CAS No.: 864863-72-9
FPTQ Catalog No. CSN18973
FPTQ is mGluR1 antagonist with IC50 of 6 nM and 1.4 nM for human and mouse mGluR1 respectively.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Fujinaga M, Yamasaki T, et al. Synthesis and evaluation of 6-[1-(2-[(18)F] fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl] quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain. Bioorg Med Chem. 2011 Jan 1;19(1):102-10.
- [2] Suzuki G, Kawagoe-Takaki H, et al. Correlation of receptor occupancy of metabotropic glutamate receptor subtype 1 (mGluR1) in mouse brain with in vivo activity of allosteric mGluR1 antagonists. J Pharmacol Sci. 2009 Jul;110(3):315-25.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 864863-72-9 | 储存条件 |
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| 分子式 | C17H12FN5 | 运输 | 蓝冰 | |
| 分子量 | 305.31 | 别名 |
