|2-(4-(3-(2-(三氟甲基)-10H-吩噻嗪-10-基)丙基)哌嗪-1-基)乙醇盐酸盐|CsnPharm

CAS No.: 146-56-5

Fluphenazine 2HCl/盐酸氟奋乃静 Catalog No. CSN11042

Synonyms: Prolixin;Fluphenazine (hydrochloride);SQ 4,918

Fluphenazine 2HCl is a inhibitor of D1DR and D2DR. It has been used to deliver fluphenazine to biological systems and also used as an antipsychotic.

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Fluphenazine dihydrochloride is a phenothiazine-class D1DR and D2DR inhibitor; used to deliver Fluphenazine to biological systems in studies probing the effects and metabolic fates of this commonly used dopamine antagonist^[3]. Dopamine receptor antagonists, including fluphenazine (0.1-1.0 mg/kg i.p.) prevented apomorphine- and lisuride-induced emesis but were less potent or had inconsistent actions to antagonise cisplatin- or ipecacuanha-induced emesis and failed to inhibit the emesis induced by copper sulphate^[4]. Fluphenazine can be an effective treatment for multiple tics in patients with dose-limiting side effects related to haloperidol^[5]. Fluphenazine treatment produced VCM (Vacuous chewing movements) in 70% of rats and the concomitant treatment with resveratrol decreased the prevalence to 30%, but did not modify the intensity of VCMs. Furthermore, the fluphenazine administration reduced the locomotor and exploratory activity of animals in the open field test. Resveratrol co-treatment was able to protect the reduction of both parameters^[6].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.9591 mL
- 9.7954 mL
- 19.5908 mL
- 5 mM
- 0.3918 mL
- 1.9591 mL
- 3.9182 mL
- 10 mM
- 0.1959 mL
- 0.9795 mL
- 1.9591 mL

技术信息

CAS号

146-56-5

储存条件

粉末: Inert atmosphere,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C22H28Cl2F3N3OS

运输

蓝冰

分子量

510.44

别名

Prolixin;Fluphenazine (hydrochloride);SQ 4,918;Fluphenazine hydrochloride;Anatensol;Lyorodin;Mirenil;盐酸氟奋乃静

溶解度

DMSO	250.0 mg/mL (489.8 mM) warming
Water	80.0 mg/mL (156.7 mM)

动物实验配方

0.5% CMC-Na

30 mg/mL

suspension

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

Fluphenazine 2HCl/盐酸氟奋乃静 Catalog No. CSN11042

靶点选择性

请登录您的专属账户

确认信息