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CAS No.: 75590-33-9

Kaerophyllin Catalog No. CSN14634

Synonyms: Chaerophyllin (6CI);(-)-Kaerophylin

Kaerophyllin, a natural product isolated and purified from the roots of Bupleurum chinense DC., protects the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting HSC activation, possibly through upregulation of PPAR-γ expression, and inhibits AB-induced LX-2 activation and migration with downregulation of Akt/ERK phosphorylations and NF-κB activity.

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技术信息

生物活性

描述Kaerophyllin, a natural product isolated and purified from the roots of Bupleurum chinense DC., protects the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting HSC activation, possibly through upregulation of PPAR-γ expression, and inhibits AB-induced LX-2 activation and migration with downregulation of Akt/ERK phosphorylations and NF-κB activity.
参考文献

[1] Lee TF, Lin YL, Huang YT. Protective effects of kaerophyllin against liver fibrogenesis in rats. Eur J Clin Invest. 2012 Jun;42(6):607-16.
[2] Lee TF, Lin YL, Huang YT. Kaerophyllin inhibits hepatic stellate cell activation by apoptotic bodies from hepatocytes. Liver Int. 2011 May;31(5):618-29.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.7146 mL
- 13.5729 mL
- 27.1459 mL
- 5 mM
- 0.5429 mL
- 2.7146 mL
- 5.4292 mL
- 10 mM
- 0.2715 mL
- 1.3573 mL
- 2.7146 mL

技术信息

CAS号	75590-33-9	储存条件	粉末液体 -20°C:3-6 月 -80°C:12月
分子式	C21H20O6	运输	蓝冰
分子量	368.38	别名	Chaerophyllin (6CI);(-)-Kaerophylin

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Kaerophyllin Catalog No. CSN14634

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