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CAS No.: 112559-91-8
Synonyms: Itraconazole metabolite Hydroxy Itraconazole;R-63373;OH-ITZ
Hydroxy itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT02633709 | Spinal Muscular Atrophy | Phase 1 | Completed | - | Netherlands ... more >> Pra International Group B.V Groningen, Netherlands, 9728 NZ Collapse << |
NCT02093728 | Solid Tumours | Phase 1 | Completed | - | United States, Kansas ... more >> Research Site Overland Park, Kansas, United States Collapse << |
NCT02157883 | Advanced Non Small Cell Lung C... more >>ancer Advanced (Inoperable) Non Small Cell Lung Cancer Collapse << | Phase 1 | Active, not recruiting | December 31, 2018 | United States, California ... more >> Research Site San Diego, California, United States, 92123 United States, Ohio Research Site Cleveland, Ohio, United States, 44106-4950 Belgium Research Site Edegem, Belgium, 2650 Research Site Gent, Belgium, 9000 Korea, Republic of Research Site Seongnam-si, Korea, Republic of, 13620 Research Site Seoul, Korea, Republic of, 03080 Research Site Seoul, Korea, Republic of, 03722 Research Site Seoul, Korea, Republic of, 06351 Research Site Seoul, Korea, Republic of, 138-736 Netherlands Research Site Amsterdam, Netherlands, 1066 CX Research Site Maastricht, Netherlands, 6229 HX Research Site Rotterdam, Netherlands, 3015 CE Taiwan Research Site Taipei, Taiwan, 10002 Research Site Taipei, Taiwan, 11217 United Kingdom Research Site London, United Kingdom, SE1 9RT Research Site Manchester, United Kingdom, M20 4BX Collapse << |
实验方案
技术信息
CAS号 | 112559-91-8 | 储存条件 |
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分子式 | C35H38Cl2N8O5 | 运输 | 蓝冰 | |
分子量 | 721.63 | 别名 | Itraconazole metabolite Hydroxy Itraconazole;R-63373;OH-ITZ;hydroxy-ITZ;Hydroxyitraconazole;羟基伊曲康唑 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02633709 | Spinal Muscular Atrophy | Phase 1 | Completed | - | Netherlands ... more >> Pra International Group B.V Groningen, Netherlands, 9728 NZ Collapse << |
NCT02093728 | Solid Tumours | Phase 1 | Completed | - | United States, Kansas ... more >> Research Site Overland Park, Kansas, United States Collapse << |
NCT02157883 | Advanced Non Small Cell Lung C... more >>ancer Advanced (Inoperable) Non Small Cell Lung Cancer Collapse << | Phase 1 | Active, not recruiting | December 31, 2018 | United States, California ... more >> Research Site San Diego, California, United States, 92123 United States, Ohio Research Site Cleveland, Ohio, United States, 44106-4950 Belgium Research Site Edegem, Belgium, 2650 Research Site Gent, Belgium, 9000 Korea, Republic of Research Site Seongnam-si, Korea, Republic of, 13620 Research Site Seoul, Korea, Republic of, 03080 Research Site Seoul, Korea, Republic of, 03722 Research Site Seoul, Korea, Republic of, 06351 Research Site Seoul, Korea, Republic of, 138-736 Netherlands Research Site Amsterdam, Netherlands, 1066 CX Research Site Maastricht, Netherlands, 6229 HX Research Site Rotterdam, Netherlands, 3015 CE Taiwan Research Site Taipei, Taiwan, 10002 Research Site Taipei, Taiwan, 11217 United Kingdom Research Site London, United Kingdom, SE1 9RT Research Site Manchester, United Kingdom, M20 4BX Collapse << |
NCT02653872 | - | - | Completed | - | - |
NCT02370615 | Japanese Healthy Adult Males | Phase 1 | Completed | - | Japan ... more >> Osaka-shi, Osaka, Japan Collapse << |
NCT03209648 | Healthy Participants | Phase 1 | Completed | - | United Kingdom ... more >> Covance Clinical Research Unit Ltd. Leeds, United Kingdom, LS2 9LH Collapse << |
NCT01913379 | Healthy Subjects ... more >> Pharmacokinetics Drug-Drug Interaction Collapse << | Phase 1 | Completed | - | France ... more >> SGS Paris, France, 75015 Collapse << |
NCT02653872 | Healthy Subjects | Phase 1 | Completed | - | United Kingdom ... more >> Research Site London, United Kingdom Collapse << |
