 Novartis Investigative Site Cyuo-ku, Tokyo, Japan, 104-8560 Novartis Investigative Site Shinjuku-ku, Tokyo, Japan, 160-8582 Novartis Investigative Site Fukuoka, Japan, 811-4395 Novartis Investigative Site Kumamoto, Japan, 862-0909 Novartis Investigative Site Nigata, Japan, 951-8566 Novartis Investigative Site Saitama, Japan, 338-8553 Collapse << NCT03279289 Metastatic Colorectal Cancer Phase 2 Recruiting July 2021 Spain ... more >> Spanish Cooperative Group for Digestive Tumour Therapy (TTD) Recruiting Madrid, Spain, 28046 Contact: Inmaculada Ruiz de Mena, PhD 0034 91 378 82 75 ttd@ttdgroup.org Collapse << - 参考文献
- [1] Minnaard-Huiban M, Emmen JM, et al. Fadrozole reverses cardiac fibrosis in spontaneously hypertensive heart failure rats: discordant enantioselectivity versus reduction of plasma aldosterone. Endocrinology. 2008 Jan;149(1):28-31.
- [2] Browne LJ, Gude C, Rodriguez H, Steele RE, Bhatnager A. Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease. J Med Chem. 1991;34(2):725-736.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 102676-47-1 | 储存条件 |
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| 分子式 | C14H13N3 | 运输 | 蓝冰 | |||||||
| 分子量 | 223.27 | 别名 | CGS 16949A free base;(Rac)-FAD286;CGS-16949A;法倔唑 | |||||||
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动物实验配方 |
