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CAS No.: 122898-67-3

Itopride Catalog No. CSN11238

Synonyms: HSR803 free base;HSR-803;N-((4-(2-(Dimethylamino)ethoxy)phenyl)methyl)-3,4-dimethoxybenzamide monohydrochloride

Itopride is a prokinetic benzamide derivative unlike metoclopramide or domperidone, and is indicated for the treatment of functional dyspepsia and other gastrointestinal conditions.

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生物活性

实验方案

技术信息

生物活性

描述Itopride is a prokinetic benzamide derivative unlike metoclopramide or domperidone, and is indicated for the treatment of functional dyspepsia and other gastrointestinal conditions.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01669772	Healthy Volunteers	Phase 1 Phase 2	Completed	-	Korea, Republic of ... more >> Seoul St Mary's hospital Seoul, Korea, Republic of Collapse <<
NCT01513096	Colonoscopy B... more >>owel Preparation Collapse <<	Phase 3	Completed	-	Korea, Republic of ... more >> Haeundae Paik Hospital, Inje University School of Medicine Busan, Korea, Republic of, 612-030 Collapse <<
NCT00308399	Healthy Volunteers	Phase 2 Phase 3	Completed	-	United States, Minnesota ... more >> Mayo Clinic Rochester, Minnesota, United States, 55905 Collapse <<

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参考文献

[1] Choi MG, Rhee PL, et al. Randomized, Controlled, Multi-center Trial: Comparing the Safety and Efficacy of DA-9701 and Itopride Hydrochloride in Patients With Functional Dyspepsia. J Neurogastroenterol Motil. 2015 Jul 30;21(3):414-22.
[2] Huang X, Lv B, et al. Itopride therapy for functional dyspepsia: a meta-analysis. World J Gastroenterol. 2012 Dec 28;18(48):7371-7.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.7899 mL
- 13.9497 mL
- 27.8995 mL
- 5 mM
- 0.5580 mL
- 2.7899 mL
- 5.5799 mL
- 10 mM
- 0.2790 mL
- 1.3950 mL
- 2.7899 mL

技术信息

CAS号	122898-67-3	储存条件	粉末 Sealed in dry,2-8°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C20H26N2O4	运输	蓝冰
分子量	358.43	别名	HSR803 free base;HSR-803;N-((4-(2-(Dimethylamino)ethoxy)phenyl)methyl)-3,4-dimethoxybenzamide monohydrochloride

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT01669772	Healthy Volunteers	Phase 1 Phase 2	Completed	-	Korea, Republic of ... more >> Seoul St Mary's hospital Seoul, Korea, Republic of Collapse <<
NCT01513096	Colonoscopy B... more >>owel Preparation Collapse <<	Phase 3	Completed	-	Korea, Republic of ... more >> Haeundae Paik Hospital, Inje University School of Medicine Busan, Korea, Republic of, 612-030 Collapse <<
NCT00308399	Healthy Volunteers	Phase 2 Phase 3	Completed	-	United States, Minnesota ... more >> Mayo Clinic Rochester, Minnesota, United States, 55905 Collapse <<
NCT01332890	Healthy	Phase 1	Completed	-	Korea, Republic of ... more >> ASAN Medical Center, University of Ulsan Seoul, Korea, Republic of Collapse <<
NCT00599677	Functional Dyspepsia	Not Applicable	Completed	-	China, Sichuan ... more >> Chengdu University of TCM Chengdu, Sichuan, China, 610075 Collapse <<
NCT00382577	Heartburn	Phase 3	Completed	-	United States, Oklahoma ... more >> The Oklahoma Foundation for Digestive Research Oklahoma City, Oklahoma, United States, 73104 Collapse <<
NCT00112190	Dyspepsia	Phase 3	Completed	-	Canada, Quebec ... more >> AXCAN Pharma Inc. Mont St-Hilaire, Quebec, Canada, J3H 6C4 Collapse <<
NCT00112203	Dyspepsia	Phase 3	Completed	-	-
NCT00112177	Dyspepsia	Phase 3	Completed	-	Canada, Quebec ... more >> Monique Giguère, Ph.D. - Programs Director Mont-Saint-Hilaire, Quebec, Canada, J3H 6C4 Collapse <<
NCT01027260	Irritable Bowel Syndrome	Phase 2	Completed	-	Pakistan ... more >> Site Reference ID/Investigator# 5870 Karachi, Pakistan, 74800 Site Reference ID/Investigator# 21441 Karachi, Pakistan Site Reference ID/Investigator# 6130 Lahore, Pakistan Site Reference ID/Investigator# 8535 Rawalpindi, Pakistan Collapse <<
NCT00370084	Gastroparesis	Phase 1 Phase 2	Completed	-	Australia, South Australia ... more >> University of Adelaide, Department of Medicine Adelaide, South Australia, Australia, 5000 Collapse <<
NCT00272103	Functional Dyspepsia	Phase 2 Phase 3	Completed	-	Germany ... more >> University Hospital Essen Essen, Germany, 45122 Collapse <<
NCT01513811	Constipation	Phase 2	Completed	-	China, Shanghai ... more >> Shanghai Jiao-Tong University School of Medicine Renji Hospital Shanghai, Shanghai, China, 200001 Collapse <<
NCT01226134	Functional Dyspepsia ... more >> Gastric Emptying Gastric Accommodation Collapse <<	Not Applicable	Unknown	May 2011	Pakistan ... more >> Aga Khan University Recruiting Karachi, Sindh, Pakistan, 74800 Principal Investigator: Shahab Abid, MD Sub-Investigator: Wasim Jafri, MD Sub-Investigator: Maseeh Uzzaman, MD Sub-Investigator: Rakhshanda Bilal Sub-Investigator: Soobia Siddiqui, MD Sub-Investigator: Greger Lindberg, MD,PhD Collapse <<
NCT00110968	Dyspepsia	Phase 3	Completed	-	-
NCT03698292	Critically-ill Patients	Not Applicable	Recruiting	September 2019	Egypt ... more >> Kasr Al Ainy Hospital Recruiting Cairo, Egypt Contact: Maha Hanna, MD 01227342966 mahagamil@hotmail.com Collapse <<
NCT00370110	Healthy	Phase 1 Phase 2	Completed	-	United States, Minnesota ... more >> Mayo Clinic College of Medicine Rochester, Minnesota, United States, 55905 Collapse <<

Itopride Catalog No. CSN11238

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