CAS No.: 939055-18-2
FIPI Catalog No. CSN16514
Synonyms: 5-Fluoro-2-indolyl deschlorohalopemide
FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM) preventing PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Su W, Yeku O, et al. 5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis. Mol Pharmacol. 2009 Mar;75(3):437-46.
- [2] Monovich L, Mugrage B, et al. Optimization of halopemide for phospholipase D2 inhibition. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2310-1.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 939055-18-2 | 储存条件 |
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| 分子式 | C23H24FN5O2 | 运输 | 蓝冰 | |||||
| 分子量 | 421.47 | 别名 | 5-Fluoro-2-indolyl deschlorohalopemide | |||||
| 溶解度 |
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动物实验配方 |
