CAS No.: 304-20-1
Hydralazine HCl/盐酸肼屈嗪 Catalog No. CSN11163
Synonyms: Hydralazine (hydrochloride);1-Hydrazinophthalazine;Apresoline
Hydralazine HCl is a direct-acting vasodilator that is used as an antihypertensive agent.
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靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02884011 - - Completed - United States, Illinois ... more >> Rush Univeristy Medical Center Chicago, Illinois, United States, 60612 Collapse << NCT03608085 Heart Failure Not Applicable Recruiting May 31, 2019 United States, Rhode Island ... more >> Ocean State Research Institute Recruiting Providence, Rhode Island, United States, 02908 Contact: Mary Ford 401-273-7100 ext 3674 Mary.Ford@va.gov Principal Investigator: Tracey H Taveira, Pharm.D. Sub-Investigator: Philip Haines, MD Sub-Investigator: Wen-Chih Wu, MD Providence VAMC Recruiting Providence, Rhode Island, United States, 02908 Contact: Melanie R Parent, Ba 401-273-7100 ext 6293 Melanie.Parent@va.gov Principal Investigator: Tracey H Taveira, Pharm.D. Collapse << NCT03619317 - - Recruiting August 2020 Denmark ... more >> University Hospital of Aarhus, Department of Cardiology Recruiting Aarhus N, Denmark, 8200 Contact: Mette Søndergaard 30130565 metast@rm.dk Contact: Steen Poulsen steen.hvitfeldt@rm.dk Collapse << - 更多
- 参考文献
- [1] Mazari L, Ouarzane M, et al. Subversion of B lymphocyte tolerance by hydralazine, a potential mechanism for drug-induced lupus. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6317-22. Epub 2007 Apr 2.
- [2] Burcham PC, Pyke SM. Hydralazine inhibits rapid acrolein-induced protein oligomerization: role of aldehyde scavenging and adduct trapping in cross-link blocking and cytoprotection. Mol Pharmacol. 2006 Mar;69(3):1056-65.
- [3] Bourreli B, Pinaud M, Passuti N, Gunst JP, Drouet JC, Remi JP. Additive effects of dihydralazine during enflurane or isoflurane hypotensive anaesthesia for spinal fusion. Can J Anaesth. 1988;35(3 ( Pt 1)):242-248
- [4] Kandler MR, Mah GT, Tejani AM, Stabler SN. Hydralazine for essential hypertension. Cochrane Database Syst Rev. 2010;(8):CD004934. Published 2010 Aug 4
- [5] Genedy S, Khames A, Hussein A, Sarhan H. Hydralazine HCl rapidly disintegrating sublingual tablets: simple dosage form of higher bioavailability and enhanced clinical efficacy for potential rapid control on hypertensive preeclampsia. Drug Des Devel Ther. 2018;12:3753-3766. Published 2018 Nov 5
- [6] Ferdinand KC. Isosorbide dinitrate and hydralazine hydrochloride: a review of efficacy and safety. Expert Rev Cardiovasc Ther. 2005;3(6):993-1001
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 304-20-1 | 储存条件 |
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| 分子式 | C8H9ClN4 | 运输 | 蓝冰 | |||||||||
| 分子量 | 196.64 | 别名 | Hydralazine (hydrochloride);1-Hydrazinophthalazine;Apresoline;Hydralazine Hydrochloride;1-Hydrazinophthalazine hydrochloride;Aiselazine;Hydralazine chloride;mono-Hydrochloride;Hydralazine;Nepresol;盐酸肼屈嗪 | |||||||||
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动物实验配方 |
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| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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| NCT02884011 | - | - | Completed | - | United States, Illinois ... more >> Rush Univeristy Medical Center Chicago, Illinois, United States, 60612 Collapse << |
| NCT03608085 | Heart Failure | Not Applicable | Recruiting | May 31, 2019 | United States, Rhode Island ... more >> Ocean State Research Institute Recruiting Providence, Rhode Island, United States, 02908 Contact: Mary Ford 401-273-7100 ext 3674 Mary.Ford@va.gov Principal Investigator: Tracey H Taveira, Pharm.D. Sub-Investigator: Philip Haines, MD Sub-Investigator: Wen-Chih Wu, MD Providence VAMC Recruiting Providence, Rhode Island, United States, 02908 Contact: Melanie R Parent, Ba 401-273-7100 ext 6293 Melanie.Parent@va.gov Principal Investigator: Tracey H Taveira, Pharm.D. Collapse << |
| NCT03619317 | - | - | Recruiting | August 2020 | Denmark ... more >> University Hospital of Aarhus, Department of Cardiology Recruiting Aarhus N, Denmark, 8200 Contact: Mette Søndergaard 30130565 metast@rm.dk Contact: Steen Poulsen steen.hvitfeldt@rm.dk Collapse << |
| NCT00683696 | - | - | Terminated | - | - |
| NCT00683696 | Heart Failure ... more >> Ventricular Dyssynchrony Collapse << | Phase 2 Phase 3 | Terminated | - | - |
| NCT00283686 | Kidney, Polycystic | Phase 3 | Completed | - | United States, Colorado ... more >> University of Colorado Health Sciences Center Denver (Aurora), Colorado, United States, 800045 United States, Georgia Emory University School of Medicine Atlanta, Georgia, United States, 30322 United States, Kansas University of Kansas Medical Center Kansas City, Kansas, United States, 66160 United States, Massachusetts Tufts University-New England Medical Center Boston, Massachusetts, United States, 02111 Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02215 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 United States, Ohio Cleveland Clinic Foundation Cleveland, Ohio, United States, 44195 Collapse << |
| NCT00000620 | - | - | Completed | - | - |
