CAS No.: 84057-84-1
Lamotrigine/拉莫三嗪 Catalog No. CSN12998
Synonyms: LTG;BW430C;Lamictal
Lamotrigine is a member of the sodium channel blocking class of antiepileptic drugs which can block L-, N-, and P-type calcium channels and has weak 5-HT3 receptor inhibition.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00206778 Mixed Mania Bipolar Disorder Phase 2 Completed - United States, New York ... more >> Beth Israel Medical Center New York, New York, United States, 10003 Collapse << NCT00104416 Epilepsy, Tonic-Clonic Phase 3 Completed - - NCT02283801 Epilepsy Phase 1 Completed - - - 更多
- 参考文献
- [1] Goa KL, Ross SR, et al. Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy. Drugs. 1993 Jul;46(1):152-76.
- [2] Leach MJ, Marden CM, et al. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia. 1986 Sep-Oct;27(5):490-7.
- [3] Lovrić M, Čajić I, Petelin Gadže Ž, Klarica Domjanović I, Božina N. Effect of antiepileptic drug comedication on lamotrigine concentrations. Croat Med J. 2018 Feb 28;59(1):13-19.
- [4] Kim KJ, Jeun SH, Sung KW. Lamotrigine, an antiepileptic drug, inhibits 5-HT3 receptor currents in NCB-20 neuroblastoma cells. Korean J Physiol Pharmacol. 2017 Mar;21(2):169-177.
- [5] Jun IG, Kim SH, Yoon YI, Park JY. Intrathecal lamotrigine attenuates antinociceptive morphine tolerance and suppresses spinal glial cell activation in morphine-tolerant rats. J Korean Med Sci. 2013 Feb;28(2):300-7.
- [6] Wang K, Fernandez-Escobar A, Han S, Zhu P, Wang JH, Sun Y. Lamotrigine Reduces Inflammatory Response and Ameliorates Executive Function Deterioration in an Alzheimer's-Like Mouse Model. Biomed Res Int. 2016;2016:7810196
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 84057-84-1 | 储存条件 |
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| 分子式 | C9H7Cl2N5 | 运输 | 蓝冰 | |||||
| 分子量 | 256.09 | 别名 | LTG;BW430C;Lamictal;Crisomet;Lamictin;Lamitor;拉莫三嗪 | |||||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT00206778 | Mixed Mania Bipolar Disorder | Phase 2 | Completed | - | United States, New York ... more >> Beth Israel Medical Center New York, New York, United States, 10003 Collapse << |
| NCT00104416 | Epilepsy, Tonic-Clonic | Phase 3 | Completed | - | - |
| NCT02283801 | Epilepsy | Phase 1 | Completed | - | - |
| NCT00188643 | Bipolar Disorder | Phase 4 | Completed | - | Canada, Ontario ... more >> Toronto Western Hospital Toronto, Ontario, Canada, M5T2S8 Collapse << |
| NCT00104416 | - | - | Completed | - | - |
| NCT00723450 | Bipolar Disorder | Phase 3 | Completed | - | - |
| NCT00627575 | Epilepsy | Phase 1 | Completed | - | United States, New York ... more >> GSK Investigational Site Buffalo, New York, United States, 14202 Collapse << |
| NCT00264680 | - | - | Completed | - | - |
| NCT00723450 | - | - | Completed | - | - |
| NCT00321516 | Bipolar Disorder | Phase 1 | Completed | - | United States, Pennsylvania ... more >> Local Institution Philadelphia, Pennsylvania, United States United States, Texas Local Institution Austin, Texas, United States Local Institution Bellaire, Texas, United States Local Institution Desota, Texas, United States Collapse << |
| NCT00257855 | Secondary Progressive Multiple... more >> Sclerosis Collapse << | Phase 2 | Completed | - | United Kingdom ... more >> National Hospital for Neurology and Neurosurgery London, United Kingdom, WC1 3BG Collapse << |
| NCT00939458 | Healthy | Phase 1 | Completed | - | India ... more >> Lotus Labs Pvt. Ltd. Bangalore, Karnataka, India Collapse << |
| NCT01142310 | Memory Impairment | Phase 4 | Completed | - | United States, Texas ... more >> Parkland Health and Hospital System (Asthma, Allergy, & Arthritis Clinics) Dallas, Texas, United States, 75235 Collapse << |
| NCT01055327 | - | - | Completed | - | - |
| NCT00226135 | Bipolar Disorder | Phase 3 | Completed | - | Denmark ... more >> Aarhus University Psychiatric Hospital Risskov, Denmark, 8240 Collapse << |
| NCT01428518 | - | - | Completed | - | - |
| NCT00203229 | Trigeminal Neuralgia | Not Applicable | Completed | - | United States, Pennsylvania ... more >> Jefferson Headache Center Philadelphia, Pennsylvania, United States, 19107 Collapse << |
| NCT00203229 | - | - | Completed | - | - |
| NCT00153244 | Bronchial Asthma | Phase 4 | Completed | - | - |