NCT02259010 | Advanced Solid Tumors ... more >> Relapsed/Refractory Lymphoma Collapse << | Phase 1 | Unknown | April 2016 | United States, Missouri ... more >> St. Louis, Missouri, United States United States, Oklahoma Oklahoma City, Oklahoma, United States United States, Tennessee Germantown, Tennessee, United States United States, Texas Dallas, Texas, United States Collapse << |
NCT02370615 | - | - | Completed | - | - |
NCT03624959 | Healthy Volunteer | Phase 1 | Recruiting | April 15, 2019 | United States, Texas ... more >> PPD Phase 1 Clinic Recruiting Austin, Texas, United States, 78744 Collapse << |
NCT02157883 | - | - | Active, not recruiting | - | - |
NCT02122692 | Healthy Volunteers | Phase 1 | Completed | - | France ... more >> FR801 Rennes, France, 35042 Collapse << |
NCT02175407 | Pharmacokinetics ... more >> DDI (Drug-Drug Interaction) Healthy Subjects Collapse << | Phase 1 | Completed | - | Germany ... more >> PAREXEL International GmbH Berlin, Germany, 14050 Collapse << |
NCT02328443 | Healthy | Phase 1 | Completed | - | - |
NCT02838264 | Healthy | Phase 1 | Completed | - | Belgium ... more >> Pfizer Clinical Research Unit Brussels, Belgium, B-1070 Collapse << |
NCT02706535 | Drug Interactions | Phase 1 | Completed | - | United States, Maryland ... more >> GSK Investigational Site Baltimore, Maryland, United States, 21225 Collapse << |
NCT03579719 | Healthy Volunteers | Phase 1 | Recruiting | November 10, 2018 | Netherlands ... more >> Pra International Group B.V Recruiting Groningen, Netherlands, 9728 NZ Collapse << |
NCT02975037 | Healthy | Phase 4 | Unknown | April 2017 | - |
NCT02698267 | Neuropathic Pain | Phase 1 | Completed | - | United Kingdom ... more >> Research Site Leeds, United Kingdom, LS2 9LH Collapse << |
NCT02513446 | Healthy | Phase 1 | Completed | - | Germany ... more >> 1320.20.1 Boehringer Ingelheim Investigational Site Biberach, Germany Collapse << |
NCT02085967 | Healthy Subjects | Phase 1 | Completed | - | United States, Texas ... more >> PPD Development LLC Austin, Texas, United States, 78744 Collapse << |
NCT02055703 | Healthy Subjects | Phase 1 | Completed | - | United States, Texas ... more >> WCT Early Development San Antonio, Texas, United States, 78217 Collapse << |
NCT01787331 | - | - | Completed | - | - |
NCT02230033 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
NCT03222310 | Healthy Volunteers | Phase 1 | Completed | - | United States, Texas ... more >> Covance Research Unit - Dallas Dallas, Texas, United States, 75247 Collapse << |
NCT02831972 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States, 85283 Collapse << |
NCT01214941 | Pharmacokinetics ... more >> Pharmacodynamics Collapse << | Phase 4 | Completed | - | Finland ... more >> Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, Turku University and Turku University Hospital Turku, Finland, 20521 Collapse << |
NCT01929876 | Healthy Participants | Phase 1 | Completed | - | United States, Texas ... more >> Dallas, Texas, United States, 75247 Collapse << |
NCT01409018 | Pediatric, Cancer | Phase 1 | Completed | - | Korea, Republic of ... more >> Seoul National University Hospital Seoul, Chongno-gu, Korea, Republic of Collapse << |
NCT03259542 | Drug Interaction Potentiation ... more >> Healthy Collapse << | Phase 1 | Completed | - | United States, Florida ... more >> SeaView Research Miami, Florida, United States, 33126 Collapse << |
NCT02130661 | Alzheimer's Disease | Phase 1 | Withdrawn | January 2018 | - |
NCT01787331 | Prostate Adenocarcinoma ... more >> Recurrent Prostate Carcinoma Stage I Prostate Adenocarcinoma AJCC v7 Stage II Prostate Adenocarcinoma AJCC v7 Stage III Prostate Adenocarcinoma AJCC v7 Collapse << | Phase 2 | Completed | - | United States, California ... more >> University of California, San Francisco San Francisco, California, United States, 94115 Collapse << |
NCT01929876 | - | - | Completed | - | - |
NCT03512548 | Healthy | Phase 1 | Recruiting | December 31, 2018 | United States, Arizona ... more >> Celerion Recruiting Tempe, Arizona, United States, 85283 Collapse << |
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