| NCT00000620 | Atherosclerosis ... more >> Cardiovascular Diseases Hypercholesterolemia Hypertension Diabetes Mellitus, Type 2 Diabetes Mellitus Coronary Disease Collapse << | Phase 3 | Completed | - | United States, Minnesota ... more >> Minneapolis Medical Research Foundation Minneapolis, Minnesota, United States, 55404 United States, New York Columbia University New York, New York, United States, 10027 United States, North Carolina Wake Forest University Winston-Salem, North Carolina, United States, 27106 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Tennessee Veterans Affairs Memphis, Tennessee, United States, 38104 United States, Washington University of Washington Seattle, Washington, United States, 98195 Canada, Ontario McMaster University Hamilton, Ontario, Canada Collapse << |
| NCT01958801 | Horner's Syndrome | Not Applicable | Completed | - | Korea, Republic of ... more >> Daegu Catholic University Medical Center Daegu, Korea, Republic of, 705-718 Collapse << |
| NCT00582777 | Hypertensive Renal Disease | Phase 2 Phase 3 | Completed | - | United States, Alabama ... more >> University of Alabama Birmingham, Alabama, United States, 35233 United States, California University of Southern California Los Angeles, California, United States, 90033 Charles Drew Medical College Los Angeles, California, United States, 90059 University of California at San Diego San Diego, California, United States, 92161 United States, Florida University of Florida Gainesville, Florida, United States, 32611 University of Miami Miami, Florida, United States, 33101 United States, Georgia Emory University Atlanta, Georgia, United States, 30308 United States, Illinois University of Chicago Chicago, Illinois, United States, 60637 United States, Maryland Johns Hopkins University Baltimore, Maryland, United States, 21205 United States, Michigan University of Michigan Ann Arbor, Michigan, United States, 48106 United States, New York Lenox Hill Hospital New York, New York, United States, 10021 United States, Ohio University Hospitals of Cleveland Cleveland, Ohio, United States, 44106 Ohio State University Columbus, Ohio, United States, 43210 United States, South Carolina Medical University of South Carolina Charleston, South Carolina, United States, 29425 United States, Tennessee Vanderbilt University Nashville, Tennessee, United States, 37232 United States, Texas Univesity of Texas Southwestern Medical Center at Dallas Dallas, Texas, United States, 75390 Collapse << |
| NCT00661895 | - | - | Completed | - | - |
| NCT00226096 | CVA (Cerebrovascular Accident)... more >> Cerebral Hemorrhage Intracranial Hemorrhages Collapse << | Not Applicable | Completed | - | Australia, New South Wales ... more >> Concord Hospital Concord, New South Wales, Australia, 2138 Gosford Hospital Gosford, New South Wales, Australia, 2250 St George Hospital Kogarah, New South Wales, Australia, 2217 John Hunter Hospital Newcastle, New South Wales, Australia, 2310 St Vincent's Hospital Sydney, New South Wales, Australia, 2010 Royal Prince Alfred Hospital Sydney, New South Wales, Australia, 2050 Westmead Hospital Westmead, New South Wales, Australia, 2145 Australia, South Australia Royal Adelaide Hospital Adelaide, South Australia, Australia, 5000 Australia, Victoria Royal Melbourne Hospital Melbourne, Victoria, Australia, 3050 St Vincent's Hospital Melbourne, Victoria, Australia, 3065 Box Hill Hospital Melbourne, Victoria, Australia, 3128 Alfred Hospital Melbourne, Victoria, Australia, 3181 Austin Health Melbourne, Victoria, Australia Monash Medical Centre Melbourne, Victoria, Australia Australia, Western Australia Sir Charles Gairdner Hospital Perth, Western Australia, Australia, 6009 China Regional Coordinating Centre: Peking University First Hospital Beijing, China, 100034 Hospitals in China, c/o The George Institute China Beijing, China Regional Coordinating Centre: Centre for Epidemiological Studies and Clinical Trials, Ruijin Hospital, Shanghai Institute of Hypertension, Shanghai Second Medical University Shanghai, China, 200025 New Zealand North Shore Hospital Auckland, New Zealand Christchurch Hospital Christchurch, New Zealand Collapse << |
| NCT00661895 | Hypertension | Phase 4 | Completed | - | United States, Nebraska ... more >> Creighton Community Health Center Omaha, Nebraska, United States, 68104 Collapse << |
| NCT00283686 | - | - | Completed | - | - |
| NCT00512759 | Acute Heart Failure | Phase 4 | Active, not recruiting | December 2019 | Brazil ... more >> Hospital Sao Paolo São Paulo, Brazil, 04024-002 Bulgaria 5-th Multifunctional Hospital for Active Treatment Sofia, Bulgaria National Transport Hospital "Tsar Boris III" Sofia, Bulgaria University Hospital "Tsaritsa Joanna-ISUL" Sofia, Bulgaria Germany University Hospital Mainz Mainz, Germany, 55131 Nuremberg Hospital Nuremberg, Germany, 90419 Spain Hospital Universitari Germans Trias i Pujol Badalona, Spain, 08916 Hospital de la Santa Creu i Sant Pau Barcelona, Spain, 08041 Switzerland University Hospital Basel Basel, BS, Switzerland, 4031 Kantonsspital Aarau Aarau, Switzerland, 5001 Kantonsspital Luzern Luzern, Switzerland, 6000 Kantonsspital St. Gallen St. Gallen, Switzerland, 9007 Collapse << |
| NCT02592499 | End-stage Heart Failure | Not Applicable | Recruiting | December 2022 | Sweden ... more >> Sahlgrenska Univesitetssjukhustet, Transplantationscentrum Recruiting Gothenburg, Sweden, 41234 Contact: Göran Dellgren +46 31-342 88 63 goran.dellgren@vgregion.se Linköping Univ Hospital Recruiting Linköping, Sweden Contact: Peter Wodlin, MD Skåne University Hospital Recruiting Lund, Sweden Contact: Oscar Braun, MD Karolinska Univ Hospital Recruiting Stockholm, Sweden Contact: Lars Lund, MD Univ Hospital of Umeå Recruiting Umeå, Sweden Contact: Krister Lindmark, MD Uppsala Univ Hospital Recruiting Uppsala, Sweden Contact: Ola Vedin, MD Örebro Univ Hospital Recruiting Örebro, Sweden Contact: Barna Szado, MD Collapse << |