| NCT00264615 | Epilepsy | Phase 3 | Completed | - | United States, Alabama ... more >> GSK Investigational Site Anniston, Alabama, United States, 36207 United States, Arizona GSK Investigational Site Sun City, Arizona, United States, 85351 United States, Kentucky GSK Investigational Site Lexington, Kentucky, United States, 40503 GSK Investigational Site Lexington, Kentucky, United States, 40536-0284 United States, Massachusetts GSK Investigational Site Boston, Massachusetts, United States, 02215 United States, Nevada GSK Investigational Site Reno, Nevada, United States, 89521 United States, New York GSK Investigational Site New York, New York, United States, 10016 United States, Ohio GSK Investigational Site Toledo, Ohio, United States, 43614-5809 United States, Pennsylvania GSK Investigational Site Philadelphia, Pennsylvania, United States, 19140 United States, Tennessee GSK Investigational Site Nashville, Tennessee, United States, 37232 United States, Texas GSK Investigational Site Dallas, Texas, United States, 75230 United States, Virginia GSK Investigational Site Richmond, Virginia, United States, 23219 Collapse << |
| NCT00650208 | Healthy | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
| NCT00647751 | Healthy | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
| NCT00068445 | Neurotoxicity ... more >> Pain Unspecified Adult Solid Tumor, Protocol Specific Collapse << | Phase 3 | Completed | - | - |
| NCT01015586 | Alcohol Dependence ... more >> Bipolar Disorder Depression Mania Psychosis Collapse << | Phase 4 | Unknown | May 2014 | United States, South Carolina ... more >> Clinical Neuroscience Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina Recruiting Charleston, South Carolina, United States, 29425 Contact: Bryan K Tolliver, M.D., Ph.D. 843-792-5215 tollive@musc.edu Collapse << |
| NCT01142310 | - | - | Completed | - | - |
| NCT00360126 | Bipolar Disorder | Phase 4 | Completed | - | Australia, New South Wales ... more >> GSK Investigational Site Greenwich, New South Wales, Australia, 2065 Australia, Queensland GSK Investigational Site Everton Park, Queensland, Australia, 4053 GSK Investigational Site New Farm, Queensland, Australia, 4005 Collapse << |
| NCT00068445 | - | - | Completed | - | - |
| NCT00939614 | Healthy | Phase 1 | Completed | - | India ... more >> Lotus Labs Pvt. Ltd. Bangalore, Karnataka, India, 560 052 Collapse << |
| NCT00360126 | - | - | Completed | - | - |
| NCT00652171 | Depression | Phase 3 | Completed | - | - |
| NCT00579982 | Mood Disorders | Phase 3 | Completed | - | United States, California ... more >> GSK Investigational Site San Diego, California, United States, 92108 GSK Investigational Site Santa Ana, California, United States, 92705 United States, Florida GSK Investigational Site Jacksonville, Florida, United States, 32257 GSK Investigational Site Orange City, Florida, United States, 32763 GSK Investigational Site Winter Park, Florida, United States, 32792 United States, Georgia GSK Investigational Site Marietta, Georgia, United States, 30060 United States, Illinois GSK Investigational Site Fairview Heights, Illinois, United States, 62208 United States, Minnesota GSK Investigational Site Minneapolis, Minnesota, United States, 55454 United States, Missouri GSK Investigational Site St. Charles, Missouri, United States, 63301 United States, New York GSK Investigational Site Olean, New York, United States, 14760 United States, North Carolina GSK Investigational Site Raleigh, North Carolina, United States, 27609 United States, Ohio GSK Investigational Site Cincinnati, Ohio, United States, 45243 GSK Investigational Site Cleveland, Ohio, United States, 44106 United States, Texas GSK Investigational Site Arlington, Texas, United States, 76012 GSK Investigational Site Houston, Texas, United States, 77014 GSK Investigational Site Houston, Texas, United States, 77042 United States, Virginia GSK Investigational Site Norfolk, Virginia, United States, 23505 United States, West Virginia GSK Investigational Site Charleston, West Virginia, United States, 25301 Collapse << |
| NCT00579982 | - | - | Completed | - | - |
| NCT00280293 | Bipolar Disorder ... more >> Cocaine Dependence Collapse << | Phase 4 | Completed | - | United States, Texas ... more >> UT Southwestern Medical Center at Dallas Dallas, Texas, United States, 75390-8849 Collapse << |
