|硫酸庆大霉素|CsnPharm

CAS No.: 1405-41-0

硫酸庆大霉素 Catalog No. CSN11090

Synonyms: 硫酸庆大霉素;庆大霉素硫酸盐

Gentamycin sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.

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描述Gentamicin sulfate, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. It inhibits DNase I with an IC50 of 0.57 mM^[3]. Gentamicin is a more effective in vitro bacterial inhibitor than combined penicillinstreptomycin, is nontoxic to tissue culture monolayers, and does not inhibit virus replication^[4]. Gentamicin sulfate (GS) is used usually as intravenous or intramuscular solution because of its poor oral bioavailability^[5]. Ototoxicity was greater when gentamicin was administered during their diurnal rest than during nocturnal activity. A dosing paradigm may be used to deliver a lower therapeutic antimicrobial concentration during the nighttime rest period when the studied adverse effects are of highest risk^[6].
临床研究

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参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号

1405-41-0

储存条件

粉末: Inert atmosphere,2-8°C

液体: -20°C:3-6 月 -80°C:12月

分子式

H2O4S.xUnspecified

运输

蓝冰

分子量

0.00

别名

硫酸庆大霉素;庆大霉素硫酸盐

溶解度

DMSO	Insoluble
Water	98
Ethanol	Insoluble

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