400-920-2911 sales@csnpharm.cn
您的位置 : 首页 / Membrane Transporter/Ion Channel / Potassium Channel / Gliclazide/格列齐特
CAS No.: 21187-98-4
Synonyms: S1702;SE1702;Diamicron
Gliclazide is a blocker of pancreatic β-cell ATP-sensitive potassium channels with IC50 of 184 nM in murine. It belongs to the sulfonylurea class of insulin secretagoguesIt. Gliclazide is an antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT02476760 | - | - | Completed | - | Canada, Quebec ... more >> Lady Davis Institute for Medical Research, Jewish General Hospital Montreal, Quebec, Canada, H3T1E2 Collapse << |
NCT02456428 | - | - | Completed | - | Canada, Quebec ... more >> Lady Davis Institute for Medical Research, Jewish General Hospital Montreal, Quebec, Canada, H3T1E2 Collapse << |
NCT02475499 | - | - | Completed | - | Canada, Quebec ... more >> Lady Davis Institute for Medical Research, Jewish General Hospital Montreal, Quebec, Canada, H3T1E2 Collapse << |
实验方案
技术信息
CAS号 | 21187-98-4 | 储存条件 |
|
|||||
分子式 | C15H21N3O3S | 运输 | 蓝冰 | |||||
分子量 | 323.41 | 别名 | S1702;SE1702;Diamicron;Glimicron;Nordialex;Diaikron;S-852;格列齐特 | |||||
溶解度 |
|
动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02476760 | - | - | Completed | - | Canada, Quebec ... more >> Lady Davis Institute for Medical Research, Jewish General Hospital Montreal, Quebec, Canada, H3T1E2 Collapse << |
NCT02456428 | - | - | Completed | - | Canada, Quebec ... more >> Lady Davis Institute for Medical Research, Jewish General Hospital Montreal, Quebec, Canada, H3T1E2 Collapse << |
NCT02475499 | - | - | Completed | - | Canada, Quebec ... more >> Lady Davis Institute for Medical Research, Jewish General Hospital Montreal, Quebec, Canada, H3T1E2 Collapse << |
NCT03092076 | Healthy | Phase 1 | Completed | - | - |
NCT01798706 | Type 2 Diabetes | Phase 3 | Completed | - | - |
NCT01798706 | - | - | Completed | - | - |
NCT01340768 | Type 2 Diabetes Mellitus | Phase 3 | Completed | - | - |
NCT01340768 | - | - | Completed | - | - |
NCT01357135 | - | - | Completed | - | - |
NCT01131182 | - | - | Completed | - | - |
NCT00830297 | Hyperglycemia | Phase 2 | Completed | - | Austria ... more >> Medical University of Vienna, Department of Internal Medicine III Vienna, Austria, 1090 Collapse << |
NCT01131182 | Type 2 Diabetes Mellitus (T2DM... more >>) Collapse << | Phase 4 | Completed | - | - |
NCT00978263 | Diabetes | Not Applicable | Completed | - | China, Chongqing ... more >> the First Affiliated Hospital of Chongqing Medical University Chongqing, Chongqing, China, 400016 Collapse << |
NCT01076075 | Type 2 Diabetes Mellitus | Phase 3 | Completed | - | - |
NCT01584232 | Type 2 Diabetes Mellitus | Phase 3 | Completed | - | Japan ... more >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Aichi, Japan, 448-0852 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Chiba, Japan, 286-0048 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Ehime, Japan, 790-0024 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Fukuoka, Japan, 819-0168 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Hokkaido, Japan, 0530018 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Kagoshima, Japan, 8910401 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Kanagawa, Japan, 247-0055 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Kumamoto, Japan, 860-0811 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Kyoto, Japan, 606-8397 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Nagano, Japan, 385-0022 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Nagasaki, Japan, 857-1195 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Ooita, Japan, 8700039 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Osaka, Japan, 598-0048 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Tokyo, Japan, 103-0028 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Yamaguchi, Japan, 754-0002 Collapse << |
