CAS No.: 1088991-73-4
Filorexant Catalog No. CSN13779
Synonyms: MK-6096
MK-6096 is an orally bioavailable potent and selective reversible antagonist of OX1 and OX2 receptor (< 3 nM in binding).
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01021852 Primary Insomnia Phase 2 Completed - - NCT01554176 Major Depressive Disorder, Rec... more >>urrent Collapse << Phase 2 Terminated(Low Enrollment) - - NCT01554176 - - Terminated(Low Enrollment) - - - 更多
- 参考文献
- [1] Coleman PJ, Schreier JD, et al. Discovery of [(2R,5R)-5-{[(5-fluoropyridin-2-yl)oxy] methyl}-2-methylpiperidin-1-yl] [5-methyl--(pyrimidin-2-yl)phenyl] methanone (MK-6096): a dual orexin receptor antagonist with potent sleep-promoting properties. ChemMedChem. 2012 Mar 5;7(3):415-24, 337.
- [2] Winrow CJ, Gotter AL, et al. Pharmacological characterization of MK-6096 - a dual orexin receptor antagonist for insomnia. Neuropharmacology. 2012 Feb;62(2):978-87.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1088991-73-4 | 储存条件 |
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| 分子式 | C24H25FN4O2 | 运输 | 蓝冰 | |||
| 分子量 | 420.48 | 别名 | MK-6096 | |||
| 溶解度 |
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动物实验配方 |