| NCT00224510 | Bipolar Disorder ... more >> Bipolar Depression Collapse << | Phase 3 | Completed | - | Netherlands ... more >> GSK Investigational Site Alkmaar, Netherlands, 1815 JD GSK Investigational Site Almelo, Netherlands, 7609 PP GSK Investigational Site Amersfoort, Netherlands, 3818 EW GSK Investigational Site Amsterdam, Netherlands, 1061 AE GSK Investigational Site Amsterdam, Netherlands, 1075 GB GSK Investigational Site Bennebroek, Netherlands, 2121 AD GSK Investigational Site Blaricum, Netherlands, 1261 AN GSK Investigational Site Delft, Netherlands, 2625 AD GSK Investigational Site Den Haag, Netherlands, 2553 RJ GSK Investigational Site Dordrecht, Netherlands, 3317 NM GSK Investigational Site Eindhoven, Netherlands, 5623 EJ GSK Investigational Site Enschede, Netherlands, 7511JX GSK Investigational Site Gouda, Netherlands, 2803 RT GSK Investigational Site Groningen, Netherlands, 9713 GZ GSK Investigational Site Hoorn, Netherlands, 1624 NP GSK Investigational Site Leiden, Netherlands, 2333 ZB GSK Investigational Site Nijmegen, Netherlands, 6532 SZ GSK Investigational Site Raalte, Netherlands, 8102 RR GSK Investigational Site Retranchement, Netherlands, 4525 LG GSK Investigational Site Rosmalen, Netherlands, 5248 NT GSK Investigational Site Tilburg, Netherlands, 5022 GC GSK Investigational Site Utrecht, Netherlands, 3512 PG GSK Investigational Site Vlissingen, Netherlands, 4382 EE GSK Investigational Site Weert, Netherlands, 6001 BE GSK Investigational Site Zwolle, Netherlands, 8025 AB Spain GSK Investigational Site Alava, Spain, 01004 GSK Investigational Site Barcelona, Spain, 08025 GSK Investigational Site Barcelona, Spain, 08035 GSK Investigational Site Barcelona, Spain, 08036 GSK Investigational Site Madrid, Spain, 28035 GSK Investigational Site Valencia, Spain, 46009 Collapse << |
| NCT00277212 | - | - | Completed | - | - |
| NCT00280293 | - | - | Completed | - | - |
| NCT01431976 | Epilepsy | Phase 3 | Completed | - | Japan ... more >> GSK Investigational Site Aichi, Japan, 453-8511 GSK Investigational Site Ehime, Japan, 790-8524 GSK Investigational Site Ehime, Japan, 791-0295 GSK Investigational Site Fukuoka, Japan, 807-8555 GSK Investigational Site Fukuoka, Japan, 814-0180 GSK Investigational Site Hiroshima, Japan, 730-8518 GSK Investigational Site Hokkaido, Japan, 006-0041 GSK Investigational Site Hokkaido, Japan, 060-8648 GSK Investigational Site Kanagawa, Japan, 232-8555 GSK Investigational Site Niigata, Japan, 950-2085 GSK Investigational Site Okayama, Japan, 700-8558 GSK Investigational Site Shizuoka, Japan, 430-8558 GSK Investigational Site Tokyo, Japan, 113-8603 Korea, Republic of GSK Investigational Site Seoul, Korea, Republic of, 120-752 Collapse << |
| NCT01431976 | - | - | Completed | - | - |
| NCT01607086 | Mental Disorders | Phase 1 | Completed | - | United Kingdom ... more >> GSK Investigational Site Cambridge, Cambridgeshire, United Kingdom, CB2 0QQ Collapse << |
| NCT01431963 | Epilepsy | Phase 3 | Completed | - | Japan ... more >> GSK Investigational Site Fukuoka, Japan, 807-8555 GSK Investigational Site Ibaraki, Japan, 317-0077 GSK Investigational Site Kagoshima, Japan, 892-0844 GSK Investigational Site Kyoto, Japan, 611-0042 GSK Investigational Site Miyagi, Japan, 980-8574 GSK Investigational Site Nara, Japan, 634-8522 GSK Investigational Site Niigata, Japan, 950-1197 GSK Investigational Site Niigata, Japan, 950-2085 GSK Investigational Site Okayama, Japan, 703-8265 GSK Investigational Site Osaka, Japan, 560-8565 GSK Investigational Site Shizuoka, Japan, 430-8558 Korea, Republic of GSK Investigational Site Seoul, Korea, Republic of, 110-744 GSK Investigational Site Seoul, Korea, Republic of, 135-710 Collapse << |
| NCT00242606 | Epilepsy | Phase 3 | Completed | - | Germany ... more >> Philipps University Marburg Medical Center, Department of Neurology Marburg, Germany, 35033 Collapse << |
| NCT00410371 | Mental Disorders | Phase 1 | Completed | - | United States, Nebraska ... more >> GSK Investigational Site Lincoln, Nebraska, United States, 68502 Collapse << |
| NCT01431963 | - | - | Completed | - | - |
| NCT00277212 | Bipolar Disorder | Phase 4 | Completed | - | - |
| NCT00513019 | - | - | Completed | - | - |
| NCT00513019 | Neurotic Excoriation ... more >> Pathologic Skin Picking Psychogenic Excoriation Dermatillomania Collapse << | Phase 2 | Completed | - | United States, Minnesota ... more >> Ambulatory Research Center Minneapolis, Minnesota, United States, 55454 Collapse << |
| NCT00947375 | Schizophrenia | Phase 4 | Terminated(All of the mentione... more >>d aim and objectives were achieved before the February 2007) Collapse << | - | Azerbaijan ... more >> Central Mental Clinic for Outpatients of Baku City Baku, Azerbaijan, AZ0010 Collapse << |
| NCT00266149 | Epilepsy | Phase 3 | Terminated | - | Denmark ... more >> Department of Neurology, Aarhus University Hospital Aarhus, Denmark, 8000 Collapse << |
| NCT01863602 | - | - | Completed | - | - |