NCT01357135 | - | - | Completed | - | - |
NCT01076075 | - | - | Completed | - | - |
NCT01697592 | Type 2 Diabetes Mellitus | Phase 3 | Completed | - | - |
NCT03076112 | Type 2 Diabetes Mellitus | Phase 3 | Recruiting | December 30, 2019 | Korea, Republic of ... more >> Seoul National University Bundang Hospital Recruiting Seongnam, Gyeonggi, Korea, Republic of, 463-707 Contact: Soo Lim, MD, PHD 82-31-787-7035 limsoo@snu.ac.kr Contact: Kyoung Min Kim, MD, PHD 82-31-787-7047 kyoungmin02@gmail.com Principal Investigator: Soo Lim, MD, PHD Collapse << |
NCT01944618 | - | - | Terminated() | - | Australia, Victoria ... more >> Local Institution Clayton, Victoria, Australia, VIC 3168 Collapse << |
NCT03125694 | Uncontrolled Type 2 Diabetes M... more >>ellitus Collapse << | Phase 3 | Completed | - | Iran, Islamic Republic of ... more >> Tehran University of Medical Sciences Tehran, Iran, Islamic Republic of Collapse << |
NCT01697592 | - | - | Completed | - | - |
NCT00147836 | Type 2 Diabetes Mellitus | Not Applicable | Completed | - | China, Guangdong ... more >> the first Affiliated Hospital of Sun Yat-Sen university Guangzhou, Guangdong, China, 510080 Collapse << |
NCT00347100 | Diabetes Mellitus, Type 2 | Phase 4 | Completed | - | China ... more >> Sanofi-Aventis Beijing, China Collapse << |
NCT00367055 | Type 2 Diabetes Mellitus | Phase 4 | Completed | - | - |
NCT00367055 | - | - | Completed | - | - |
NCT00379769 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | - |
NCT01584232 | - | - | Completed | - | - |
NCT02092597 | Type 2 Diabetes Mellitus | Phase 4 | Completed | - | Czechia ... more >> General University Hospital Prague, Czechia, 128 08 Collapse << |
NCT01706211 | Diabetes Mellitus Non Insulin ... more >>Dependent Oral Agent Therapy Collapse << | Phase 3 | Completed | - | Taiwan ... more >> National Taiwan University Hospital Taipei, Taiwan, 10002 Collapse << |
NCT02133118 | - | - | Completed | - | Netherlands ... more >> Isala Zwolle, Overijssel, Netherlands, 8000 AB Collapse << |
NCT00379769 | - | - | Completed | - | - |
NCT02526810 | Diabetes Mellitus, Type 2 | Phase 4 | Unknown | September 2016 | China, Guangdong ... more >> Endocrinology department of the Third Affiliated Hospital of Sun Yet-san University Recruiting Guangzhou City, Guangdong, China, 510630 Contact: Zeng Longyi, Professor 0086-020-85252160 zssynfmk@163.com Contact: Lin Shuo, Doctor 0086-020-85253408 littltpig@yeah.net Principal Investigator: Zeng Longyi, Professor Sub-Investigator: lin Shuo, Doctor Collapse << |
NCT01195259 | - | - | Completed | - | - |
NCT01590771 | Type 2 Diabetes Mellitus | Phase 3 | Completed | - | - |
NCT01590771 | - | - | Completed | - | - |
NCT01426737 | Type 2 Diabetes | Phase 4 | Unknown | January 2013 | Switzerland ... more >> Universitiy Hospital Recruiting Zurich, Switzerland Collapse << |
