CAS No.: 93859-63-3
Isochamaejasmin/异狼毒素 Catalog No. CSN14611
Synonyms: Isochamaejasmin;异狼毒素
Isochamaejasmine, a natural product isolated and purified from the roots of Stellera chamaejasme Linn., has inhibition of NF-kappaB activation reversed the anti-apoptotic effect, shows antiplasmodial activity, with an IC(50) of 7.3+/-3.8 mM, but the selectivity was rather limited, and induces apoptosis in leukemia cells by inhibiting the activity of Bcl-2 family proteins, providing evidence for further studying the underlying anti-cancer mechanism of S.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Dhooghe L, Maregesi S, et al. Antiplasmodial activity of (I-3,II-3)-biflavonoids and other constituents from Ormocarpum kirkii. Phytochemistry. 2010 May;71(7):785-91.
- [2] Tian Q, Li J, et al. Stereospecific induction of nuclear factor-kappaB activation by isochamaejasmin. Mol Pharmacol. 2005 Dec;68(6):1534-42. Epub 2005 Sep 1.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 93859-63-3 | 储存条件 |
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| 分子式 | C30H22O10 | 运输 | 蓝冰 | |
| 分子量 | 542.49 | 别名 | Isochamaejasmin;异狼毒素 |