| NCT03616730 | - | - | Not yet recruiting | December 30, 2020 | - |
| NCT03147092 | Hypertension ... more >>Blood Pressure Collapse << | Early Phase 1 | Not yet recruiting | June 30, 2021 | - |
| NCT00716079 | Intracerebral Hemorrhage ... more >> Stroke Hypertension Collapse << | Not Applicable | Completed | - | - |
| NCT00716079 | - | - | Completed | - | - |
| NCT00952081 | Hypertension ... more >>Brain Tumor Epilepsy Collapse << | Phase 4 | Completed | - | United States, New York ... more >> NYU Langone Medical Center, Department of Anesthesiology New York, New York, United States, 10016 Collapse << |
| NCT00952081 | - | - | Completed | - | - |
| NCT00684489 | Hypertension | Not Applicable | Completed | - | - |
| NCT01422616 | Ischemic Stroke ... more >> High Blood Pressure Collapse << | Phase 3 | Recruiting | February 2019 | Australia, New South Wales ... more >> Royal Prince Alfred Hospital Recruiting Sydney, New South Wales, Australia, 2050 Contact: Craig S Anderson, MD +61 2 933 4500 canderson@georgeinstitute.org.au Collapse << |
| NCT02620384 | Acute Decompensated Heart Fail... more >>ure Collapse << | Phase 3 | Completed | - | United States, Ohio ... more >> Aultman Health Foundation Canton, Ohio, United States, 44710 Collapse << |
| NCT00000499 | Cardiovascular Diseases ... more >> Heart Diseases Hypertension Vascular Diseases Collapse << | Phase 2 | Completed | - | - |
| NCT02305095 | - | - | Recruiting | June 2019 | - |
| NCT03168529 | Heart Failure | Phase 4 | Recruiting | June 30, 2020 | United States, Michigan ... more >> Wayne State University Recruiting Detroit, Michigan, United States, 48201 Contact: Phillip D Levy, MD, MPH 313-577-1214 plevy@med.wayne.edu Contact: Patrick Medado 3137454621 pbmedado@med.wayne.edu Henry Ford Hospital Not yet recruiting Detroit, Michigan, United States, 48202 Contact: David E Lanfear, MD, MS 313-916-5620 DLANFEA1@hfhs.org Contact: Karen Leszczynski, RN 3139163502 Kleszcz2@hfhs.org Collapse << |
| NCT00223717 | Hypertension | Phase 1 | Completed | - | United States, Tennessee ... more >> Vanderbilt University Nashville, Tennessee, United States, 37232 Collapse << |
| NCT00599235 | Hypertension | Not Applicable | Completed | - | United Kingdom ... more >> University of Edinburgh - Western General Hospital Edinburgh, United Kingdom, EH4 2XU Collapse << |
| NCT01041963 | Continuous Ambulatory Peritone... more >>al Dialysis Collapse << | Phase 4 | Unknown | September 2010 | Thailand ... more >> Chulalongkorn university Recruiting Bangkok, Thailand, 10330 Contact: Talerngsak Kanjanabuch, Assist. Prf. 662-256-4321 ext 211 golfnephro@yahoo.com Principal Investigator: Talerngsak Kanjanabuch, Assist. Prf. Sub-Investigator: Wassawon Wontanatawatot, MD Collapse << |
| NCT01255475 | Heart Failure ... more >> Cardiac Failure Congestive Heart Failure Collapse << | Phase 2 Phase 3 | Completed | - | Brazil ... more >> Heart Institute (InCor) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo São Paulo, SP, Brazil, 05403000 Collapse << |
| NCT00772499 | Hypertension | Phase 4 | Completed | - | United States, North Carolina ... more >> Wake Forest University Baptist Medical Center Winston-Salem, North Carolina, United States, 27157 Collapse << |
| NCT02446652 | Cervical Cancer | Phase 3 | Unknown | August 2018 | Mexico ... more >> National Institute of Cancerology Not yet recruiting Mexico City, DF, Mexico, 14080 Contact: Lucely Cetina, MD, MSc +52 555 628 0400 ext 56101 micuentalucely@yahoo.com Collapse << |
| NCT02522208 | Heart Failure | Phase 1 | Completed | - | United States, Alabama ... more >> Pinnacle Research Group, LLC Anniston, Alabama, United States, 36207 United States, Florida Linfritz Research Institue Inc Coral Gables, Florida, United States, 33134 Jacksonville Center for Clinical Research Jacksonville, Florida, United States, 32216 United States, Georgia Morehouse School of Medicine Atlanta, Georgia, United States, 30310 United States, Rhode Island Center for Medical Research, LLC Providence, Rhode Island, United States, 02908 Collapse << |
| NCT00204984 | High Blood Pressure | Not Applicable | Completed | - | United States, Wisconsin ... more >> University of Wisconsin Hospital & Clinics Madison, Wisconsin, United States, 53792 Collapse << |
| NCT01248169 | - | - | Completed | - | United States, Mississippi ... more >> Wiser Hospital for Women and Infants at the University of Mississippi Medical Center Jackson, Mississippi, United States, 39216 Collapse << |
| NCT02281838 | Intracerebral Hemorrhage | Phase 2 | Recruiting | - | Canada, Alberta ... more >> University of Alberta Recruiting Edmonton, Alberta, Canada, T6G 2B7 Contact: Ken S Butcher, MD, PhD 7804072171 ken.butcher@ualberta.ca Principal Investigator: Ken S Butcher, MD, PhD Canada, Ontario Ottawa Hospital Research Institute Recruiting Ottawa, Ontario, Canada, K1Y 4E9 Contact: Dar Dowlatshahi 613-761-4709 ddowlat@toh.on.ca Principal Investigator: Dar Dowlatshahi, MD Collapse << |
| NCT02046395 | Type 2 Diabetes ... more >> Hypertension Collapse << | Phase 4 | Recruiting | December 2019 | United States, Louisiana ... more >> Tulane University Health Sciences Center Recruiting New Orleans, Louisiana, United States, 70112 Contact: Bonnie L Katalenich, MPH 504-988-0200 bkatalen@tulane.edu Principal Investigator: Tina Thethi, MD, MPH Collapse << |