NCT02694263 | Diabetes Mellitus, Type 2 | Phase 4 | Recruiting | September 2018 | United Kingdom ... more >> University Hospitals of Leicester NHS Trust Recruiting Leicester, Leicestershire, United Kingdom, LE5 4PW Contact: Emer Brady, PhD 0116248 ext 8959 emer.brady@uhl-tr.nhs.uk Contact: Natasha Wileman, MSc 0116258 ext 8929 natasha.wileman@uhl-tr.nhs.uk University Hospitals Birmingham NHS Foundation Trust Recruiting Birmingham, West Midlands, United Kingdom, B15 2TH Contact: Wasim Hanif 0121371 ext 4404 wasim.hanif@uhb.nhs.uk Contact: Deborah Smith 0121371 ext 4707 deborah.smith@uhb.nhs.uk Collapse << |
NCT02879409 | Diabetes Mellitus Type 2 | Not Applicable | Recruiting | August 2019 | Qatar ... more >> Hamad Medical Corporation Recruiting Doha, Qatar, 3050 Contact: Ibrahim Janahi, MD 4439-2434 ext 00974 Imohd@hamad.qa Principal Investigator: Ibrahim Janahi, MD Sub-Investigator: Mashhood Siddique, MD Sub-Investigator: Hamda Ali, MD Collapse << |
NCT01242215 | Type 2 Diabetes Mellitus | Phase 3 | Completed | - | Japan ... more >> Chubu, Japan Chugoku, Japan Hokkaido, Japan Kansai, Japan Kantou, Japan Kyushu, Japan Touhoku, Japan Collapse << |
NCT00700856 | Type 2 Diabetes Mellitus ... more >> Cardiovascular Disease Collapse << | Phase 4 | Unknown | December 2018 | - |
NCT01963130 | - | - | Completed | - | Turkey ... more >> Bezmialem VU Istanbul, Turkey, 34093 Collapse << |
NCT02587741 | Diabetic Retinopathy | Early Phase 1 | Recruiting | July 2025 | China, Guangdong ... more >> the third affiliated hospital of Sun yet-san university Recruiting Guangzhou, Guangdong, China, 510000 Contact: Zhu Bilian, master +8613580364394 bilianzhu@qq.com Contact: Tang Xixiang, master +8613570434387 txx_8711@126.com Collapse << |
NCT00464594 | Diabetes Mellitus | Not Applicable | Unknown | - | Japan ... more >> Tokyo Medical and Dental University Recruiting Tokyo, Japan, 113-8519 Contact 03-3813-6111 Collapse << |
NCT00506194 | Type 2 Diabetes | Not Applicable | Completed | - | Taiwan ... more >> Division of Endocrinology and Metabolism, Department of Medicine Taipei, Taiwan, 112 Collapse << |
NCT03499808 | Amorphous, Eosinophilic, and A... more >>cellular Deposit Constipation Diarrhea Early Satiety Gastrointestinal Hemorrhage Hepatomegaly Lymphadenopathy Macroglossia Nausea Primary Systemic Amyloidosis Purpura Recurrent Primary Amyloidosis Refractory Primary Amyloidosis Collapse << | Phase 2 | Recruiting | July 31, 2025 | - |
NCT03196154 | - | - | Completed | - | Malaysia ... more >> Clinical Research Centre, Sarawak General Hospital Kuching, Sarawak, Malaysia, 93586 Collapse << |
NCT01269996 | Type 2 Diabetes Mellitus | Phase 4 | Completed | - | Hong Kong ... more >> Department of Medicine & Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong Hong Kong, Hong Kong Collapse << |
NCT01771185 | Type 2 Diabetes | Not Applicable | Unknown | December 2013 | - |
NCT00169624 | Coronary and Peripheral Endoth... more >>elial Dysfunction Collapse << | Phase 3 | Terminated | - | France ... more >> Laurent SEBBAG Lyon, France, 69677 Collapse << |
NCT00145925 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | Australia, Victoria ... more >> The University of Melbourne Melbourne, Victoria, Australia, 3010 Canada, Quebec University of Montreal Montreal, Quebec, Canada, H26 1X2 China, Beijing Cardiovascular Institute & Fu Wai Hospital Xicheng District, Beijing, China, 100037 Netherlands The Julius Center for Health Sciences and Primary Care Utrecht, Netherlands, 3508 BA United Kingdom Imperial College School of Medicine London, United Kingdom, W2 1PG Collapse << |
