CAS No.: 1333151-73-7
KPT-185 Catalog No. CSN17700
KPT-185 is a selective CRM1 inhibitor that induces growth inhibition and apoptosis in a panel of NHL cell lines with a median IC50 ~25 nM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Tabe Y, Kojima K, et al. Ribosomal Biogenesis and Translational Flux Inhibition by the Selective Inhibitor of Nuclear Export (SINE) XPO1 Antagonist KPT-185. PLoS One. 2015 Sep 4;10(9):e0137210.
- [2] Ranganathan P, Yu X, et al. Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia. Blood. 2012 Aug 30;120(9):1765-73.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1333151-73-7 | 储存条件 |
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| 分子式 | C16H16F3N3O3 | 运输 | 蓝冰 | |
| 分子量 | 355.31 | 别名 |
