CAS No.: 1000403-03-1
INT-767 Catalog No. CSN17377
INT-767 is a potent agonist for both FXR (mean EC50, 30 nM by PerkinElmer AlphaScreen assay) and TGR5 (mean EC50, 630 nM by time resolved-fluorescence resonance energy transfer).
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
|---|
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Baghdasaryan A, Claudel T,et al. Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output. Hepatology. 2011 Oct;54(4):1303-12.
- [2] Rizzo G, Passeri D, et al. Functional characterization of the semisynthetic bile acid derivative INT-767, a dual farnesoid X receptor and TGR5 agonist. Mol Pharmacol. 2010 Oct;78(4):617-30.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1000403-03-1 | 储存条件 |
|
|
| 分子式 | C25H43NaO6S | 运输 | 蓝冰 | |
| 分子量 | 494.66 | 别名 |