NCT00780715 | Diabetes Mellitus, Type 2 | Phase 4 | Completed | - | United Kingdom ... more >> Ninewells Hospital & Medical School Dundee, United Kingdom, DD1 9SY Collapse << |
NCT00780715 | - | - | Completed | - | - |
NCT00808860 | Type 2 Diabetes | Phase 1 Phase 2 | Completed | - | Vietnam ... more >> National Institute of Gerontology, HMU Hanoi, Vietnam Collapse << |
NCT00949286 | - | - | Completed | - | - |
NCT01847144 | Type 2 Diabetes | Phase 4 | Completed | - | United Kingdom ... more >> NIHR Exeter Clinical Research Facility, Royal Devon & Exeter NHS Foundation Trust Exeter, Devon, United Kingdom, EX2 5DW Collapse << |
NCT03433248 | Type2 Diabetes | Phase 4 | Recruiting | December 1, 2020 | Netherlands ... more >> VU University Medical Center Recruiting Amsterdam, Noord-Holland, Netherlands, 1081HV Contact: Michaël JB van Baar, MD +31 20 444 4709 m.vanbaar@vumc.nl Contact: Daniël H van Raalte, MD PhD +31 20 444 0534 d.vanraalte@vumc.nl Principal Investigator: Mark HH Kramer, MD PhD Principal Investigator: Daniël H van Raalte, MD PhD Collapse << |
NCT01709305 | Type 2 Diabetes Mellitus | Phase 4 | Completed | - | - |
NCT00225342 | Angina Pectoris ... more >> Diabetes Mellitus, Type 2 Collapse << | Phase 4 | Withdrawn | - | United Kingdom ... more >> Cardiology Department, Glasgow Royal Infirmary Glasgow, United Kingdom, G4 0SF Collapse << |
NCT01709305 | - | - | Completed | - | - |
NCT01022762 | Diabetes Diab... more >>etes Mellitus, Type 2 Collapse << | Phase 4 | Completed | - | China, Shanghai ... more >> Shanghai, Shanghai, China, 200025 Collapse << |
NCT00102388 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | Germany ... more >> Novartis Investigative Site Investigative Centers, Germany Switzerland Novartis Pharmaceuticals Basel, Switzerland Collapse << |
NCT01195532 | - | - | Unknown | January 2011 | Taiwan ... more >> Taipei Medical University - Municipal Wan Fang Hospital Recruiting Taipei, Taiwan, Taiwan Contact: Hsingjin E Liu, MD, PhD E Liu, MD, PhD 8862-29307930 ext 2548 liuxx086@yahoo.com.tw Principal Investigator: Hsingjin E Liu, MD, PhD E Liu, MD, PhD Collapse << |
NCT00102466 | Diabetes Mellitus, Type 2 | Phase 3 | Completed | - | Germany ... more >> Investigative Centers Nurnberg, Germany Switzerland Novartis Pharmaceuticals Basel, Switzerland Collapse << |
NCT00738088 | Diabetes Mellitus, Type 2 | Phase 4 | Terminated(Following Regulator... more >> inspection in 2009, study terminated as inadequate approvals were in place) Collapse << | - | United Kingdom ... more >> NHS Tayside Dundee, United Kingdom, DD1 9SY Collapse << |
NCT03246828 | MODY1 MODY3 | Not Applicable | Recruiting | August 2018 | United Kingdom ... more >> Clinical Research Unit, OCDEM, Churchill Hospital Recruiting Oxford, Oxfordshire, United Kingdom, OX3 7LE Contact: Ioannis Spiliotis, MD +44-1865857255 ioannis.spiliotis@ocdem.ox.ac.uk Principal Investigator: Ioannis Spiliotis, MD Collapse << |
NCT01022762 | - | - | Completed | - | - |
NCT01758380 | Type 2 Diabetes Mellitus | Phase 4 | Completed | - | - |
NCT03068065 | Non-Alcoholic Fatty Liver Dise... more >>ase Type2 Diabetes Collapse << | Phase 4 | Completed | - | China, Jiangsu ... more >> at Division of Endocrinology, the Affiliated Drum Tower Hospital of Nanjing University Nanjing, Jiangsu, China, 210008 Collapse << |
NCT01991197 | Psoriasis Typ... more >>e 2 Diabetes Mellitus Collapse << | Phase 2 | Completed | - | Ireland ... more >> The Adelaide and Meath Hospital Dublin 24, Ireland UCD Clinical Research Centre, St Vincent's University Hospital, Dublin 4, Ireland Collapse << |
