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CAS No.: 53-86-1
Synonyms: Indometacin;Indocin;吲哚美辛
Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively, used to reduce fever, pain, stiffness, and swelling.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT00811057 | Preterm Labor | Not Applicable | Completed | - | United States, Mississippi ... more >> The Winfred L. Wiser Hospital for Women and Infants at the University of Mississippi Medical Center Jackson, Mississippi, United States, 39216 Collapse << |
NCT00811057 | - | - | Completed | - | - |
NCT02609386 | Squamous Cell Carcinoma of the... more >> Oral Cavity Collapse << | Phase 2 | Active, not recruiting | December 2019 | United States, Arizona ... more >> Banner University Medical Center Tucson, Arizona, United States, 85742 United States, Arkansas University of Arkansas For Medical Sciences Little Rock, Arkansas, United States, 72205 United States, California USC Norris Comprehensive Cancer Center Los Angeles, California, United States, 90033 Stanford University Medical Center Stanford, California, United States, 94305 United States, Georgia Emory University - Winship Cancer Center Atlanta, Georgia, United States, 30322 United States, Kentucky University of Kentucky Lexington, Kentucky, United States, 40506 United States, Michigan University of Michigan Ann Arbor, Michigan, United States, 48109 United States, Nebraska Nebraska Methodist Hospital Omaha, Nebraska, United States, 68114 United States, New York Monter Cancer Center - North Shore LIJ New Hyde Park, New York, United States, 11040 Lenox Hill Hospital New York, New York, United States, 10075 United States, Oklahoma University of Oklahoma Oklahoma City, Oklahoma, United States, 73104 United States, Oregon Providence Cancer Center Portland, Oregon, United States, 97209 United States, Pennsylvania Hospital of The University of Pennsylvania Philadelphia, Pennsylvania, United States, 19106 Brazil Hospital Erasto Gaertner Curitiba, Brazil Instituto Goiano de Oncologia e Hematologia (INGOH) Goiânia, Brazil Instituto do Câncer de Londrina Londrina, Brazil Instituto Nacional do Cancer (INCA) Rio de Janeiro, Brazil Hospital de Base de São José do Rio Preto São José do Rio Prêto, Brazil Instituto Brasileiro de Controle do Câncer São Paulo, Brazil Instituto do Cancer do Estado de São Paulo - ICESP São Paulo, Brazil Canada Sunnybrook Research Institute Toronto, Canada United Kingdom Queen Elizabeth University Hospital Glasgow Glasgow, United Kingdom Collapse << |
实验方案
技术信息
CAS号 | 53-86-1 | 储存条件 |
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分子式 | C19H16ClNO4 | 运输 | 蓝冰 | |||||||||||
分子量 | 357.79 | 别名 | Indometacin;Indocin;吲哚美辛 | |||||||||||
溶解度 |
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动物实验配方 |
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Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
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143982 cells | - | Function assay | - | In vitro inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2) in 143982 cells, IC50=9 nM | 12877584 |
A549 cells | 10 μM | Function assay | - | Inhibition of mPGES1 in human A549 cells assessed as inhibition of IL-1-beta-induced PGE2 formation at 10 uM by cell-intact assay | 19053751 |
CHO cells | - | Function assay | - | In vitro inhibitory potency against human COX-1 in stably transfected chinese hamster ovary (CHO) cells, IC50=18 nM | 10576684 |
HeLa cells | - | Function assay | 20 mins | Agonist activity at androgen receptor (unknown origin) expressed in HeLa cells co-expressing PSA-(ARE)4-Luc13 assessed as induction of DHT-induced luciferase activity after 20 mins by luciferase reporter gene assay, EC50=0.14 nM | 23432095 |
HepG2 cells | 100 μM | Function assay | - | Inhibition of MRP1-mediated doxorubicin efflux in doxorubicin resistant human HepG2 cells at 100 uM by flow cytometry | 20455578 |
human 2008 cells | - | Function assay | - | Inhibition of human MRP1 in human 2008 cells, IC50=12 μM | 18707884 |
J774 cells | - | Function assay | - | In vitro inhibitory activity against Prostaglandin G/H synthase 1 in murine J774 cells, IC50=2 nM | 15857149 |
LNCAP cells | 30 μM | Function assay | 48 h | Inhibition of AKR1C3 (unknown origin)-mediated testosterone-17beta-glucuronide formation expressed in human LNCAP cells at 30 uM after 48 hrs in presence of 4-androstene-3,17-dione | 23432095 |
MDA-MB-231 cells | 100 μM | Function assay | 30 mins | Irreversible inhibition of COX-1 in human MDA-MB-231 cells assessed as inhibition of arachidonic acid-induced PGE2 formation at 100 uM incubated for 30 mins followed by compound washout measured 30 mins post arachidonic acid challenge by radioimmunoassay | 23651359 |
mouse BV2 cells | - | Function assay | 24 h | Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay, IC50=7.1 μM | 24042007 |
mouse BV2 cells | - | Cytotoxicity assay | 24 h | Cytotoxicity against mouse BV2 cells assessed as maximum non-toxic concentration after 24 hrs by MTT assay | 23711917 |
mouse RAW264.7 cells | - | Function assay | 24 h | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess assay, IC50=1.25 μM | 24806310 |
rat synovial cells | - | Function assay | - | In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells, IC50=2.9 nM | 10821716 |
