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CAS No.: 500715-03-7
Synonyms: PA-6
IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. IK1 inhibitor PA-6 (PA-6) elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia[1][2][3].
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技术信息
CAS号 | 500715-03-7 | 储存条件 |
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分子式 | C31H32N4O2 | 运输 | 蓝冰 | |
分子量 | 492.61 | 别名 | PA-6 |
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