| NCT00277641 | Binge Eating Disorder ... more >> Obesity Collapse << | Phase 3 | Completed | - | United States, Ohio ... more >> Lindner Center of HOPE Mason, Ohio, United States, 45040 Collapse << |
| NCT00901407 | Unipolar Depression | Not Applicable | Completed | - | United States, Louisiana ... more >> LSUHSC- New Orleans New Orleans, Louisiana, United States, 70115 Collapse << |
| NCT00634062 | Borderline Personality Disorde... more >>r Collapse << | Phase 4 | Completed | - | United States, Massachusetts ... more >> McLean Hospital Belmont, Massachusetts, United States, 02478 Collapse << |
| NCT00917839 | Relapsing-Remitting Multiple S... more >>clerosis Collapse << | Phase 2 | Unknown | December 2011 | Switzerland ... more >> Cantonal Hospital St. Gallen Recruiting St. Gallen, Switzerland, 9007 Contact: Norman Putzki, MD +4171494 ext 1663 norman.putzki@kssg.ch Principal Investigator: Norman Putzki, MD Sub-Investigator: Ozgur Yaldizli, MD Collapse << |
| NCT00838136 | - | - | Completed | - | - |
| NCT00838279 | - | - | Completed | - | - |
| NCT00835263 | - | - | Completed | - | - |
| NCT00834561 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Anapharm Inc. Sainte-Foy, Quebec, Canada, G1V 2K8 Collapse << |
| NCT00838279 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Anapharm Inc. Sainte-Foy, Quebec, Canada, GIV2K8 Collapse << |
| NCT00834561 | - | - | Completed | - | - |
| NCT00835263 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Anapharm Inc. Sainte-Foy, Quebec, Canada, G1V 2K8 Collapse << |
| NCT00460226 | - | - | Completed | - | - |
| NCT01618799 | Fasting State | Phase 1 | Completed | - | India ... more >> Cliantha Research Limited Ahmedabad, Gujarat, India Collapse << |
| NCT00838136 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... more >> Anapharm Inc. Sainte-Foy, Quebec, Canada, GIV2K8 Collapse << |
| NCT00550407 | - | - | Completed | - | - |
| NCT00412191 | Epilepsy | Phase 1 | Completed | - | Germany ... more >> GSK Investigational Site Berlin, Germany, 14050 Collapse << |
| NCT01618825 | Fed | Phase 1 | Completed | - | India ... more >> Cliantha Research Limited Ahmedabad, Gujarat, India Collapse << |
| NCT00550407 | Bipolar Disorder | Phase 3 | Completed | - | - |
| NCT00355082 | Epilepsy, Partial | Phase 3 | Completed | - | - |
| NCT00516139 | - | - | Completed | - | - |
| NCT00355082 | - | - | Completed | - | - |
| NCT02100644 | - | - | Completed | - | - |
| NCT00566020 | Bipolar Disorder | Phase 3 | Completed | - | - |
| NCT01064297 | - | - | Completed | - | - |
| NCT00516139 | Epilepsy | Phase 3 | Completed | - | - |
| NCT01064297 | - | - | Completed | - | - |
| NCT02100644 | Epilepsy | Phase 4 | Completed | - | Japan ... more >> GSK Investigational Site Hyogo, Japan, 664-8540 GSK Investigational Site Kagoshima, Japan, 892-0844 GSK Investigational Site Kyoto, Japan, 606-8507 GSK Investigational Site Osaka, Japan, 560-8565 GSK Investigational Site Saitama, Japan, 351-8551 GSK Investigational Site Shizuoka, Japan, 430-8558 GSK Investigational Site Tokyo, Japan, 185-0012 Collapse << |
| NCT00913107 | Trigeminal Neuralgia | Phase 2 Phase 3 | Completed | - | Malaysia ... more >> Dept. of OMOP, Faculty of Dentistry, University Malaya. Kuala Lumpur, Malaysia, 50603 Dept. of Oral Medicine and Oral Pathology, Faculty of Dentistry, University Malaya. Kuala Lumpur, Malaysia, 50603 Collapse << |
| NCT01602510 | Bipolar Disorder | Phase 3 | Completed | - | China, Guangdong ... more >> GSK Investigational Site Guangzhou, Guangdong, China, 510180 GSK Investigational Site Guangzhou, Guangdong, China, 510370 GSK Investigational Site Guangzhou, Guangdong, China, 510630 China, Hebei GSK Investigational Site Baoding, Hebei, China, 071000 GSK Investigational Site Shijiazhuang, Hebei, China, 050000 China, Heilongjiang GSK Investigational Site Harbin, Heilongjiang, China, 150070 China, Henan GSK Investigational Site Changsha, Henan, China, 410011 GSK Investigational Site Xinxiang, Henan, China China, Hubei GSK Investigational Site Wuhan, Hubei, China, 430022 China, Hunan GSK Investigational Site Changsha, Hunan, China China, Jiangsu GSK Investigational Site Nanjing, Jiangsu, China, 210029 China, Shaanxi GSK Investigational Site Xi'an, Shaanxi, China, 710032 China, Shanxi GSK Investigational Site Taiyuan, Shanxi, China China, Sichuan GSK Investigational Site Chengdu, Sichuan, China, 610041 China, Yunnan GSK Investigational Site Kunming, Yunnan, China, 650032 China, Zhejiang GSK Investigational Site Hangzhou, Zhejiang, China, 310003 GSK Investigational Site Hangzhou, Zhejiang, China, 310009 China GSK Investigational Site Beijing, China, 100083 GSK Investigational Site Beijing, China, 100088 GSK Investigational Site Beijing, China, 100096 GSK Investigational Site Shanghai, China, 200030 Collapse << |
