CAS No.: 1380424-42-9
KML29 Catalog No. CSN17769
Synonyms: KML29
KML29 is a highly selective and potent MAGL inhibitor with IC50s for 15, 43, and 5.9 nM in mouse, rat, and human brain proteomes, respectively.
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400-920-2911
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Ignatowska-Jankowska BM, Ghosh S, et al. In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects. Br J Pharmacol. 2014 Mar;171(6):1392-407.
- [2] Chang JW, Niphakis MJ, et al. Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates. Chem Biol. 2012 May 25;19(5):579-88.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1380424-42-9 | 储存条件 |
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| 分子式 | C24H21F6NO7 | 运输 | 蓝冰 | |||||
| 分子量 | 549.42 | 别名 | KML29 | |||||
| 溶解度 |
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动物实验配方 |
