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CAS No.: 34597-40-5

Fenoprofen Calcium/非诺洛芬钙 Catalog No. CSN11003

Synonyms: Calcium fenoprofen;Fenoprofen calcium anhydrous;Nalfon

Fenoprofen Calcium is COX-1/2 inhibitor used as an NSAID. It can also inhibit fatty acid oxidation and acts as a peroxisome proliferator.

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描述Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent. Fenoprofen is a nonsteroidal antiinflammatory drug (NSAID) used in the treatment of acute pain and chronic arthritis^[3]. Oral fenoprofen 200 mg is effective at treating moderate to severe acute postoperative pain, based on limited data for at least 50% pain relief over 4 to 6 hours^[4]. A significant increasing relationship exists between efficacy and dose of fenoprofen, suggesting that relatively larger doses of fenoprofen will achieve greater amounts of efficacy^[5]. Mean daily fecal blood loss was significantly lower (P = 0.03) with enteric-coated (mean +/- SD, 1.104 +/- 0.961 ml/day) than with plain fenoprofen calcium (mean +/- SD, 1.686 +/- 0.858 ml/day), suggesting that tolerance of fenoprofen can be improved with administration in an enteric-coated form^[6].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.9135 mL
- 9.5675 mL
- 19.1351 mL
- 5 mM
- 0.3827 mL
- 1.9135 mL
- 3.8270 mL
- 10 mM
- 0.1914 mL
- 0.9568 mL
- 1.9135 mL

技术信息

CAS号

34597-40-5

储存条件

粉末: Inert atmosphere,Store in freezer, under -20°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C30H26CaO6

运输

蓝冰

分子量

522.60

别名

Calcium fenoprofen;Fenoprofen calcium anhydrous;Nalfon;非诺洛芬钙

溶解度

DMSO	104.0 mg/mL (199.0 mM)
Water	Insoluble
Ethanol	10.0 mg/mL (19.1 mM)

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