RBL-1 cell line | - | Function assay | - | Inhibition of Prostaglandin G/H synthase in intact RBL-1 cell line, IC50=0.5 μM | 2115586 |
SF-9 insect cells | - | Function assay | 20 Mins | Inhibition of human COX2 expressed in SF-9 insect cells assessed as conversion of [14C]-arachidonic acid to [14C]-prostaglandins preincubated for 20 mins by thin-layer chromatography analysis, IC50=0.75 μM | 21524587 |
THP1 cells | 100 μM | Function assay | 30 mins | Irreversible inhibition of COX-1 in human THP1 cells assessed as inhibition of arachidonic acid-induced TXB2 formation at 100 uM incubated for 30 mins followed by compound washout measured 30 mins post arachidonic acid challenge by radioimmunoassay | 23651359 |
U-937 cells | - | Function assay | - | In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cells, IC50=2 nM | 12877584 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00811057 | Preterm Labor | Not Applicable | Completed | - | United States, Mississippi ... more >> The Winfred L. Wiser Hospital for Women and Infants at the University of Mississippi Medical Center Jackson, Mississippi, United States, 39216 Collapse << |
NCT00811057 | - | - | Completed | - | - |
NCT02609386 | Squamous Cell Carcinoma of the... more >> Oral Cavity Collapse << | Phase 2 | Active, not recruiting | December 2019 | United States, Arizona ... more >> Banner University Medical Center Tucson, Arizona, United States, 85742 United States, Arkansas University of Arkansas For Medical Sciences Little Rock, Arkansas, United States, 72205 United States, California USC Norris Comprehensive Cancer Center Los Angeles, California, United States, 90033 Stanford University Medical Center Stanford, California, United States, 94305 United States, Georgia Emory University - Winship Cancer Center Atlanta, Georgia, United States, 30322 United States, Kentucky University of Kentucky Lexington, Kentucky, United States, 40506 United States, Michigan University of Michigan Ann Arbor, Michigan, United States, 48109 United States, Nebraska Nebraska Methodist Hospital Omaha, Nebraska, United States, 68114 United States, New York Monter Cancer Center - North Shore LIJ New Hyde Park, New York, United States, 11040 Lenox Hill Hospital New York, New York, United States, 10075 United States, Oklahoma University of Oklahoma Oklahoma City, Oklahoma, United States, 73104 United States, Oregon Providence Cancer Center Portland, Oregon, United States, 97209 United States, Pennsylvania Hospital of The University of Pennsylvania Philadelphia, Pennsylvania, United States, 19106 Brazil Hospital Erasto Gaertner Curitiba, Brazil Instituto Goiano de Oncologia e Hematologia (INGOH) Goiânia, Brazil Instituto do Câncer de Londrina Londrina, Brazil Instituto Nacional do Cancer (INCA) Rio de Janeiro, Brazil Hospital de Base de São José do Rio Preto São José do Rio Prêto, Brazil Instituto Brasileiro de Controle do Câncer São Paulo, Brazil Instituto do Cancer do Estado de São Paulo - ICESP São Paulo, Brazil Canada Sunnybrook Research Institute Toronto, Canada United Kingdom Queen Elizabeth University Hospital Glasgow Glasgow, United Kingdom Collapse << |
NCT02361645 | Vitreous Inflammation | Phase 3 | Completed | - | - |
NCT00000494 | Cardiovascular Diseases ... more >> Defect, Congenital Heart Ductus Arteriosus, Patent Heart Diseases Collapse << | Phase 3 | Completed | - | - |
NCT02603822 | Impaired Small Intestinal Perm... more >>eability Collapse << | Phase 1 | Completed | - | United States, Minnesota ... more >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 Collapse << |
NCT00549549 | Arthritis, Gouty | Phase 3 | Completed | - | - |
NCT01848665 | Healthy Males ... more >> Neuromuscular Function Collapse << | Phase 4 | Completed | - | Canada, Ontario ... more >> Brock University St Catharines, Ontario, Canada, L2S 3A1 Collapse << |
NCT00549549 | - | - | Completed | - | - |
NCT00002535 | Melanoma (Skin) | Phase 2 | Completed | - | United States, Wisconsin ... more >> St. Luke's Medical Center Milwaukee, Wisconsin, United States, 53215 Collapse << |
NCT01830335 | Healthy Males ... more >> Neuromuscular Function Collapse << | Phase 4 | Completed | - | Canada, Ontario ... more >> Brock University St Catharines, Ontario, Canada, L2S 3A1 Collapse << |
NCT01280006 | Obstructive Sleep Apnea ... more >> Hypertension Cardiovascular Diseases Stroke Collapse << | Phase 1 Phase 2 | Completed | - | Canada, Alberta ... more >> The Laboratory of Human Cerebrovascular Physiology, HMRB 209 & HMRB 230, University of Calgary Calgary, Alberta, Canada, T2N 4N1 Collapse << |
NCT03708458 | Post-ERCP Pancreatitis | Phase 4 | Recruiting | December 15, 2018 | Romania ... more >> Institute of Gastroenterology and Hepatology - St. Spiridon County Clinical Emergency Hospital of Iași Recruiting Iași, Romania, cod 700111 Contact: GHEORGHE BALAN, PROFESSOR +40732402845 drbalanumfiasi@yahoo.com Collapse << |
