CAS No.: 1134822-07-3
Ivacaftor hydrate Catalog No. CSN17491
Synonyms: VX-770 hydrate
Ivacaftor is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
|---|
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Delaunay JL, Bruneau A, et al. Functional defect of variants in the adenosine triphosphate-binding sites of ABCB4 and their rescue by the cystic fibrosis transmembrane conductance regulator potentiator, ivacaftor (VX-770). Hepatology. 2017 Feb;65(2):560-570.
- [2] Mutyam V, Libby EF,et al.Therapeutic benefit observed with the CFTR potentiator, ivacaftor, in a CF patient homozygous for the W1282X CFTR nonsense mutation. J Cyst Fibros. 2017 Jan;16(1):24-29.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1134822-07-3 | 储存条件 |
|
|
| 分子式 | C24H30N2O4 | 运输 | 蓝冰 | |
| 分子量 | 410.51 | 别名 | VX-770 hydrate |
