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CAS No.: 1196546-33-4
GNE-8525 is a potent and selective pan-TRK inhibitor, demonstrated potent antiproliferation activity with IC50 = 0.003 μM. In a tumor xenograft model derived from the KM12 cell line, GNE-8525 demonstrated in vivo antitumor efficacy when administered at ascending doses twice daily (bid) for 14 days in rats.
生物活性
实验方案
技术信息
CAS号 | 1196546-33-4 | 储存条件 |
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分子式 | C31H30FN7O | 运输 | 蓝冰 | |
分子量 | 535.61 | 别名 |
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