| NCT01376180 | - | - | Completed | - | - |
| NCT02404168 | Epilepsy | Phase 4 | Unknown | December 2015 | United States, Maryland ... more >> University of Maryland Baltimore, Maryland, United States, 21201 Collapse << |
| NCT00618241 | HIV Infection | Phase 1 | Completed | - | Netherlands ... more >> Radboud University Medical Center Nijmegen, Gelderland, Netherlands Collapse << |
| NCT00566020 | - | - | Completed | - | - |
| NCT01888250 | Healthy | Phase 1 | Completed | - | India ... more >> Bioserve Clinical Research Private Limited Balanagar, Hyderabad, India, 500 037 Collapse << |
| NCT01888731 | Healthy | Phase 1 | Completed | - | India ... more >> Bioserve Clinical Research Private Limited Balanagar, Hyderabad, India, 500 037 Collapse << |
| NCT00605371 | Epilepsy | Phase 1 | Completed | - | United States, Washington ... more >> GSK Investigational Site Tacoma, Washington, United States, 98418 Collapse << |
| NCT00181844 | Bipolar Disorder ... more >> Mania Collapse << | Phase 4 | Completed | - | United States, Massachusetts ... more >> Massachusetts General Hospital Cambridge, Massachusetts, United States, 02138 Collapse << |
| NCT01888263 | Healthy | Phase 1 | Completed | - | India ... more >> Bioserve Clinical Research Private Limited Balanagar, Hyderabad, India, 500 037 Collapse << |
| NCT00181844 | - | - | Completed | - | - |
| NCT00144872 | Seizure, Absence | Phase 1 | Completed | - | United States, California ... more >> GSK Investigational Site San Jose, California, United States, 95128 United States, Florida GSK Investigational Site Loxahatchee Groves, Florida, United States, 33470 GSK Investigational Site Melbourne, Florida, United States, 32901 GSK Investigational Site Panama City, Florida, United States, 32405 GSK Investigational Site Tallahassee, Florida, United States, 32308 GSK Investigational Site Tampa, Florida, United States, 33607-6350 United States, Georgia GSK Investigational Site Atlanta, Georgia, United States, 30342 United States, Kentucky GSK Investigational Site Louisville, Kentucky, United States, 40202 United States, Missouri GSK Investigational Site Springfield, Missouri, United States, 65804 United States, New Jersey GSK Investigational Site Newark, New Jersey, United States, 07103 United States, New York GSK Investigational Site Buffalo, New York, United States, 14222 GSK Investigational Site Rochester, New York, United States, 14642 United States, North Carolina GSK Investigational Site Chapel Hill, North Carolina, United States, 27599-7600 GSK Investigational Site Greenville, North Carolina, United States, 27834 GSK Investigational Site Raleigh, North Carolina, United States, 27607 United States, Oregon GSK Investigational Site Portland, Oregon, United States, 97239 United States, Tennessee GSK Investigational Site Germantown, Tennessee, United States, 38138 GSK Investigational Site Nashville, Tennessee, United States, 37212 United States, Texas GSK Investigational Site Fort Worth, Texas, United States, 76104 United States, Washington GSK Investigational Site Seattle, Washington, United States, 98105 United States, Wisconsin GSK Investigational Site Madison, Wisconsin, United States, 53792 GSK Investigational Site Milwaukee, Wisconsin, United States, 53215 GSK Investigational Site Milwaukee, Wisconsin, United States, 53226 Collapse << |
| NCT01888757 | Healthy | Phase 1 | Completed | - | India ... more >> Bioserve Clinical Research Private Limited Balanagar, Hyderabad, India, 500 037 Collapse << |
| NCT01357902 | Epilepsy | Phase 1 | Completed | - | Hong Kong ... more >> GSK Investigational Site Shatin, New Territories, Hong Kong Collapse << |
| NCT01602510 | - | - | Completed | - | - |
| NCT00720473 | - | - | Completed | - | - |
| NCT00720473 | Bipolar Depression | Not Applicable | Completed | - | United States, Massachusetts ... more >> McLean Hospital Belmont, Massachusetts, United States, 02478 Collapse << |
| NCT01657864 | - | - | Completed | - | - |
| NCT00176228 | - | - | Completed | - | - |
| NCT00243152 | Facial Neuropathy | Not Applicable | Completed | - | United States, Massachusetts ... more >> McLean Hospital Neuroimaging Center, 115 Mill Street Belmont, Massachusetts, United States, 02478 Collapse << |
| NCT03419949 | - | - | - | - | Egypt ... more >> Salma Komy Assiut, Egypt Collapse << |