NCT01742689 | Renal Colic P... more >>ain Collapse << | Phase 3 | Unknown | March 2013 | Iran, Islamic Republic of ... more >> Imam Khomeini General Hospital Recruiting Tehran, Iran, Islamic Republic of Contact: Mohammad Jalili, MD 00982166904848 mjalili@tums.ac.ir Contact: Mohammadreza Hedayatshodeh, MD 00989125357410 mmd.hedy@yahoo.com Principal Investigator: Mohammadreza Hedayatshodeh, MD Shariati Hospital Recruiting Tehran, Iran, Islamic Republic of Contact: Mohammad Jalili, MD 00982166904848 mjalili@tums.ac.ir Principal Investigator: Mohammadreza Hedayatshodeh, MD Collapse << |
NCT00170781 | Acute Gouty Arthritis | Phase 4 | Completed | - | Germany ... more >> Novartis Nuernberg, Germany Switzerland For Site Information, contact Novartis Pharma AG Basel, CH, Switzerland, 4002 Collapse << |
NCT02183155 | Healthy | Phase 4 | Completed | - | - |
NCT00616382 | Patent Ductus Arteriosus | Phase 2 | Unknown | - | Israel ... more >> Neonatal Intensive Care Unit - Shaare Zedek Medical Center Not yet recruiting Jerusalem, Israel, 91031 Principal Investigator: Cathy Hammerman, MD Sub-Investigator: Irina Schorrs, MD Sub-Investigator: Amiram Nir, MD Collapse << |
NCT00855920 | Acute Gout Flare | Phase 3 | Completed | - | - |
NCT00210470 | Squamous Cell Carcinoma of the... more >> Head and Neck Collapse << | Phase 2 | Completed | - | United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, California Stanford Cancer Center Stanford, California, United States, 94305-5826 United States, Iowa University of Iowa Hospital & Clinics Iowa City, Iowa, United States, 52242 United States, Kentucky University of Kentucky Chandler Medical Center Lexington, Kentucky, United States, 40536 United States, Massachusetts Lahey Clinic Medical Center Burlington, Massachusetts, United States, 01805 United States, Michigan University of Michigan Hospitals Ann Arbor, Michigan, United States, 48109-0312 United States, New York Montefiore Medical Center Bronx, New York, United States, 10467 United States, Pennsylvania Hospital of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT00855920 | - | - | Completed | - | - |
NCT01733485 | Asthma Electr... more >>ophilic Fatty Acids Collapse << | Phase 1 | Completed | - | United States, Pennsylvania ... more >> University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
NCT00210470 | - | - | Completed | - | - |
NCT00997581 | Acute Gout | Phase 2 | Withdrawn(Colaborator withdrew... more >> support.) Collapse << | December 2010 | United States, New Hampshire ... more >> Dartmouth-Hitchcock Medical Center Lebanon, New Hampshire, United States, 03756 Collapse << |
NCT00500305 | Indomethacin Therapy ... more >> Patent Ductus Arteriosus Collapse << | Not Applicable | Completed | - | - |
NCT00116623 | Labor, Premature | Phase 4 | Terminated(Funding completed) | - | United States, Pennsylvania ... more >> University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT02653638 | Cerebrovascular Circulation | Early Phase 1 | Recruiting | June 2019 | United States, Wisconsin ... more >> Gymnasium-Natatorium Recruiting Madison, Wisconsin, United States, 53716 Contact: Anna Howery, MS 608-262-9572 barneslab@education.wisc.edu Collapse << |
NCT00554307 | - | - | Withdrawn(Not able to enroll p... more >>atients) Collapse << | - | United States, Kentucky ... more >> Kosair Children's Hospital Lousiville, Kentucky, United States, 40202 Collapse << |
NCT02964403 | Pancreatitis, Acute | Phase 4 | Unknown | August 2018 | - |
NCT00943345 | Gastrointestinal Diseases | Early Phase 1 | Unknown | February 2012 | Netherlands ... more >> Maastricht University Medical Center Maastricht, Zuid-Limburg, Netherlands Collapse << |
NCT02959112 | Pancreatitis, Acute | Not Applicable | Recruiting | - | Mexico ... more >> Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Recruiting Mexico City, Tlalpan, Mexico, 14000 Contact: Félix I Téllez-Ávila, M.D.,Ph.D. +525 554870900 ext 2150 felixtelleza@gmail.com Contact: Adriana F Romano-Munive, M.D.,M.Sc. +525 554870900 ext 2150 fab_romanom@hotmail.com Collapse << |
NCT03562624 | Contraception | Phase 2 | Recruiting | July 24, 2019 | Germany ... more >> Nuvisan GmbH Recruiting Neu-Ulm, Bayern, Germany, 89231 Frauenarztpraxis Dr. Wetzel Not yet recruiting Blankenburg, Sachsen-Anhalt, Germany, 38889 Dinox GmbH Berlin Recruiting Berlin, Germany, 10115 CRS Clinical Research Services Berlin GmbH Recruiting Berlin, Germany, 13353 CTC North GmbH & Co. KG Recruiting Hamburg, Germany, 20251 Praxis Hr. Dr. K. Peters Not yet recruiting Hamburg, Germany, 22159 United Kingdom PAREXEL International Early Phase Clinical Unit (London) Not yet recruiting Harrow, United Kingdom, HA1 3UJ Collapse << |
NCT02947932 | Pancreatitis, Acute ... more >> Gastrointestinal Disease Collapse << | Phase 4 | Unknown | September 2018 | - |
NCT02620761 | Patent Ductus Arteriosus (PDA)... more >> Acute Kidney Injury (AKI) Collapse << | Phase 2 Phase 3 | Not yet recruiting | December 2019 | - |
NCT00347035 | Glaucoma | Phase 4 | Terminated | - | - |
NCT00002796 | Mucinous Adenocarcinoma of the... more >> Colon Mucinous Adenocarcinoma of the Rectum Recurrent Colon Cancer Recurrent Rectal Cancer Signet Ring Adenocarcinoma of the Colon Signet Ring Adenocarcinoma of the Rectum Stage IVA Colon Cancer Stage IVA Rectal Cancer Stage IVB Colon Cancer Stage IVB Rectal Cancer Collapse << | Phase 1 Phase 2 | Terminated(Administratively co... more >>mplete.) Collapse << | - | United States, New York ... more >> Mount Sinai Medical Center New York, New York, United States, 10029 Collapse << |
