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CAS No.: 26833-87-4
Synonyms: Omacetaxine mepesuccinate;HHT;Omacetaxine
Homoharringtonine is a cytotoxic alkaloid from the evergreen tree.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT03165851 | - | - | Completed | - | China, Tianjin ... more >> InstituteHBDH Tianjin, Tianjin, China, 300020 Collapse << |
NCT02835794 | Myelodysplastic Syndromes | Phase 1 Phase 2 | Withdrawn(Lack of funding to s... more >>upport clinical trial) Collapse << | December 2018 | United States, Florida ... more >> University of Florida Health Shands Cancer Hospital Gainesville, Florida, United States, 32608 Collapse << |
NCT02440568 | Acute Myeloid Leukemia | Phase 1 Phase 2 | Recruiting | May 5, 2019 | United States, Illinois ... more >> University of Illinois at Chicago Recruiting Chicago, Illinois, United States, 60612 Contact: John G Quigley, MD 312-413-1300 seanq@uic.edu Contact: Stephanie Barath, BS (312) 355-5767 sbarat2@uic.edu Collapse << |
实验方案
技术信息
CAS号 | 26833-87-4 | 储存条件 |
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分子式 | C29H39NO9 | 运输 | 蓝冰 | |||
分子量 | 545.62 | 别名 | Omacetaxine mepesuccinate;HHT;Omacetaxine;NSC 141633;CGX-635;高三尖杉酯碱 | |||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT03165851 | - | - | Completed | - | China, Tianjin ... more >> InstituteHBDH Tianjin, Tianjin, China, 300020 Collapse << |
NCT02835794 | Myelodysplastic Syndromes | Phase 1 Phase 2 | Withdrawn(Lack of funding to s... more >>upport clinical trial) Collapse << | December 2018 | United States, Florida ... more >> University of Florida Health Shands Cancer Hospital Gainesville, Florida, United States, 32608 Collapse << |
NCT02440568 | Acute Myeloid Leukemia | Phase 1 Phase 2 | Recruiting | May 5, 2019 | United States, Illinois ... more >> University of Illinois at Chicago Recruiting Chicago, Illinois, United States, 60612 Contact: John G Quigley, MD 312-413-1300 seanq@uic.edu Contact: Stephanie Barath, BS (312) 355-5767 sbarat2@uic.edu Collapse << |
NCT02141477 | Leukemia | Phase 1 | Terminated(Slow Accrual-2 pati... more >>ents were registered Phase I and none in Phase II) Collapse << | - | United States, Texas ... more >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
NCT03564873 | High Grade Myelodysplastic Syn... more >>dromes Collapse << | Phase 1 Phase 2 | Recruiting | June 2026 | United States, Colorado ... more >> Universtiy of Colorado Denver Recruiting Aurora, Colorado, United States, 80045 Contact: Lauren Dabdoub 720-848-1156 lauren.dabdoub@ucdenver.edu Principal Investigator: Daniel Pollyea, MD Collapse << |
NCT02159872 | Leukemia | Phase 2 | Active, not recruiting | May 2019 | United States, Texas ... more >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
NCT01417767 | Myelodysplastic Syndromes | Phase 2 Phase 3 | Unknown | September 2013 | China, Shanghai ... more >> Shanghai 6th People's Hospital Not yet recruiting Shanghai, Shanghai, China, 200233 Contact: Xiao Li lixiao3326@yahoo.com.cn Principal Investigator: Xiao Li Collapse << |
NCT02029417 | Acute Myeloid Leukemia With Mu... more >>ltilineage Dysplasia Following Myelodysplastic Syndrome Adult Acute Megakaryoblastic Leukemia (M7) Adult Acute Minimally Differentiated Myeloid Leukemia (M0) Adult Acute Monoblastic Leukemia (M5a) Adult Acute Monocytic Leukemia (M5b) Adult Acute Myeloblastic Leukemia With Maturation (M2) Adult Acute Myeloblastic Leukemia Without Maturation (M1) Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities Adult Acute Myeloid Leukemia With Del(5q) Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) Adult Acute Myelomonocytic Leukemia (M4) Adult Erythroleukemia (M6a) Adult Pure Erythroid Leukemia (M6b) Secondary Acute Myeloid Leukemia Untreated Adult Acute Myeloid Leukemia Collapse << | Phase 2 | Terminated(Major revisions nee... more >>ded in study) Collapse << | - | United States, New York ... more >> Roswell Park Cancer Institute Buffalo, New York, United States, 14263 Collapse << |
NCT02029417 | - | - | Terminated(Major revisions nee... more >>ded in study) Collapse << | - | - |