| NCT00176228 | Bipolar Disorder | Phase 2 | Completed | - | United States, Illinois ... more >> NPI, University of Illinois at Chicago Chicago, Illinois, United States, 60612 Collapse << |
| NCT00896987 | Epilepsy | Phase 4 | Completed | - | Korea, Republic of ... more >> Asan Medical Center Seoul, Korea, Republic of Collapse << |
| NCT01042496 | Bipolar Depression | Phase 3 | Completed | - | United States, Minnesota ... more >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 Collapse << |
| NCT01042496 | - | - | Completed | - | - |
| NCT00621842 | Bipolar Disorder ... more >> Depression, Bipolar Collapse << | Phase 3 | Completed | - | United States, New York ... more >> Weill Medical College of Cornell University White Plains, New York, United States, 10605 United States, Ohio University Hospitals Case Medical Center/ Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic Pittsburgh, Pennsylvania, United States, 15213 United States, Texas Baylor College of Medicine/Michael E. DeBakey VAMC Houston, Texas, United States, 77030 Collapse << |
| NCT01864551 | Bipolar Disorder | Phase 4 | Completed | - | Taiwan ... more >> Tri-Service General Hospital Taipei, Taiwan, 114 Collapse << |
| NCT00243152 | - | - | Completed | - | - |
| NCT00449774 | Mental Disorders | Phase 1 | Completed | - | United States, Texas ... more >> GSK Investigational Site Dallas, Texas, United States, 75247 Collapse << |
| NCT02556060 | Addiction | Phase 2 Phase 3 | Completed | - | Taiwan ... more >> Taipei City Hospital and Psychiatric Center Taipei, Taiwan, 110 Collapse << |
| NCT00621842 | - | - | Completed | - | - |
| NCT02389712 | Bipolar Disorder | Phase 4 | Completed | - | United States, Minnesota ... more >> Mayo Clinic Rochester, Minnesota, United States, 55905 Collapse << |
| NCT01513720 | Healthy | Phase 1 | Completed | - | United States, North Carolina ... more >> AAI Clinic Quadrangle drive, North Carolina, United States, 27514 Collapse << |
| NCT00789113 | - | - | Completed | - | - |
| NCT01513681 | Healthy | Phase 1 | Completed | - | United States, North Carolina ... more >> AAI Clinic Quadrangle drive, North Carolina, United States, 27514 Collapse << |
| NCT00789113 | Epilepsy Seiz... more >>ures Bipolar Disorder Bipolar Depression Collapse << | Phase 1 Phase 2 | Completed | - | United States, Minnesota ... more >> University of Minnesota Minneapolis, Minnesota, United States, 55404 Collapse << |
| NCT02256124 | Neurofibromatosis Type 1 | Phase 2 Phase 3 | Recruiting | July 2019 | Belgium ... more >> University Hospital Leuven Recruiting Leuven, Belgium, B-3000 Contact: Eric Legius, MD, PhD +3216345903 eric.legius@uzleuven.be Contact: Ellen Plasschaert, MSc +3216345903 ellen.plasschaert@uzleuven.be Sub-Investigator: Ellen Plasschaert, MSc Principal Investigator: Eric Legius, MD, PhD Netherlands Erasmus Medical Center Recruiting Rotterdam, South Holland, Netherlands, 3015CN Principal Investigator: Marie-Claire Y de Wit, MD, PhD Sub-Investigator: Myrthe Ottenhoff, MD, MSc Spain Hospital Sant Joan de Deu Recruiting Barcelona, Spain Contact: Hector Salvador Hernandez, Dr. Collapse << |
| NCT01131949 | Healthy | Phase 1 | Completed | - | United States, North Carolina ... more >> AAI Clinic Chapel Hill, North Carolina, United States, 27514 Collapse << |
| NCT01939561 | Dystrophia Myotonica Type 1 ... more >> Myotonia Congenita Paramyotonia Congenita Hyperkalemic Periodic Paralysis Potassium-Aggravated Myotonia Collapse << | Phase 3 | Completed | - | Denmark ... more >> Copenhagen Neuromuscular Center, department of Neurology, Rigshospitalet Copenhagen, Denmark, DK-2100 Collapse << |
| NCT02158585 | Meniere's Disease ... more >> Ménière's Vertigo Vertigo, Intermittent Vertigo, Aural Collapse << | Phase 3 | Completed | - | United States, New York ... more >> Dent Neurologic Institute Amherst, New York, United States, 14226 Collapse << |
| NCT01879423 | Epilepsy | Phase 1 | Completed | - | China ... more >> GSK Investigational Site Shanghai, China, 200030 Collapse << |
| NCT02989727 | Depression Bi... more >>polar Disorder Bipolar Depression Melancholia Lamotrigine Collapse << | Phase 4 | Unknown | November 2017 | Canada, Saskatchewan ... more >> Department of Psychiatry, Royal University Hospital Saskatoon, Saskatchewan, Canada, S7N0W8 Collapse << |
| NCT01131975 | Healthy | Phase 1 | Completed | - | United States, North Carolina ... more >> AAI Clinic Chapel Hill, North Carolina, United States, 27514 Collapse << |
| NCT01995825 | Epilepsy | Phase 4 | Completed | - | United States, Maryland ... more >> University of Maryland Baltimore, Maryland, United States, 21201 Collapse << |