NCT02925559 | Diabetes Mellitus, Type 2 | Phase 4 | Unknown | December 2017 | Brazil ... more >> Centro de Diabetes Curitiba Curitiba, Parana, Brazil, 80810040 Collapse << |
NCT00736515 | Type 2 Diabetes | Phase 4 | Completed | - | China, Beijing ... more >> Peking University First Hospital Beijing, Beijing, China, 100034 Beijing Hospital Beijing, Beijing, China, 100730 China, Guangdong Guangdong General Hospital Guangzhou, Guangdong, China, 510080 China, Heilongjiang The 2nd Affiliated Hospital of Harbin Medical University Harbin, Heilongjiang, China, 150086 China, Hubei Tongji Hospital of Tongji Medical College of Huazhong University of Science & Technology Wuhan, Hubei, China, 430030 China, Shanghai Shanghai Sixth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine Shanghai, Shanghai, China, 200233 China, Sichuan West China Hospital of Sichuan University Chengdu, Sichuan, China, 610041 China, Zhejiang SIR RUN RUN SHAW Hospital Affiliated to Zhejiang University School of Medicine Hangzhou, Zhejiang, China, 310016 Collapse << |
NCT02682563 | Diabetes Mellitus, Type 2 ... more >> Diabetic Nephropathies Collapse << | Phase 4 | Completed | - | Netherlands ... more >> VU University Medical Center Amsterdam, Noord-Holland, Netherlands, 1081 HV Collapse << |
NCT03313661 | Diabetes | Phase 3 | Recruiting | December 2020 | Egypt ... more >> Sherief Abd-Elsalam Recruiting Cairo, Egypt Contact: Sherief Abd-elsalam, lecturer 00201000040794 Sherif_tropical@yahoo.com Collapse << |
NCT01679899 | Type 2 Diabetes Mellitus ... more >> Menopause Osteoporosis Osteopenia Collapse << | Phase 4 | Completed | - | Brazil ... more >> Centro de Diabetes Curitiba Curitiba, Parana, Brazil, 80810040 Collapse << |
NCT02777671 | Epilepsy | Phase 1 | Completed | - | Portugal ... more >> Human Pharmacology Unit S. Mamede do Coronado, Portugal, 4745-457 Collapse << |
NCT03467945 | Healthy | Phase 1 | Completed | - | Germany ... more >> Please Contact the Merck KGaA Communication Center Darmstadt, Germany, 64293 Collapse << |
NCT02980757 | Comparative Bioavailability | Phase 1 | Withdrawn | - | Jordan ... more >> International Pharmaceutical Research Center Amman, Jordan Collapse << |
NCT03705195 | Type 2 Diabetes Mellitus | Not Applicable | Recruiting | June 20, 2019 | United Kingdom ... more >> Ninewells Hospital and Medical School Recruiting Dundee, United Kingdom, DD1 9SY Contact: Ruth LM Cordiner, MBChB, MRCP 0044 1382 386 715 ext 00441382386715 r.cordiner@dundee.ac.uk Principal Investigator: Ruth LM Cordiner Collapse << |
NCT03467971 | Healthy | Phase 1 | Completed | - | Mexico ... more >> CECYPE Mexico City, Mexico Collapse << |
NCT02643329 | Healthy | Phase 1 | Completed | - | Hong Kong ... more >> Phase 1 Clinical Trial Centre, The Chinese University of Hong Kong New Territories, Hong Kong Collapse << |
NCT02610088 | Diabetes | Phase 4 | Completed | - | Korea, Republic of ... more >> Seoul National University Bundang Hospital Seongnam, Gyeonggi, Korea, Republic of, 463-707 Collapse << |
NCT01420692 | Type 2 Diabetes Mellitus | Not Applicable | Completed | - | Turkey ... more >> Ankara University Medical Faculty Dept. of Endocrinology and Metabolism Ankara, Turkey, 06100 Collapse << |
NCT02201602 | Diabetes | Phase 4 | Completed | - | Singapore ... more >> Khoo Teck Puat Hospital Singapore, Singapore, 768828 Collapse << |
联系我们
官方电话:400-920-2911
二维码
微信公众号 CSN官网