| NCT00963976 | Intracerebral Hemorrhage | Phase 2 | Completed | - | Canada, Alberta ... more >> University of Calgary Calgary, Alberta, Canada University of Alberta Edmonton, Alberta, Canada, T6G2B7 Grey Nuns Hospital Edmonton, Alberta, Canada, T6L 5X8 Canada, Ontario University of Ottawa Ottawa, Ontario, Canada Collapse << |
| NCT02933593 | Hypertension | Not Applicable | Withdrawn(PI withdrew the prot... more >>ocol) Collapse << | - | - |
| NCT00607477 | Treatment Induced Hypertension | Not Applicable | Terminated(Study has been term... more >>inated due to poor accrual.) Collapse << | - | United States, Illinois ... more >> University of Chicago Chicago, Illinois, United States, 60637 Collapse << |
| NCT01587313 | Healthy | Phase 1 | Completed | - | United States, New Jersey ... more >> Frontage Cinical Services Hackensack, New Jersey, United States, 07601 Collapse << |
| NCT01516346 | Heart Failure ... more >> Congestive Heart Failure Collapse << | Phase 2 | Completed | - | United States, Pennsylvania ... more >> Philadelphia VA Medical Center Philadelphia, Pennsylvania, United States, 19104 Collapse << |
| NCT03514108 | Heart Failure ... more >> Diabetes Collapse << | Phase 4 | Recruiting | September 1, 2023 | Denmark ... more >> Sygehus Sønderjylland, Aabenraa Not yet recruiting Aabenraa, Denmark Contact: Bartlomiej Jonczy Aalborg University Hospital Not yet recruiting Aalborg, Denmark Contact: Søren Vraa Aarhus University Hospital Recruiting Aarhus, Denmark Contact: Henrik Wiggers +45 40136627 henrikwiggers@dadlnet.dk Sub-Investigator: Anders Jorsal Amager Hospital Not yet recruiting Copenhagen, Denmark Contact: Margrethe Ege Olsen Bispebjerg Hospital Not yet recruiting Copenhagen, Denmark Contact: Olav Wendelbo Nielsen Gentofte Hospital Recruiting Copenhagen, Denmark Contact: Morten Schou Glostrup Hospital Not yet recruiting Copenhagen, Denmark Contact: Morten Petersen Herlev Hospital Recruiting Copenhagen, Denmark Contact: Morten Schou Hvidovre Hospital Not yet recruiting Copenhagen, Denmark Contact: Jens Hove Rigshospitalet Recruiting Copenhagen, Denmark Contact: Lars Køber Principal Investigator: Finn Gustafsson Sydvestjysk Sygehus, Esbjerg Not yet recruiting Esbjerg, Denmark Contact: Kirsten Vilain Mikkelsen Herning Hospital Not yet recruiting Herning, Denmark Contact: Morten Bøttcher Regionshospital Nordjylland, Hjørring Not yet recruiting Hjørring, Denmark Contact: Gitte Nielsen Holbæk Hospital Not yet recruiting Holbæk, Denmark Contact: Ilan Raymond Horsens Hospital Not yet recruiting Horsens, Denmark Contact: Karen Kaae Dodt Kolding Hospital Not yet recruiting Kolding, Denmark Contact: Monica Petronela Poenaru Nykøbing Falster Hospital Not yet recruiting Nykøbing Falster, Denmark Contact: Lisbeth Tingsted Odense University Hospital Not yet recruiting Odense, Denmark Contact: Mikael Kjær Poulsen Sjællands Universitetshospital, Roskilde Not yet recruiting Roskilde, Denmark Contact: Nina Pernille Gardshodn Buch Silkeborg Hospital Not yet recruiting Silkeborg, Denmark Contact: Anne Sejr Knudsen Slagelse Sygehus Not yet recruiting Slagelse, Denmark Contact: Henrik Ryde Vejle Hospital Not yet recruiting Vejle, Denmark Contact: Vibeke Brogaard Viborg Hospital Not yet recruiting Viborg, Denmark Contact: Anne Pauline Schrøder Collapse << |
| NCT01356875 | Myelodysplastic Syndrome | Phase 2 | Unknown | January 2015 | Spain ... more >> Txagorritxu Hospital Not yet recruiting Vitoria-Gasteiz, Alava, Spain, 01009 Contact: Breno Moreno de Gusmao, MD +34 945 007000 breno.morenodegusmao@osakidetza.net Collapse << |
| NCT00607477 | - | - | Terminated(Study has been term... more >>inated due to poor accrual.) Collapse << | - | - |
| NCT00575640 | Rectal Cancer | Phase 1 Phase 2 | Withdrawn(No enrollment) | - | - |
| NCT00404326 | Cervical Cancer | Phase 2 | Completed | - | Mexico ... more >> National Institute of Cancerologia Mexico City, Tlalpan, Mexico, 14080 Collapse << |
| NCT00532818 | Metastatic Cervical Cancer | Phase 3 | Unknown | December 2010 | Mexico ... more >> Instituto Nacional de Cancerologia Recruiting Mexico City, Distrito Federal, Mexico, 14080 Principal Investigator: Lucely Cetina, MD Collapse << |
| NCT02343393 | Cardio-Renal Syndrome | Phase 3 | Unknown | June 2016 | Singapore ... more >> National University Hospital, Singapore Recruiting Singapore, Singapore, 119228 Contact: Shir Lynn Lim, MBBS, MRCP, MMed shir_lynn_lim@nuhs.edu.sg Principal Investigator: Shir Lynn Lim, MBBS, MRCP, MMed National Heart Centre Singapore Not yet recruiting Singapore, Singapore, 169609 Contact: Kheng Leng David Sim, MBBS, MRCP, MS david_sim@nhcs.com.sg Principal Investigator: Kheng Leng David Sim, MBBS, MRCP, MS Changi General Hospital Not yet recruiting Singapore, Singapore, 529889 Contact: Kui Toh Gerard Leong, MBBS, MRCP, MS gerard_leong@cgh.com.sg Principal Investigator: Kui Toh Gerard Leong, MBBS, MRCP, MS Collapse << |
| NCT00395655 | Locally Advanced Breast Cancer | Phase 2 | Terminated | - | Mexico ... more >> Instituto Nacional de Cancerologia Mexico City, Tlalpan, Mexico, 14080 Collapse << |
| NCT00404508 | Refractory Solid Tumors | Phase 2 | Completed | - | Mexico ... more >> National Institute of Cancerologia Mexico City, Tlalpan, Mexico, 14080 Collapse << |
| NCT01538875 | Hypertension, Pregnancy Induce... more >>d Collapse << | Phase 3 | Completed | - | Panama ... more >> Saint Thomas Maternity Hospital Panama, Panama Collapse << |