NCT00142558 | Acute Gout | Phase 4 | Completed | - | - |
NCT01884272 | Gout | Phase 1 | Completed | - | United States, Michigan ... more >> Kalamazoo, Michigan, United States, 49007 Collapse << |
NCT01543685 | Other Acute Postoperative Pain | Phase 3 | Completed | - | United States, Arizona ... more >> Premier Research Group Limited Phoenix, Arizona, United States, 85027 United States, Maryland Chesapeake Research Group, LLC Pasadena, Maryland, United States, 21122 United States, Texas Premier Research Group Limited Austin, Texas, United States, 78705 United States, Utah Premier Research Group Limited Salt Lake City, Utah, United States, 84107 Collapse << |
NCT00239512 | Ductus Arteriosus, Patent ... more >> Preterm Infants Collapse << | Not Applicable | Terminated | - | Taiwan ... more >> China Medical University Hospital Taichung, Taiwan, 404-08 Collapse << |
NCT02849990 | Stage III Prostate Adenocarcin... more >>oma AJCC v7 Stage III Prostate Cancer AJCC v7 Stage IV Prostate Adenocarcinoma AJCC v7 Stage IV Prostate Cancer AJCC v7 Collapse << | Phase 2 | Recruiting | July 15, 2020 | United States, Washington ... more >> Fred Hutch/University of Washington Cancer Consortium Recruiting Seattle, Washington, United States, 98109 Contact: Michael Schweizer 206-606-6252 schweize@uw.edu Principal Investigator: Michael Schweizer Collapse << |
NCT00904904 | Cataract Infl... more >>ammation Collapse << | Phase 4 | Completed | - | Germany ... more >> Bausch & Lomb Berlin, Germany, D 13581 Collapse << |
NCT01543685 | - | - | Completed | - | - |
NCT03620825 | Dehydration I... more >>ndomethacin Collapse << | Not Applicable | Completed | - | Sweden ... more >> Örebro University Örebro, Örebro County, Sweden, 70182 Collapse << |
NCT00470743 | Ductus Arteriosus, Patent ... more >> Very Low Birth Weight Infants Collapse << | Phase 4 | Withdrawn(Funding withdrawn) | June 2009 | Singapore ... more >> KK Women's and Children's Hospital / National University Hospital Singapore, Singapore, 229899 Collapse << |
NCT00275730 | Ocular Physiology ... more >> Regional Blood Flow Collapse << | Not Applicable | Completed | - | Austria ... more >> Department of Clinical Pharmacology Vienna, Austria, 1090 Collapse << |
NCT02183168 | Spondylitis, Ankylosing | Phase 3 | Completed | - | - |
NCT00964431 | - | - | Completed | - | - |
NCT02451228 | - | - | Recruiting | May 2019 | United States, Alabama ... more >> University of Alabama Recruiting Birmingham, Alabama, United States, 35233 Contact: Lisa Dimperio 205-934-3276 ldimperio@uabmc.edu Contact: Nancy Saxon, RN nbsaxon@uabmc.edu Sub-Investigator: Alan Tita, MD Principal Investigator: Amelia Sutton, MD United States, Mississippi University of Mississippi Medical Center Recruiting Jackson, Mississippi, United States, 39216 Contact: Tony Wen, MD twen@umc.edu Contact: Latasha Cox, MHSA 601-815-5018 lcox2@umc.edu Principal Investigator: Tony Wen, MD United States, New York Columbia University Recruiting New York, New York, United States, 10032 Contact: Caroline Torres 212-305-2158 ct2179@cumc.columbia.edu Principal Investigator: Kirsten Cleary, MD United States, North Carolina Duke University Recruiting Durham, North Carolina, United States, 27705 Contact: Kristin Weaver 919-681-0308 kristin.weaver@duke.edu Principal Investigator: Chad Grotegut, MD United States, Texas University of Texas Medical Branch, Dept of OB/GYN Recruiting Galveston, Texas, United States, 77555-0587 Contact: Holly West, DHEd, PA-C 409-747-8234 hawest@utmb.edu Contact: Ashley Salazar, WHNP 409-772-0312 assala@utmb.edu Principal Investigator: Gary Hankins, MD Principal Investigator: Erik Rytting, PhD Sub-Investigator: Maged Costantine, MD Sub-Investigator: Shannon Clark, MD Sub-Investigator: Tatiana Nanovskaya, DDS, PhD Sub-Investigator: Michael Cohen-Wolkowiez, MD, PhD United States, Utah University of Utah Recruiting Salt Lake City, Utah, United States, 84132 Contact: Marie Gibson 801-213-2845 Marie.Gibson@hsc.utah.edu Principal Investigator: Erin Clark, MD Collapse << |
NCT00722033 | Regional Blood Flow ... more >> Premature Birth Electroencephalography Collapse << | Phase 2 | Unknown | December 2009 | Chile ... more >> Puc, Nicu Recruiting Santiago, Area Metropolitana, Chile, 833-0024 Contact: Paulina M Toso, MD 56-2-3546437 ptoso@med.puc.cl Principal Investigator: Paulina M Toso, MD Collapse << |
NCT00187447 | Patent Ductus Arteriosus | Phase 2 | Completed | - | United States, California ... more >> University of California San Francisco Davis, California, United States, 94143 United States, Illinois University of Chicago Chicago, Illinois, United States United States, Rhode Island Brown University Providence, Rhode Island, United States Collapse << |
NCT00432081 | Alzheimer Disease | Phase 3 | Completed | - | Netherlands ... more >> Rijnstate Hospital Arnhem, Netherlands, 6800 TA Radboud University Medical Center Nijmegen, Netherlands, 6500 HB Collapse << |