| NCT03497143 | - | - | Recruiting | October 2026 | Norway ... more >> St. Olavs University Hospital Recruiting Trondheim, Norway Contact: Magnus Strømmen, MSc Collapse << |
| NCT02303106 | Healthy | Phase 4 | Completed | - | Denmark ... more >> University of Southern Denmark Odense, Denmark, 5210 Collapse << |
| NCT00475137 | Bipolar II Disorder, Most Rece... more >>nt Episode Major Depressive Collapse << | Phase 2 | Completed | - | Canada, British Columbia ... more >> University of British Columbia Mood Disorders Centre Vancouver, British Columbia, Canada Collapse << |
| NCT02513654 | Bipolar Disorder | Phase 1 | Completed | - | China ... more >> GSK Investigational Site Shanghai, China, 200030 Collapse << |
| NCT03220256 | Lamotrigine Allergy | Phase 2 | Recruiting | August 1, 2018 | Korea, Republic of ... more >> Seoul National University Hospital Recruiting Seoul, Korea, Republic of Contact: Sang Kun Lee, MD, PhD sangkun2923@gmail.com Principal Investigator: Sang Kun Lee, MD, PhD Collapse << |
| NCT03774641 | - | - | Recruiting | December 31, 2020 | United States, Maryland ... more >> 550 N Broadway Recruiting Baltimore, Maryland, United States, 21205 Contact: Courtney N Erdly Principal Investigator: Jennifer L Payne, MD Collapse << |
| NCT01996293 | - | - | Unknown | September 2017 | United States, Illinois ... more >> Northwestern Memorial Hospital Recruiting Chicago, Illinois, United States, 60611 Contact: Crystal T Clark, MD, MSc 312-695-8648 crystal.clark@northwestern.edu Principal Investigator: Crystal T Clark, MD, MSc Collapse << |
| NCT02064465 | Epilepsy | Phase 1 | Completed | - | China ... more >> GSK Investigational Site Shanghai, China, 200030 Collapse << |
| NCT02821338 | Healthy | Phase 1 | Completed | - | United States, Kansas ... more >> Vince and Associates Clinical Research, Inc Overland Park, Kansas, United States, 66212 Collapse << |
| NCT02707965 | Epilepsy | Phase 4 | Completed | - | United States, Maryland ... more >> University of Maryland, Baltimore Baltimore, Maryland, United States, 21201 Collapse << |
| NCT00001478 | - | - | Completed | - | United States, Maryland ... more >> National Institute of Mental Health (NIMH) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00012558 | Bipolar Disorder | Not Applicable | Completed | - | United States, California ... more >> Stanford University School of Medicine Stanford, California, United States, 94305-5723 United States, Colorado University of Colorado, Colorado Psychiatric Health Clinical Investigation Center Denver, Colorado, United States, 80220 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States, 02114 University of Massachusetts Medical Center Worcester, Massachusetts, United States, 01655 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Oklahoma University of Oklahoma Health Sciences Center Tulsa, Oklahoma, United States, 74135 United States, Oregon Portland Veteran's Administration Medical Center Portland, Oregon, United States, 97201 United States, Pennsylvania University of Pennsylvania Medical Center Philadelphia, Pennsylvania, United States, 19104-2649 University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213 United States, Texas Baylor College of Medicine Houston, Texas, United States, 77030 University of Texas Health Science Center at San Antonio San Antonio, Texas, United States, 78229-3900 Collapse << |
| NCT00177567 | Bipolar Disorder | Phase 4 | Completed | - | United States, Pennsylvania ... more >> University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 University of Pittsubrgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT02374567 | Dementia Depr... more >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Collapse << | Phase 3 | Terminated | - | Germany ... more >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Collapse << |
| NCT00552526 | Epilepsy Ment... more >>al Retardation Collapse << | Phase 4 | Unknown | December 2013 | Norway ... more >> SSE, Nevrological dep. , Rikshospitalet University hospital Oslo, Norway Collapse << |
| NCT00404248 | Brain and Central Nervous Syst... more >>em Tumors Collapse << | Phase 1 Phase 2 | Completed | - | United States, Alabama ... more >> UAB Comprehensive Cancer Center Birmingham, Alabama, United States, 35294-3410 United States, Florida H. Lee Moffitt Cancer Center and Research Institute at University of South Florida Tampa, Florida, United States, 33612-9497 United States, Georgia Winship Cancer Institute of Emory University Atlanta, Georgia, United States, 30322 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States, 02114 United States, Michigan Josephine Ford Cancer Center at Henry Ford Hospital Detroit, Michigan, United States, 48202 United States, North Carolina Wake Forest University Comprehensive Cancer Center Winston-Salem, North Carolina, United States, 27157-1096 United States, Ohio Cleveland Clinic Taussig Cancer Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104-4283 Collapse << |