| NCT03423810 | Polycystic Kidney Diseases | Early Phase 1 | Recruiting | May 15, 2019 | United States, Kansas ... more >> University of Kansas Medical Center Recruiting Kansas City, Kansas, United States, 66160 Collapse << |
| NCT00996060 | Lung Cancer | Phase 1 | Completed | - | United States, New Mexico ... more >> University of New Mexico Cancer Center Albuquerque, New Mexico, United States, 87106 Collapse << |
| NCT02228408 | Chronic Hemodialysis (ESRD) | Phase 4 | Recruiting | December 15, 2020 | United States, Massachusetts ... more >> Brigham & Women's Hospital Recruiting Boston, Massachusetts, United States, 02115 Principal Investigator: David Charytan, MD Collapse << |
| NCT00575978 | Breast Cancer | Phase 1 Phase 2 | Withdrawn(IRB request) | December 2009 | - |
| NCT02050529 | Hypertension, Pregnancy Induce... more >>d Hydralazine Adverse Reaction Pre-eclampsia Pre-eclampsia Superimposed Pre-existing Hypertension Collapse << | Phase 2 | Completed | - | Pakistan ... more >> Civil Hospital Karachi Karachi, Sindh, Pakistan, 74200 Collapse << |
| NCT01822808 | Acute Heart Failure ... more >> Left Ventricular Dysfunction Collapse << | Phase 3 | Unknown | July 2016 | South Africa ... more >> Hatter Institute for Cardiovascular Research in Africa Cape Town, Western Cape, South Africa, 7925 Collapse << |
| NCT00533299 | Ovarian Cancer | Phase 3 | Unknown | December 2009 | Mexico ... more >> Instituto Nacional de Cancerologia Recruiting Mexico City, Tlalpan, Mexico, 14080 Principal Investigator: Dolores Gallardo, MD Collapse << |
| NCT03608085 | Heart Failure | Not Applicable | Recruiting | May 31, 2019 | United States, Rhode Island ... more >> Ocean State Research Institute Recruiting Providence, Rhode Island, United States, 02908 Contact: Mary Ford 401-273-7100 ext 3674 Mary.Ford@va.gov Principal Investigator: Tracey H Taveira, Pharm.D. Sub-Investigator: Philip Haines, MD Sub-Investigator: Wen-Chih Wu, MD Providence VAMC Recruiting Providence, Rhode Island, United States, 02908 Contact: Melanie R Parent, Ba 401-273-7100 ext 6293 Melanie.Parent@va.gov Principal Investigator: Tracey H Taveira, Pharm.D. Collapse << |
| NCT02884011 | - | - | Completed | - | United States, Illinois ... more >> Rush Univeristy Medical Center Chicago, Illinois, United States, 60612 Collapse << |
| NCT03619317 | - | - | Recruiting | August 2020 | Denmark ... more >> University Hospital of Aarhus, Department of Cardiology Recruiting Aarhus N, Denmark, 8200 Contact: Mette Søndergaard 30130565 metast@rm.dk Contact: Steen Poulsen steen.hvitfeldt@rm.dk Collapse << |
| NCT00683696 | - | - | Terminated | - | - |
| NCT00000620 | Atherosclerosis ... more >> Cardiovascular Diseases Hypercholesterolemia Hypertension Diabetes Mellitus, Type 2 Diabetes Mellitus Coronary Disease Collapse << | Phase 3 | Completed | - | United States, Minnesota ... more >> Minneapolis Medical Research Foundation Minneapolis, Minnesota, United States, 55404 United States, New York Columbia University New York, New York, United States, 10027 United States, North Carolina Wake Forest University Winston-Salem, North Carolina, United States, 27106 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Tennessee Veterans Affairs Memphis, Tennessee, United States, 38104 United States, Washington University of Washington Seattle, Washington, United States, 98195 Canada, Ontario McMaster University Hamilton, Ontario, Canada Collapse << |
| NCT00283686 | Kidney, Polycystic | Phase 3 | Completed | - | United States, Colorado ... more >> University of Colorado Health Sciences Center Denver (Aurora), Colorado, United States, 800045 United States, Georgia Emory University School of Medicine Atlanta, Georgia, United States, 30322 United States, Kansas University of Kansas Medical Center Kansas City, Kansas, United States, 66160 United States, Massachusetts Tufts University-New England Medical Center Boston, Massachusetts, United States, 02111 Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02215 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 United States, Ohio Cleveland Clinic Foundation Cleveland, Ohio, United States, 44195 Collapse << |
| NCT00283686 | - | - | Completed | - | - |
| NCT01958801 | Horner's Syndrome | Not Applicable | Completed | - | Korea, Republic of ... more >> Daegu Catholic University Medical Center Daegu, Korea, Republic of, 705-718 Collapse << |
| NCT00000620 | - | - | Completed | - | - |
| NCT00582777 | Hypertensive Renal Disease | Phase 2 Phase 3 | Completed | - | United States, Alabama ... more >> University of Alabama Birmingham, Alabama, United States, 35233 United States, California University of Southern California Los Angeles, California, United States, 90033 Charles Drew Medical College Los Angeles, California, United States, 90059 University of California at San Diego San Diego, California, United States, 92161 United States, Florida University of Florida Gainesville, Florida, United States, 32611 University of Miami Miami, Florida, United States, 33101 United States, Georgia Emory University Atlanta, Georgia, United States, 30308 United States, Illinois University of Chicago Chicago, Illinois, United States, 60637 United States, Maryland Johns Hopkins University Baltimore, Maryland, United States, 21205 United States, Michigan University of Michigan Ann Arbor, Michigan, United States, 48106 United States, New York Lenox Hill Hospital New York, New York, United States, 10021 United States, Ohio University Hospitals of Cleveland Cleveland, Ohio, United States, 44106 Ohio State University Columbus, Ohio, United States, 43210 United States, South Carolina Medical University of South Carolina Charleston, South Carolina, United States, 29425 United States, Tennessee Vanderbilt University Nashville, Tennessee, United States, 37232 United States, Texas Univesity of Texas Southwestern Medical Center at Dallas Dallas, Texas, United States, 75390 Collapse << |