NCT00820612 | Post-ERCP Pancreatitis | Phase 4 | Terminated(Stopped by DSMB for... more >> overwhelming benefit of indomethacin (unethical to withhold indomethacin from patients)) Collapse << | - | United States, Indiana ... more >> Indiana University Medical Center Indianapolis, Indiana, United States, 46202 United States, Kentucky University of Kentucky Lexington, Kentucky, United States, 40536 United States, Michigan University of Michigan Ann Arbor, Michigan, United States, 48109 United States, Ohio University Hospitals Case Medical Center Cleveland, Ohio, United States, 44106 Collapse << |
NCT00485160 | Patent Ductus Arteriosus | Phase 3 | Completed | - | Israel ... more >> Shaare Zedek Medical Center Jerusalem, Israel Collapse << |
NCT00964431 | Dental Pain | Phase 2 | Completed | - | United States, Texas ... more >> Premier Research Group Limited Austin, Texas, United States, 78705 Collapse << |
NCT00820612 | - | - | Terminated(Stopped by DSMB for... more >> overwhelming benefit of indomethacin (unethical to withhold indomethacin from patients)) Collapse << | - | - |
NCT00033917 | - | - | Completed | - | - |
NCT00033917 | Intraventricular Hemorrhage (I... more >>VH) Bleeding in the Brain Prematurity Very Low Birth Weight Infants Collapse << | Phase 3 | Completed | - | United States, Connecticut ... more >> Yale University School of Medicine New Haven, Connecticut, United States United States, Maine Maine Medical Center Portland, Maine, United States United States, Rhode Island Brown University School of Medicine Providence, Rhode Island, United States Collapse << |
NCT01146197 | Gitelman Syndrome | Phase 1 Phase 2 | Completed | - | France ... more >> Hopital Européen Georges Pompidou Paris, France, 75015 Collapse << |
NCT01626118 | - | - | Completed | - | - |
NCT01758913 | Patent Ductus Arteriosus | Not Applicable | Completed | - | United States, Illinois ... more >> John H. Stroger, Jr. Hospital of Cook County Chicago, Illinois, United States, 60612 Collapse << |
NCT03582332 | Axial Spondyloarthritis | Phase 4 | Completed | - | - |
NCT00462111 | Healthy | Phase 4 | Completed | - | Netherlands ... more >> Sint Maartenskliniek Nijmegen, Netherlands, 6522 JV Collapse << |
NCT00009646 | Infant, Very Low Birth Weight ... more >> Infant, Premature Ductus Arteriosus, Patent Collapse << | Phase 3 | Completed | - | United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35233 United States, California Stanford University Palo Alto, California, United States, 94304 United States, Florida University of Miami Miami, Florida, United States, 33136 United States, Georgia Emory University Atlanta, Georgia, United States, 30303 United States, Michigan Wayne State University Detroit, Michigan, United States, 48201 United States, New Mexico University of New Mexico Albuquerque, New Mexico, United States, 87131 United States, Ohio Case Western Reserve University, Rainbow Babies and Children's Hospital Cleveland, Ohio, United States, 44106 United States, Rhode Island Brown University, Women & Infants Hospital of Rhode Island Providence, Rhode Island, United States, 02905 United States, Texas University of Texas Southwestern Medical Center at Dallas Dallas, Texas, United States, 75235 Collapse << |
NCT02641561 | - | - | Completed | - | - |
NCT00858195 | Inflammation | Phase 1 | Completed | - | - |
NCT01626118 | Other Acute Postoperative Pain | Phase 3 | Completed | - | United States, Arizona ... more >> Premier Research Group Limited Phoenix, Arizona, United States, 85027 United States, Maryland Chesapeake Research Group, LLC Pasadena, Maryland, United States, 21122 United States, Texas Premier Research Group Limited Austin, Texas, United States, 78705 United States, Utah Premier Research Group Limited Salt Lake City, Utah, United States, 84107 Collapse << |
NCT03712241 | Healthy | Phase 1 | Not yet recruiting | November 2018 | United States, Texas ... more >> PPD Development, LP Not yet recruiting Austin, Texas, United States, 78744 Collapse << |
NCT02641561 | Post-ERCP Acute Pancreatitis | Phase 3 | Completed | - | United States, New Jersey ... more >> Cooper Hospital Camden, New Jersey, United States, 08103 Collapse << |
NCT02797067 | Pancreatitis | Phase 4 | Unknown | June 2018 | China ... more >> Shanghai Changhai Hospital Recruiting Shanghai, China Contact: Zhao-shen Li zhaoshen-li@hotmail.com Contact: Zhuan Liao liaozhuan@smmu.edu.cn Sub-Investigator: Liang-hao Hu Sub-Investigator: Yang-yang Qian Collapse << |
NCT01722110 | Fed | Phase 1 | Completed | - | India ... more >> Accutest Research Lab (I) Pvt. Ltd. Navi-Mumbai, Maharashtra, India, 400 709 Collapse << |
NCT00466128 | Preterm Premature Rupture of M... more >>embranes Collapse << | Phase 2 | Unknown | April 2016 | United States, Pennsylvania ... more >> Thomas Jefferson University Hospital Recruiting Philadelphia, Pennsylvania, United States, 19107 Contact: Jolene S Seibel-Seamon, MD 215-955-6293 joleneseibel@yahoo.com Principal Investigator: Jolene S Seibel-Seamon, MD Collapse << |
NCT00226122 | Enuresis | Phase 4 | Completed | - | Denmark ... more >> Dept of Pediatrics, Aarhus University Hospital Aarhus N, Jutland, Denmark, 8200 Collapse << |
NCT01114516 | Cervical Insufficiency | Not Applicable | Completed | - | United States, Illinois ... more >> Prentice Women's Hospital Chicago, Illinois, United States, 60611 Collapse << |
