CAS No.: 1995893-58-7
FEN1-IN-4 Catalog No. CSN20337
Synonyms: FEN1 Inhibitor C2;JUN93587
FEN1 inhibitor C2 is an inhibitor of flap endonuclease 1 (FEN1) which is required for proficient DNA replication and the repair of DNA damage.
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纯度 & 质量文件
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靶点选择性
生物活性
- 描述
- 参考文献
- [1] Ward TA, McHugh PJ, Durant ST. Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes. PLoS One. 2017 Jun 19;12(6):e0179278.
- [2] Exell JC, Thompson MJ, Finger LD, et al. Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site. Nat Chem Biol. 2016;12(10):815-821.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1995893-58-7 | 储存条件 |
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| 分子式 | C12H12N2O3 | 运输 | 蓝冰 | |||
| 分子量 | 232.24 | 别名 | FEN1 Inhibitor C2;JUN93587 | |||
| 溶解度 |
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动物实验配方 |
