|N1,N3-双(2,3-二羟丙基)-2,4,6-三碘-5-(2-甲氧基乙酰胺)-N1-甲基间苯二甲酰胺|CsnPharm

CAS No.: 73334-07-3

Iopromide/碘普罗胺 Catalog No. CSN22575

Synonyms: Ultravist;Iopromidum;SHL 414C

Iopromide is a non-ionic, water-soluble X-ray contrast agent for intravascular administration.

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技术信息

生物活性

描述No toxic effects are detected at the highest tested concentration of Iopromide (10 g/L) in short-term toxicity tests with bacteria (Vibrio fisheri, Pseudomonas putida), algae (Scenedesmus subspicatus), crustaceans (Daphnia magna), and fish (Danio rerio, Leuciscus idus). Iopromide results in the ratio between the predicted environmental concentration (PEC) and the predicted no-effect concentration (PNEC) of 2 × 10 using an assessment factor of 100. Iopromide results in the photocatalytic degradation values k of 0.18 and the coefficient of determination R of 0.997 in Milli-Q water with suspended TiO. The percent removal of Iopromide decreases from 97% to 86% when the activity of the nitrifying bacteria is inhibited. Iopromide results in metabolite of carboxylate formed during the oxidation of the primary alcohol on the side chain of iopromide when the nitrifying bacteria are inhibited. Iopromide (0.1 mg/L to 0.27 mg/L) is removed more effectively in the nitrifying activate sludge which has a higher SRT (49 days) than in the conventional activated sludge (SRT of 6 days). Iopromide (0.1 mg/L to 0.27 mg/L) is removed more effectively in the nitrifying activate sludge which has a higher SRT (49 days) than in the conventional activated sludge (SRT of 6 days). The percent removal of Iopromide in the wastewater treatment plants reaches 61% in nitrifying activated sludge. Iopromide-dosed plant at 0.1 mg/L, 1 mg/L and 100 mg/L results in the median of DOC-degradation of the synthetic sewage of 88.5%, 90.5%, 88.4% and 85.1%, respectively. Iopromide is eliminated to more than 80% in the 100 mg/L concentration after a lag period of 31 days. In the LSTP incubated with 1 mg/L Iopromide elimination reaches more than 80% after 38 days. Iopromide results in half-life of photodegradation of free amine of 4.21 hours.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.2640 mL
- 6.3202 mL
- 12.6405 mL
- 5 mM
- 0.2528 mL
- 1.2640 mL
- 2.5281 mL
- 10 mM
- 0.1264 mL
- 0.6320 mL
- 1.2640 mL

技术信息

CAS号

73334-07-3

储存条件

粉末: Keep in dark place,Inert atmosphere,Room temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C18H24I3N3O8

运输

蓝冰

分子量

791.11

别名

Ultravist;Iopromidum;SHL 414C;Ultravist (pharmacy bulk);Ultravist 150;Ultravist 240;Ultravist 300;Ultravist 370;UNII-712BAC33MZ;ZK 35760;碘普罗胺

溶解度

DMSO	105.0 mg/mL (132.7 mM)
Water	100.0 mg/mL (126.4 mM)

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