NCT00486824 | Obstetric Labor, Premature | Phase 1 Phase 2 | Completed | - | United States, California ... more >> Stanford University School of Medicine Stanford, California, United States, 94305 Collapse << |
NCT01719926 | Colorectal Neoplasms ... more >> Esophageal Neoplasms Ovarian Neoplasms Collapse << | Phase 1 | Completed | - | Netherlands ... more >> Meander Medisch Centrum Amersfoort, Utrecht, Netherlands, 3813TZ the Netherlands Cancer Institute Amsterdam, Netherlands, 1066 CX UMC Utrecht Utrecht, Netherlands, 3584CX Switzerland Oncology Institute of Southern Switzerland Bellinzona, Switzerland, CH-6500 Collapse << |
NCT00486824 | - | - | Completed | - | - |
NCT00727740 | - | - | Completed | - | - |
NCT00727740 | Pancreatitis | Not Applicable | Completed | - | United States, Connecticut ... more >> Yale New Haven Hospital New Haven, Connecticut, United States, 06520 Collapse << |
NCT01070745 | Patent Ductus Arteriosus | Phase 2 | Withdrawn(Changes in approach ... more >>to PDA therapy) Collapse << | - | Israel ... more >> Shaare Zedek Medical Center Jerusalem, Israel, 91031 Collapse << |
NCT01577121 | Preterm Labor With Intact Memb... more >>ranes Collapse << | Phase 2 | Completed | - | Spain ... more >> Hospital Clinic of Barcelona- Maternity Barcelona, Spain, 08028 Collapse << |
NCT02709421 | - | - | Completed | - | China, Fujian ... more >> Department of gastroenterology,Chinese PLA 174 Hospital Xiamen, Fujian, China China, Shaanxi The First Affiliated Hospital of Xi'an Jiaotong University Xi'an, Shaanxi, China Xijing Hospital of Digestive Diseases Xi'an, Shaanxi, China Collapse << |
NCT01744314 | Elbow Trauma Requiring Operati... more >>ve Management Collapse << | Not Applicable | Recruiting | November 2019 | Canada, Ontario ... more >> HULC, St Joseph's Health Care Recruiting London, Ontario, Canada, N6A 4V2 Contact: George Athwal, MD 519-646-6100 gathwal@uwo.ca Collapse << |
NCT03057769 | Pancreatitis ... more >>Endoscopic Retrograde Cholangiopancreatography Collapse << | Not Applicable | Terminated(This study was term... more >>inated because of an interim analysis suggesting futility of papillary epinephrine spraying in PEP prevention.) Collapse << | - | China, Fujian ... more >> Department of Gastroenterology, Successful Hospital of Xiamen university Xiamen, Fujian, China, 361000 Department of Gastroenterology, Zhongshan Hospital of Xiamen university Xiamen, Fujian, China, 361004 China, Gansu Department of General Surgery, The First Hospital of Lanzhou University Lanzhou, Gansu, China, 730000 China, Shaanxi Endoscopy Center, Ankang Central Hospital Ankang, Shaanxi, China, 725000 Xijing Hospital of Digestive Diseases Xi'an, Shaanxi, China, 710032 Department of Gastroenterology, No. 451 Hospital Xi'an, Shaanxi, China, 710068 China, Xinjiang Department of Gastroenterology, The First Affiliated Hospital of the Medical College, Shihezi University Shihezi, Xinjiang, China, 832008 Department of Gastroenterology, Urumqi General Hospital of Lanzhou Military Region Urumqi, Xinjiang, China, 830000 China, Zhejiang Department of Gastroenterology, Hangzhou First People's Hospital Hangzhou, Zhejiang, China, 310006 China Department of Hepatobiliary Surgery, General Hospital of Ningxia Medical University Yinchuan, China, 750004 Collapse << |
NCT01912716 | Post-ERCP Pancreatitis | Phase 2 Phase 3 | Completed | - | United States, Indiana ... more >> Indiana University Health Indianapolis, Indiana, United States, 46202 United States, Massachusetts Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02215 United States, Michigan University of Michigan Medical Center Ann Arbor, Michigan, United States United States, South Carolina Medical University of South Carolina Charleston, South Carolina, United States, 29425 United States, Texas Methodist Dallas Medical Center Dallas, Texas, United States United States, Wisconsin Aurora St. Lukes' Medical Center Milwaukee, Wisconsin, United States Collapse << |
NCT02116309 | Post-ERCP Acute Pancreatitis | Not Applicable | Completed | - | United States, Maryland ... more >> Johns Hopkins Medical Institutions Baltimore, Maryland, United States, 21287 India Asian Institute of gastroenterology Hyderabad, Andhra Pradesh, India, 500082 Apollo Gleneagles Hospitals Kolkata, West Bengal, India, 700054 Post Graduate Institute of Medical Education and Research Chandigarh, India, 160012 Collapse << |
NCT00750581 | Patent Ductus Arteriosus | Phase 2 Phase 3 | Terminated(Study medication wa... more >>s no longer available for study) Collapse << | - | Canada, Alberta ... more >> Foothills Medical Centre Calgary, Alberta, Canada, T2N 2T9 Collapse << |