| NCT00068770 | Brain and Central Nervous Syst... more >>em Tumors Collapse << | Phase 2 | Terminated(EORTC trail showed ... more >>TMZ & RT conferred significant survivial in this population) Collapse << | - | United States, Florida ... more >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612-9497 United States, Georgia Winship Cancer Institute of Emory University Atlanta, Georgia, United States, 30322 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231-2410 United States, Massachusetts Massachusetts General Hospital Cancer Center Boston, Massachusetts, United States, 02114-2617 United States, North Carolina Comprehensive Cancer Center at Wake Forest University Winston-Salem, North Carolina, United States, 27157-1030 United States, Ohio Cleveland Clinic Taussig Cancer Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104-4283 Collapse << |
| NCT02205931 | Epilepsy | Phase 4 | Recruiting | June 2019 | United Kingdom ... more >> Birmingham Children's Hospital Recruiting Birmingham, United Kingdom, B4 6NH Contact: Shakti Agrawal, MBBS 0044 1213338149 shakti.agrawal@bch.nhs.uk Principal Investigator: Shakti Agrawal, MBBS Bristol Royal Hospital for Children Recruiting Bristol, United Kingdom, BS2 8AE Contact: Andrew Mallick, FRCPCH Principal Investigator: Andrew Mallick Addenbrooke's Hospital Recruiting Cambridge, United Kingdom, CB2 0QQ Contact: Alasdair Parker, MA 0044 1223 245151 alasdair.parker@addenbrookes.nhs.uk Principal Investigator: Alasdair Parker, MA Lancashire Teaching Hospitals NHS Foundation Trust Recruiting Lancashire, United Kingdom Contact: Helen Basu Helen.Basu@lthtr.nhs.uk Principal Investigator: Helen Basu Leeds Teaching Hospital Recruiting Leeds, United Kingdom, LS1 3EX Contact: Helen McCullagh, RCPCH 0044 113 243 2799 h.mccullagh@nhs.net Principal Investigator: Helen McCullagh, RCPCH Alder Hey Children's Hospital Recruiting Liverpool, United Kingdom, L12 2AP Contact: Rachel Kneen, BMBS 0044 151 2525163 rachel.kneen@liverpool.ac.uk Principal Investigator: Rachel Kneen, BMBS Great Ormond Street Hospital Recruiting London, United Kingdom, WC1N 3JH Contact: Christin Eltze, MD Res 0044 207 405 9200 ext 5438 christin.eltze@gosh.nhs.uk Principal Investigator: Christin Eltze, MD Res St George's University Hospitals NHS Foundation Trust Recruiting London, United Kingdom Contact: Penny Fallon Penny.Fallon@stgeorges.nhs.uk Principal Investigator: Penny Fallon Royal Manchester Children's Hospital Recruiting Manchester, United Kingdom, M13 0JE Contact: Tim Martland, RCPCH 0044 161 276 1234 timothy.martland@cmft.nhs.uk Principal Investigator: Tim Martland, RCPCH The Newcastle Upon Tyne Hospitals NHS Foundation Trust Recruiting Newcastle upon Tyne, United Kingdom Contact: Anita Devlin Anita.Devlin@nuth.nhs.uk Principal Investigator: Anita Devlin Sheffield Children's NHS Foundation Trust Recruiting Sheffield, United Kingdom Contact: Archana Desurkar Archana.Desurkar@sch.nhs.uk Principal Investigator: Archana Desurkar Collapse << |
| NCT02300051 | Compulsive Sexual Behavior | Not Applicable | Completed | - | Brazil ... more >> Instituto de Psiquiatria do Hospital das Clínicas da Universidade de São Paulo[University of Sao Paulo General Hospital] São Paulo, Brazil, 05403010 Collapse << |
| NCT01689389 | - | - | Completed | - | France ... more >> Research Site Argenteuil Cedex, France Research Site Belley, France Research Site Castelmaurou, France Reserach Site Cavaillon, France Research Site Les Mureaux, France Research Site Lille, France Research Site Marseille, France Research Site Montpellier, France Research Site Nimes Cedex, France Research SIte Obernai, France Research Site Paris, France Research Site Rennes, France Research Site Saintes Cedex, France Research Site Sens, France research Site St Dizier, France Research Site St Egreve Cedex, France Research Site Toulouse, France Research Site Tours, France Research Site Ussel Cedex, France Collapse << |
| NCT00404248 | - | - | Completed | - | - |
| NCT00068770 | - | - | Terminated(EORTC trail showed ... more >>TMZ & RT conferred significant survivial in this population) Collapse << | - | - |