| NCT00661895 | Hypertension | Phase 4 | Completed | - | United States, Nebraska ... more >> Creighton Community Health Center Omaha, Nebraska, United States, 68104 Collapse << |
| NCT00661895 | - | - | Completed | - | - |
| NCT03616730 | - | - | Not yet recruiting | December 30, 2020 | - |
| NCT00716079 | Intracerebral Hemorrhage ... more >> Stroke Hypertension Collapse << | Not Applicable | Completed | - | - |
| NCT00683696 | Heart Failure ... more >> Ventricular Dyssynchrony Collapse << | Phase 2 Phase 3 | Terminated | - | - |
| NCT01422616 | Ischemic Stroke ... more >> High Blood Pressure Collapse << | Phase 3 | Recruiting | February 2019 | Australia, New South Wales ... more >> Royal Prince Alfred Hospital Recruiting Sydney, New South Wales, Australia, 2050 Contact: Craig S Anderson, MD +61 2 933 4500 canderson@georgeinstitute.org.au Collapse << |
| NCT00226096 | CVA (Cerebrovascular Accident)... more >> Cerebral Hemorrhage Intracranial Hemorrhages Collapse << | Not Applicable | Completed | - | Australia, New South Wales ... more >> Concord Hospital Concord, New South Wales, Australia, 2138 Gosford Hospital Gosford, New South Wales, Australia, 2250 St George Hospital Kogarah, New South Wales, Australia, 2217 John Hunter Hospital Newcastle, New South Wales, Australia, 2310 St Vincent's Hospital Sydney, New South Wales, Australia, 2010 Royal Prince Alfred Hospital Sydney, New South Wales, Australia, 2050 Westmead Hospital Westmead, New South Wales, Australia, 2145 Australia, South Australia Royal Adelaide Hospital Adelaide, South Australia, Australia, 5000 Australia, Victoria Royal Melbourne Hospital Melbourne, Victoria, Australia, 3050 St Vincent's Hospital Melbourne, Victoria, Australia, 3065 Box Hill Hospital Melbourne, Victoria, Australia, 3128 Alfred Hospital Melbourne, Victoria, Australia, 3181 Austin Health Melbourne, Victoria, Australia Monash Medical Centre Melbourne, Victoria, Australia Australia, Western Australia Sir Charles Gairdner Hospital Perth, Western Australia, Australia, 6009 China Regional Coordinating Centre: Peking University First Hospital Beijing, China, 100034 Hospitals in China, c/o The George Institute China Beijing, China Regional Coordinating Centre: Centre for Epidemiological Studies and Clinical Trials, Ruijin Hospital, Shanghai Institute of Hypertension, Shanghai Second Medical University Shanghai, China, 200025 New Zealand North Shore Hospital Auckland, New Zealand Christchurch Hospital Christchurch, New Zealand Collapse << |
| NCT00512759 | Acute Heart Failure | Phase 4 | Active, not recruiting | December 2019 | Brazil ... more >> Hospital Sao Paolo São Paulo, Brazil, 04024-002 Bulgaria 5-th Multifunctional Hospital for Active Treatment Sofia, Bulgaria National Transport Hospital "Tsar Boris III" Sofia, Bulgaria University Hospital "Tsaritsa Joanna-ISUL" Sofia, Bulgaria Germany University Hospital Mainz Mainz, Germany, 55131 Nuremberg Hospital Nuremberg, Germany, 90419 Spain Hospital Universitari Germans Trias i Pujol Badalona, Spain, 08916 Hospital de la Santa Creu i Sant Pau Barcelona, Spain, 08041 Switzerland University Hospital Basel Basel, BS, Switzerland, 4031 Kantonsspital Aarau Aarau, Switzerland, 5001 Kantonsspital Luzern Luzern, Switzerland, 6000 Kantonsspital St. Gallen St. Gallen, Switzerland, 9007 Collapse << |
| NCT03147092 | Hypertension ... more >>Blood Pressure Collapse << | Early Phase 1 | Not yet recruiting | June 30, 2021 | - |
| NCT00952081 | Hypertension ... more >>Brain Tumor Epilepsy Collapse << | Phase 4 | Completed | - | United States, New York ... more >> NYU Langone Medical Center, Department of Anesthesiology New York, New York, United States, 10016 Collapse << |
| NCT00716079 | - | - | Completed | - | - |
| NCT02620384 | Acute Decompensated Heart Fail... more >>ure Collapse << | Phase 3 | Completed | - | United States, Ohio ... more >> Aultman Health Foundation Canton, Ohio, United States, 44710 Collapse << |
| NCT00952081 | - | - | Completed | - | - |
| NCT01041963 | Continuous Ambulatory Peritone... more >>al Dialysis Collapse << | Phase 4 | Unknown | September 2010 | Thailand ... more >> Chulalongkorn university Recruiting Bangkok, Thailand, 10330 Contact: Talerngsak Kanjanabuch, Assist. Prf. 662-256-4321 ext 211 golfnephro@yahoo.com Principal Investigator: Talerngsak Kanjanabuch, Assist. Prf. Sub-Investigator: Wassawon Wontanatawatot, MD Collapse << |
| NCT02305095 | - | - | Recruiting | June 2019 | - |
| NCT00684489 | Hypertension | Not Applicable | Completed | - | - |
| NCT02592499 | End-stage Heart Failure | Not Applicable | Recruiting | December 2022 | Sweden ... more >> Sahlgrenska Univesitetssjukhustet, Transplantationscentrum Recruiting Gothenburg, Sweden, 41234 Contact: Göran Dellgren +46 31-342 88 63 goran.dellgren@vgregion.se Linköping Univ Hospital Recruiting Linköping, Sweden Contact: Peter Wodlin, MD Skåne University Hospital Recruiting Lund, Sweden Contact: Oscar Braun, MD Karolinska Univ Hospital Recruiting Stockholm, Sweden Contact: Lars Lund, MD Univ Hospital of Umeå Recruiting Umeå, Sweden Contact: Krister Lindmark, MD Uppsala Univ Hospital Recruiting Uppsala, Sweden Contact: Ola Vedin, MD Örebro Univ Hospital Recruiting Örebro, Sweden Contact: Barna Szado, MD Collapse << |