NCT01844869 | Hematologic Malignancies ... more >> Solid Tumors Collapse << | Phase 1 | Completed | - | Netherlands ... more >> Teva Investigational Site 38045 Amsterdam, Netherlands Collapse << |
NCT01873495 | Acute Myelogenous Leukemia (AM... more >>L) Collapse << | Phase 2 | Completed | - | United States, Georgia ... more >> Emory University Winship Cancer Institute Atlanta, Georgia, United States, 30322 Collapse << |
NCT00003239 | Leukemia | Phase 2 | Completed | - | United States, Texas ... more >> University of Texas - MD Anderson Cancer Center Houston, Texas, United States, 77030-4009 Collapse << |
NCT03453255 | Chemotherapy | Phase 1 Phase 2 | Recruiting | December 31, 2020 | China ... more >> Chinese PLA General Hospital Recruiting Beijing, China, 100853 Contact: Li Yu, M.D. Ph.D. 86-010-55499003 chunhuiliyu@yahoo.com Principal Investigator: Li Yu, M.D. Ph.D. Collapse << |
NCT00030355 | Leukemia | Phase 1 Phase 2 | Withdrawn | - | United States, Texas ... more >> M. D. Anderson Cancer Center at University of Texas Houston, Texas, United States, 77030-4009 Collapse << |
NCT00002574 | Leukemia | Phase 2 | Completed | - | United States, Massachusetts ... more >> Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, Texas University of Texas - MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
NCT02078960 | Chronic Myeloid Leukemia | Phase 1 Phase 2 | Terminated(Inability to accrue... more >> additional sites and enroll an adequate number of subjects.) Collapse << | - | United States, Georgia ... more >> Teva Investigational Site 12550 Atlanta, Georgia, United States, 30322 United States, Indiana Teva Investigational Site 12543 Indianapolis, Indiana, United States, 46237 United States, New York Teva Investigational Site 12547 Buffalo, New York, United States, 14263 United States, Ohio Teva Investigational Site 12546 Cincinnati, Ohio, United States, 45219 United States, Texas Teva Investigational Site 12544 Houston, Texas, United States, 77030 Belgium Teva Investigational Site 37048 Gent, Belgium, 9000 Teva Investigational Site 37047 Leuven, Belgium, 3000 France Teva Investigational Site 35157 Pierre Benite Cedex, France, 69 495 Korea, Republic of Teva Investigational Site 87026 Seoul, Korea, Republic of, 137-701 Collapse << |
NCT00004933 | Leukemia | Phase 3 | Terminated(Poor accrual) | - | - |
NCT00375219 | Chronic Myeloid Leukemia | Phase 2 | Completed | - | - |
NCT00375219 | - | - | Completed | - | - |
NCT00003694 | Chronic Myelogenous Leukemia, ... more >>BCR-ABL1 Positive Chronic Phase Chronic Myelogenous Leukemia Collapse << | Phase 2 | Completed | - | United States, Massachusetts ... more >> Dana-Farber Harvard Cancer Center Boston, Massachusetts, United States, 02115 Collapse << |
NCT00675350 | Hematologic Tumors | Phase 1 | Completed | - | United States, Texas ... more >> Mary Crowley Cancer Research Center Dallas, Texas, United States, 75201 Collapse << |
NCT00006364 | Childhood Chronic Myelogenous ... more >>Leukemia Chronic Myelogenous Leukemia, BCR-ABL1 Positive Chronic Phase Chronic Myelogenous Leukemia Relapsing Chronic Myelogenous Leukemia Collapse << | Phase 2 | Completed | - | United States, Texas ... more >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
NCT00462943 | - | - | Completed | - | - |
NCT00114959 | Myeloid Leukemia, Chronic ... more >> Myeloid Leukemia, Chronic, Accelerated-Phase Blast Phase Myeloid Leukemia, Chronic, Chronic-Phase Collapse << | Phase 2 | Terminated(Poor enrollment) | - | United States, Texas ... more >> Univ. of Texas M.D. Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
NCT00114959 | - | - | Terminated(Poor enrollment) | - | - |
NCT03170895 | AML FLT3-ITD ... more >>Mutation Collapse << | Phase 2 | Recruiting | October 1, 2021 | Hong Kong ... more >> The University of Hong Kong Recruiting Hong Kong, Hong Kong Contact: Chunxiao Zhang, SC 852-22554361 chunxiao@hku.hk Collapse << |
NCT00462943 | Chronic Myeloid Leukemia | Phase 2 | Completed | - | - |
NCT03135054 | AML FLT3-ITD ... more >>Mutation Collapse << | Phase 2 | Recruiting | October 1, 2021 | Hong Kong ... more >> The University of Hong Kong Recruiting Hong Kong, Hong Kong Contact: Chunxiao Zhang, SC 852-22554361 chunxiao@hku.hk Collapse << |
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