400-920-2911 sales@csnpharm.cn
您的位置 : 首页 / PI3K/Akt/mTOR / PI3K / KU-0060648
CAS No.: 881375-00-4
Synonyms: Ku-0060648
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, and with less inhibition of PI3Kγ with IC50 of 0.59 μM.
生物活性
实验方案
技术信息
CAS号 | 881375-00-4 | 储存条件 |
|
|
分子式 | C33H34N4O4S | 运输 | 蓝冰 | |
分子量 | 582.71 | 别名 | Ku-0060648 |
Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
---|
human HeLa cells | - | Function assay | - | Inhibition of DNA-PK autophosphorylation at S2056 in human HeLa cells, EC50=0.136 μM | 23855836 |
MO59J-Fus1 cells | 1 μM | Function assay | - | Inhibition of human DNA-PK autophosphorylation at S2056 in MO59J-Fus1 cells at 1 uM | 23855836 |
联系我们
官方电话:400-920-2911
二维码
微信公众号 CSN官网