| NCT00599235 | Hypertension | Not Applicable | Completed | - | United Kingdom ... more >> University of Edinburgh - Western General Hospital Edinburgh, United Kingdom, EH4 2XU Collapse << |
| NCT00204984 | High Blood Pressure | Not Applicable | Completed | - | United States, Wisconsin ... more >> University of Wisconsin Hospital & Clinics Madison, Wisconsin, United States, 53792 Collapse << |
| NCT03168529 | Heart Failure | Phase 4 | Recruiting | June 30, 2020 | United States, Michigan ... more >> Wayne State University Recruiting Detroit, Michigan, United States, 48201 Contact: Phillip D Levy, MD, MPH 313-577-1214 plevy@med.wayne.edu Contact: Patrick Medado 3137454621 pbmedado@med.wayne.edu Henry Ford Hospital Not yet recruiting Detroit, Michigan, United States, 48202 Contact: David E Lanfear, MD, MS 313-916-5620 DLANFEA1@hfhs.org Contact: Karen Leszczynski, RN 3139163502 Kleszcz2@hfhs.org Collapse << |
| NCT00772499 | Hypertension | Phase 4 | Completed | - | United States, North Carolina ... more >> Wake Forest University Baptist Medical Center Winston-Salem, North Carolina, United States, 27157 Collapse << |
| NCT00000499 | Cardiovascular Diseases ... more >> Heart Diseases Hypertension Vascular Diseases Collapse << | Phase 2 | Completed | - | - |
| NCT02446652 | Cervical Cancer | Phase 3 | Unknown | August 2018 | Mexico ... more >> National Institute of Cancerology Not yet recruiting Mexico City, DF, Mexico, 14080 Contact: Lucely Cetina, MD, MSc +52 555 628 0400 ext 56101 micuentalucely@yahoo.com Collapse << |
| NCT02281838 | Intracerebral Hemorrhage | Phase 2 | Recruiting | - | Canada, Alberta ... more >> University of Alberta Recruiting Edmonton, Alberta, Canada, T6G 2B7 Contact: Ken S Butcher, MD, PhD 7804072171 ken.butcher@ualberta.ca Principal Investigator: Ken S Butcher, MD, PhD Canada, Ontario Ottawa Hospital Research Institute Recruiting Ottawa, Ontario, Canada, K1Y 4E9 Contact: Dar Dowlatshahi 613-761-4709 ddowlat@toh.on.ca Principal Investigator: Dar Dowlatshahi, MD Collapse << |
| NCT01587313 | Healthy | Phase 1 | Completed | - | United States, New Jersey ... more >> Frontage Cinical Services Hackensack, New Jersey, United States, 07601 Collapse << |
| NCT00223717 | Hypertension | Phase 1 | Completed | - | United States, Tennessee ... more >> Vanderbilt University Nashville, Tennessee, United States, 37232 Collapse << |
| NCT02046395 | Type 2 Diabetes ... more >> Hypertension Collapse << | Phase 4 | Recruiting | December 2019 | United States, Louisiana ... more >> Tulane University Health Sciences Center Recruiting New Orleans, Louisiana, United States, 70112 Contact: Bonnie L Katalenich, MPH 504-988-0200 bkatalen@tulane.edu Principal Investigator: Tina Thethi, MD, MPH Collapse << |
| NCT01255475 | Heart Failure ... more >> Cardiac Failure Congestive Heart Failure Collapse << | Phase 2 Phase 3 | Completed | - | Brazil ... more >> Heart Institute (InCor) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo São Paulo, SP, Brazil, 05403000 Collapse << |
| NCT02522208 | Heart Failure | Phase 1 | Completed | - | United States, Alabama ... more >> Pinnacle Research Group, LLC Anniston, Alabama, United States, 36207 United States, Florida Linfritz Research Institue Inc Coral Gables, Florida, United States, 33134 Jacksonville Center for Clinical Research Jacksonville, Florida, United States, 32216 United States, Georgia Morehouse School of Medicine Atlanta, Georgia, United States, 30310 United States, Rhode Island Center for Medical Research, LLC Providence, Rhode Island, United States, 02908 Collapse << |
| NCT00963976 | Intracerebral Hemorrhage | Phase 2 | Completed | - | Canada, Alberta ... more >> University of Calgary Calgary, Alberta, Canada University of Alberta Edmonton, Alberta, Canada, T6G2B7 Grey Nuns Hospital Edmonton, Alberta, Canada, T6L 5X8 Canada, Ontario University of Ottawa Ottawa, Ontario, Canada Collapse << |
| NCT01248169 | - | - | Completed | - | United States, Mississippi ... more >> Wiser Hospital for Women and Infants at the University of Mississippi Medical Center Jackson, Mississippi, United States, 39216 Collapse << |
| NCT00607477 | - | - | Terminated(Study has been term... more >>inated due to poor accrual.) Collapse << | - | - |
| NCT03514108 | Heart Failure ... more >> Diabetes Collapse << | Phase 4 | Recruiting | September 1, 2023 | Denmark ... more >> Sygehus Sønderjylland, Aabenraa Not yet recruiting Aabenraa, Denmark Contact: Bartlomiej Jonczy Aalborg University Hospital Not yet recruiting Aalborg, Denmark Contact: Søren Vraa Aarhus University Hospital Recruiting Aarhus, Denmark Contact: Henrik Wiggers +45 40136627 henrikwiggers@dadlnet.dk Sub-Investigator: Anders Jorsal Amager Hospital Not yet recruiting Copenhagen, Denmark Contact: Margrethe Ege Olsen Bispebjerg Hospital Not yet recruiting Copenhagen, Denmark Contact: Olav Wendelbo Nielsen Gentofte Hospital Recruiting Copenhagen, Denmark Contact: Morten Schou Glostrup Hospital Not yet recruiting Copenhagen, Denmark Contact: Morten Petersen Herlev Hospital Recruiting Copenhagen, Denmark Contact: Morten Schou Hvidovre Hospital Not yet recruiting Copenhagen, Denmark Contact: Jens Hove Rigshospitalet Recruiting Copenhagen, Denmark Contact: Lars Køber Principal Investigator: Finn Gustafsson Sydvestjysk Sygehus, Esbjerg Not yet recruiting Esbjerg, Denmark Contact: Kirsten Vilain Mikkelsen Herning Hospital Not yet recruiting Herning, Denmark Contact: Morten Bøttcher Regionshospital Nordjylland, Hjørring Not yet recruiting Hjørring, Denmark Contact: Gitte Nielsen Holbæk Hospital Not yet recruiting Holbæk, Denmark Contact: Ilan Raymond Horsens Hospital Not yet recruiting Horsens, Denmark Contact: Karen Kaae Dodt Kolding Hospital Not yet recruiting Kolding, Denmark Contact: Monica Petronela Poenaru Nykøbing Falster Hospital Not yet recruiting Nykøbing Falster, Denmark Contact: Lisbeth Tingsted Odense University Hospital Not yet recruiting Odense, Denmark Contact: Mikael Kjær Poulsen Sjællands Universitetshospital, Roskilde Not yet recruiting Roskilde, Denmark Contact: Nina Pernille Gardshodn Buch Silkeborg Hospital Not yet recruiting Silkeborg, Denmark Contact: Anne Sejr Knudsen Slagelse Sygehus Not yet recruiting Slagelse, Denmark Contact: Henrik Ryde Vejle Hospital Not yet recruiting Vejle, Denmark Contact: Vibeke Brogaard Viborg Hospital Not yet recruiting Viborg, Denmark Contact: Anne Pauline Schrøder Collapse << |
| NCT01516346 | Heart Failure ... more >> Congestive Heart Failure Collapse << | Phase 2 | Completed | - | United States, Pennsylvania ... more >> Philadelphia VA Medical Center Philadelphia, Pennsylvania, United States, 19104 Collapse << |
| NCT00404508 | Refractory Solid Tumors | Phase 2 | Completed | - | Mexico ... more >> National Institute of Cancerologia Mexico City, Tlalpan, Mexico, 14080 Collapse << |
| NCT00607477 | Treatment Induced Hypertension | Not Applicable | Terminated(Study has been term... more >>inated due to poor accrual.) Collapse << | - | United States, Illinois ... more >> University of Chicago Chicago, Illinois, United States, 60637 Collapse << |
| NCT02933593 | Hypertension | Not Applicable | Withdrawn(PI withdrew the prot... more >>ocol) Collapse << | - | - |
| NCT00404326 | Cervical Cancer | Phase 2 | Completed | - | Mexico ... more >> National Institute of Cancerologia Mexico City, Tlalpan, Mexico, 14080 Collapse << |
| NCT00575640 | Rectal Cancer | Phase 1 Phase 2 | Withdrawn(No enrollment) | - | - |
| NCT01356875 | Myelodysplastic Syndrome | Phase 2 | Unknown | January 2015 | Spain ... more >> Txagorritxu Hospital Not yet recruiting Vitoria-Gasteiz, Alava, Spain, 01009 Contact: Breno Moreno de Gusmao, MD +34 945 007000 breno.morenodegusmao@osakidetza.net Collapse << |
| NCT01538875 | Hypertension, Pregnancy Induce... more >>d Collapse << | Phase 3 | Completed | - | Panama ... more >> Saint Thomas Maternity Hospital Panama, Panama Collapse << |
| NCT00395655 | Locally Advanced Breast Cancer | Phase 2 | Terminated | - | Mexico ... more >> Instituto Nacional de Cancerologia Mexico City, Tlalpan, Mexico, 14080 Collapse << |
| NCT00532818 | Metastatic Cervical Cancer | Phase 3 | Unknown | December 2010 | Mexico ... more >> Instituto Nacional de Cancerologia Recruiting Mexico City, Distrito Federal, Mexico, 14080 Principal Investigator: Lucely Cetina, MD Collapse << |
| NCT00996060 | Lung Cancer | Phase 1 | Completed | - | United States, New Mexico ... more >> University of New Mexico Cancer Center Albuquerque, New Mexico, United States, 87106 Collapse << |
| NCT00533299 | Ovarian Cancer | Phase 3 | Unknown | December 2009 | Mexico ... more >> Instituto Nacional de Cancerologia Recruiting Mexico City, Tlalpan, Mexico, 14080 Principal Investigator: Dolores Gallardo, MD Collapse << |
| NCT02343393 | Cardio-Renal Syndrome | Phase 3 | Unknown | June 2016 | Singapore ... more >> National University Hospital, Singapore Recruiting Singapore, Singapore, 119228 Contact: Shir Lynn Lim, MBBS, MRCP, MMed shir_lynn_lim@nuhs.edu.sg Principal Investigator: Shir Lynn Lim, MBBS, MRCP, MMed National Heart Centre Singapore Not yet recruiting Singapore, Singapore, 169609 Contact: Kheng Leng David Sim, MBBS, MRCP, MS david_sim@nhcs.com.sg Principal Investigator: Kheng Leng David Sim, MBBS, MRCP, MS Changi General Hospital Not yet recruiting Singapore, Singapore, 529889 Contact: Kui Toh Gerard Leong, MBBS, MRCP, MS gerard_leong@cgh.com.sg Principal Investigator: Kui Toh Gerard Leong, MBBS, MRCP, MS Collapse << |
| NCT03423810 | Polycystic Kidney Diseases | Early Phase 1 | Recruiting | May 15, 2019 | United States, Kansas ... more >> University of Kansas Medical Center Recruiting Kansas City, Kansas, United States, 66160 Collapse << |
| NCT01822808 | Acute Heart Failure ... more >> Left Ventricular Dysfunction Collapse << | Phase 3 | Unknown | July 2016 | South Africa ... more >> Hatter Institute for Cardiovascular Research in Africa Cape Town, Western Cape, South Africa, 7925 Collapse << |
| NCT00575978 | Breast Cancer | Phase 1 Phase 2 | Withdrawn(IRB request) | December 2009 | - |
| NCT02050529 | Hypertension, Pregnancy Induce... more >>d Hydralazine Adverse Reaction Pre-eclampsia Pre-eclampsia Superimposed Pre-existing Hypertension Collapse << | Phase 2 | Completed | - | Pakistan ... more >> Civil Hospital Karachi Karachi, Sindh, Pakistan, 74200 Collapse << |
| NCT02228408 | Chronic Hemodialysis (ESRD) | Phase 4 | Recruiting | December 15, 2020 | United States, Massachusetts ... more >> Brigham & Women's Hospital Recruiting Boston, Massachusetts, United States, 02115 Principal Investigator: David Charytan, MD Collapse << |