NCT00728117 | Patent Ductus Arteriosus | Not Applicable | Completed | - | United States, California ... more >> University of California san Francisco San Francisco, California, United States, 94143 Santa Clara Valley Medical Center San Jose, California, United States, 95128 United States, Illinois Children's Memorial Hospital-Northwestern University Chicago, Illinois, United States, 60614 North Shore University Health System, Northwestern University Evanston, Illinois, United States, 60201 United States, Massachusetts Boston University-Boston Medical Center Boston, Massachusetts, United States, 02118 United States, Minnesota Children's Hospital-Minneapolis Minneapolis, Minnesota, United States, 55404 Mayo Clinic Rochester, Minnesota, United States, 85359 Children's Hospital-Saint Paul Saint Paul, Minnesota, United States, 55102 United States, New Jersey Atlantic Health Organization Morristown, New Jersey, United States, 07962 United States, New York Columbia University New York, New York, United States, 10032 United States, Ohio Case Western Reserve Cleveland, Ohio, United States, 44106 United States, Pennsylvania University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15122 United States, Tennessee Vanderbilt University Nashville, Tennessee, United States, 37232 United States, Virginia University of Virginia, Charlottesville Charlottesville, Virginia, United States, 22908 Collapse << |
NCT01073670 | Hemorrhage | Phase 4 | Completed | - | Canada, Ontario ... more >> Kingston General Hospital Kingston, Ontario, Canada, K7L 2V7 Collapse << |
NCT01957215 | Ankle Sprain | Phase 4 | Completed | - | China, Jiangsu ... more >> Changzhou NO.2 People's Hospital Changzhou, Jiangsu, China, 213003 Changzhou NO.2 People?s Hospital Changzhou, Jiangsu, China, 213003 Zhongda Hospital Southeast University Nanjing, Jiangsu, China, 210009 The First Affiliated Hospital of Soochow University Suzhou, Jiangsu, China, 215006 China, Shanghai Ruijin Hospital Luwan Branch Shanghai, Shanghai, China, 200020 Shanghai Ruijin Hospital Shanghai, Shanghai, China, 200025 Shanghai Xuhui Centre Hospital Shanghai, Shanghai, China, 200031 Shanghai Tenth People's Hospital Shanghai, Shanghai, China, 200072 Shanghai Tenth People?s Hospital Shanghai, Shanghai, China, 200072 Shanghai Tenth Peoples Hospital Shanghai, Shanghai, China, 200072 Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine Shanghai, Shanghai, China, 200092 Shanghai East Hospital Shanghai, Shanghai, China, 200120 Shanghai First People's Hospital Shanghai, Shanghai, China, 201620 Shanghai First People?s Hospital Shanghai, Shanghai, China, 201620 Shanghai First Peoples Hospital Shanghai, Shanghai, China, 201620 Collapse << |
NCT01957215 | - | - | Completed | - | - |
NCT02476279 | Post-ERCP Pancreatitis | Phase 3 | Recruiting | June 2021 | United States, Colorado ... more >> University of Colorado Recruiting Denver, Colorado, United States Contact: Sachin Wani United States, Florida The Florida Hospital Recruiting Orlando, Florida, United States Contact: Shyam Varadarajulu United States, Georgia Emory University Recruiting Atlanta, Georgia, United States Contact: Field Willingham United States, Maryland Johns Hopkins University Recruiting Baltimore, Maryland, United States Contact: Vikesh Singh United States, Michigan University of Michigan Recruiting Ann Arbor, Michigan, United States Contact: James Schieman United States, Missouri Washington University Recruiting Saint Louis, Missouri, United States Contact: Steve Edmundowicz United States, Ohio Case Western Reserve University Recruiting Cleveland, Ohio, United States Contact: Amitabh Chak United States, Pennsylvania University of Pittsburgh Recruiting Pittsburgh, Pennsylvania, United States Contact: Georgios Papachristou United States, South Carolina Medical University of South Carolina Recruiting Charleston, South Carolina, United States Contact: Joe Elmunzer Collapse << |
NCT03261635 | Macular Edema | Phase 4 | Completed | - | - |
NCT02438371 | Preterm Labor | Phase 4 | Recruiting | March 2020 | United States, Texas ... more >> Memorial Hermann Hospital Texas Medical Center Recruiting Houston, Texas, United States, 77030 Contact: Jerrie S Refuerzo, M.D. 713-500-6416 Jerrie.S.Refuerzo@uth.tmc.edu Contact: Maria Hutchinson, M.S 713-500-5850 Maria.S.Keefer@uth.tmc.edu Principal Investigator: Jerrie S Refuerzo, M.D. Collapse << |
NCT02711358 | Family Planning | Phase 4 | Completed | - | Egypt ... more >> Ahmed Abbas Assiut, Cairo, Egypt, 002 Collapse << |
NCT01774604 | Post-ERCP Acute Pancreatitis | Phase 3 | Terminated(Futility) | - | United States, New Hampshire ... more >> Dartmouth-Hitchcock Medical Center Lebanon, New Hampshire, United States, 03756 Collapse << |
NCT01114516 | - | - | Completed | - | - |
NCT01774604 | - | - | Terminated(Futility) | - | - |
NCT01869361 | Preterm Labor | Early Phase 1 | Not yet recruiting | December 2021 | United States, Ohio ... more >> MetroHealth Medical Center Not yet recruiting Cleveland, Ohio, United States, 44109 Principal Investigator: Kelly S Gibson, MD Collapse << |
NCT02935205 | Metastatic Prostate Carcinoma ... more >> Recurrent Prostate Carcinoma Stage IV Prostate Cancer Collapse << | Phase 1 Phase 2 | Recruiting | December 2020 | United States, California ... more >> University of California Davis Comprehensive Cancer Center Recruiting Sacramento, California, United States, 95817 Contact: Chong-Xian Pan 916-734-3771 cxpan@ucdavis.edu Principal Investigator: Chong-Xian Pan Collapse << |
NCT02221219 | Intraventricular Hemorrhage ... more >> Periventricular Leukomalacia Brain Injury Renal Injury Collapse << | Phase 1 Phase 2 | Recruiting | December 2020 | United States, Kentucky ... more >> Kentucky Childrens Hospital Neonatal Intensive Care Unit Recruiting Lexington, Kentucky, United States, 40506 Collapse << |
NCT03547232 | Acute Pancreatitis ... more >> Complication Collapse << | Phase 3 | Recruiting | July 30, 2020 | China, Beijing ... more >> Peking Union Medical College Hospital Recruiting Beijing, Beijing, China, 100730 Contact: Dong Wu, M.D. Collapse << |
NCT01360034 | Obstetric Labor, Premature | Phase 3 | Unknown | June 2016 | Panama ... more >> Saint Thomas Hospital Panama, Panama Collapse << |
NCT02111707 | Acute Pancreatitis | Phase 4 | Completed | - | Canada, Alberta ... more >> University of Alberta Edmonton, Alberta, Canada, T6G2X8 Collapse << |
NCT02692391 | Acute Pancreatitis | Phase 3 | Recruiting | June 2021 | United States, Pennsylvania ... more >> Univeristy of Pittsburgh Recruiting Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
NCT03129945 | Obstetric Labor, Premature | Not Applicable | Active, not recruiting | September 2019 | United States, California ... more >> University of California, Los Angeles Los Angeles, California, United States, 90095 University of California, Irvine Orange, California, United States, 92868 University of California, Davis Sacramento, California, United States, 95817 University of California, San Diego San Diego, California, United States, 92103 University of California, San Francisco San Francisco, California, United States, 94143 Collapse << |
NCT03662269 | Refractory Chronic Cough | Phase 3 | Recruiting | December 30, 2020 | China, Guangdong ... more >> The First Affiliated Hospital Of Guangzhou Medical University Recruiting Guangzhou, Guangdong, China, 520120 Contact: Kefang Lai, PHD 83062893 ext 020 klai@163.com Principal Investigator: Kefang Lai, PHD Collapse << |
NCT02116309 | - | - | Completed | - | - |
NCT03533803 | Difficult Embryo Transfer | Phase 3 | Completed | - | Egypt ... more >> Nile IVF center Giza, Egypt, 12411 Collapse << |
NCT02110810 | Post ERCP Acute Pancreatitis | Phase 3 | Completed | - | Mexico ... more >> Department of Gastrointestinal Endoscopy and Department of Gastroenterology of the Specialties Hospital of the Western Medical Center of the Mexican Institute of Social Security. Guadalajara, Jalisco, Mexico Collapse << |
NCT02002650 | Post-ERCP Acute Pancreatitis | Not Applicable | Completed | - | China, Gansu ... more >> The First Hospital of Lanzhou University Lanzhou, Gansu, China, 730000 China, Ningxia General Hospital of NingXia Medical University Yinchuan, Ningxia, China, 750004 China, Shaanxi Xijing Hospital of Digestive Diseases Xi'an, Shaanxi, China, 710032 No. 451 Hospital Xi'an, Shaanxi, China, 710054 The First Affiliated Hospital Of Xi'an Jiaotong University Xi'an, Shaanxi, China, 710061 China, Xinjiang Urumqi General Hospital of Lanzhou Military Region Urumqi, Xinjiang, China, 830002 Collapse << |
NCT02002650 | - | - | Completed | - | - |
NCT03643900 | Post-ERCP Pancreatitis ... more >> Pancreatitis, Acute Necrotizing Collapse << | Not Applicable | Recruiting | December 31, 2019 | China, Zhejiang ... more >> Hangzhou First People's Hospital Recruiting Hangzhou, Zhejiang, China, 31006 Contact: Jianfeng Yang, M.D +86-0571-56006999 yjf-1976@163.com Contact: Yahong He, M.S +86-15869127175 hyhdoctor19@126.com Collapse << |
NCT03713879 | Post ERCP Pancreatitis | Phase 3 | Not yet recruiting | December 31, 2023 | Hong Kong ... more >> Endoscopy Centre, Prince of Wales Hospital Hong Kong, Hong Kong Collapse << |
NCT02642601 | Difficult Embryo Transfer | Phase 2 Phase 3 | Unknown | January 2016 | Egypt ... more >> IVF center,Cairo university hospital,Egypt Recruiting Cairo, Egypt Contact: Sherin H Gad Allah, MD +201097665573 sherinehosny@gmail.com Contact: Mona M Shaban, MD +201001078586 drmonashaban@gmail.com Kamal Shoeir private IVF center,Cairo,Egypt Recruiting Cairo, Egypt Contact: Mona M Shaban, MD +201001078586 drmonashaban@gmail.com Contact: Sherine H Gad Allah, MD +201097665573 sherinehosny@gmail.com Collapse << |
NCT03629600 | Post-ERCP Acute Pancreatitis | Phase 2 Phase 3 | Completed | - | India ... more >> IPGIMER Kolkata, West Bengal, India, 700020 Collapse << |
NCT03537144 | Patent Ductus Arteriosus | Phase 3 | Recruiting | June 2019 | United States, Tennessee ... more >> LeBonheur Children's Hospital Recruiting Memphis, Tennessee, United States, 38103 Contact: Jennifer M Hendrick, DO 901-448-8456 jhendr20@uthsc.edu Principal Investigator: John M Ferguson, MD Sub-Investigator: Jennifer M Hendrick, DO Methodist-Lebonheur Germantown Hospital Recruiting Memphis, Tennessee, United States, 38138 Contact: Elizabeth L Ivey, NNP-BC 901-516-6433 eivey@uthsc.edu Sub-Investigator: Martin B Jenkins, MD Regional One Health Recruiting Memphis, Tennessee, United States, 38163 Contact: Jennifer M Hendrick, MD 901-448-8459 jhendr20@uthsc.edu Principal Investigator: John M Ferguson, MD Sub-Investigator: Jennifer M Hendrick, DO Collapse << |
NCT02633969 | Pain, Postoperative | Phase 2 | Completed | - | United States, Alabama ... more >> Sheffield, Alabama, United States, 35660 United States, Colorado Aurora, Colorado, United States, 80045 United States, Florida Coral Gables, Florida, United States, 33146 United States, North Carolina Durham, North Carolina, United States, 27705 United States, Utah Orem, Utah, United States, 84058 Collapse << |
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