CAS No.: 1256388-51-8
Ledipasvir/雷迪帕韦 Catalog No. CSN13833
Synonyms: GS-5885;trade name: Harvoni;雷迪帕韦
Ledipasvir is the hepatitis C virus NS5A inhibitor with EC50 of 34 pM and 4 pM against GT1a and GT1b replicon.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02771405 Hepatitis C, Chronic ... more >> Hepatocellular Carcinoma Collapse << Phase 3 Recruiting September 2019 Egypt ... more >> Amr Maged Recruiting Cairo, Egypt, 11441 Contact: Amr Maged amrrasheed88@gmail.com Collapse << NCT03481036 Chronic Hepatitis c Not Applicable Recruiting December 31, 2020 India ... more >> Post Graduate Institute of Medical Education and Research Recruiting Chandigarh, India, 160012 Contact: Radha K Dhiman, DM 911722756335 rkpsdhiman@hotmail.com Collapse << NCT02609893 Chronic Hepatitis C Phase 4 Active, not recruiting May 2018 United States, California ... more >> Substance Use Research Unit San Francisco, California, United States, 94102 Collapse << - 更多
- 参考文献
- [1] Link JO, Taylor JG, et al. Discovery of ledipasvir (GS-5885): a potent, once-daily oral NS5A inhibitor for the treatment of hepatitis C virus infection. J Med Chem. 2014 Mar 13;57(5):2033-46.
- [2] Hernandez D, Zhou N, et al. Natural prevalence of NS5A polymorphisms in subjects infected with hepatitis C virus genotype 3 and their effects on the antiviral activity of NS5A inhibitors. J Clin Virol. 2013 May;57(1):13-8.
- [3] Link JO, Taylor JG, Xu L, Mitchell M, et al. Discovery of ledipasvir (GS-5885): a potent, once-daily oral NS5A inhibitor for the treatment of hepatitis C virus infection. J Med Chem. 2014 Mar 13;57(5):2033-46
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1256388-51-8 | 储存条件 |
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| 分子式 | C49H54F2N8O6 | 运输 | 蓝冰 | |||||||
| 分子量 | 889.00 | 别名 | GS-5885;trade name: Harvoni;雷迪帕韦 | |||||||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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| NCT02771405 | Hepatitis C, Chronic ... more >> Hepatocellular Carcinoma Collapse << | Phase 3 | Recruiting | September 2019 | Egypt ... more >> Amr Maged Recruiting Cairo, Egypt, 11441 Contact: Amr Maged amrrasheed88@gmail.com Collapse << |
| NCT03481036 | Chronic Hepatitis c | Not Applicable | Recruiting | December 31, 2020 | India ... more >> Post Graduate Institute of Medical Education and Research Recruiting Chandigarh, India, 160012 Contact: Radha K Dhiman, DM 911722756335 rkpsdhiman@hotmail.com Collapse << |
| NCT02609893 | Chronic Hepatitis C | Phase 4 | Active, not recruiting | May 2018 | United States, California ... more >> Substance Use Research Unit San Francisco, California, United States, 94102 Collapse << |
| NCT02555943 | Chronic Hepatitis C Infection ... more >> HBV Coinfection Hepatitis B Reactivation Collapse << | Phase 2 Phase 3 | Recruiting | December 2018 | China, Hong Kong ... more >> Humanity and Health GI and Liver Centre Recruiting Hong Kong, Hong Kong, China, 00852 Contact: Cheng Wang, M.D. PhD (852)28613777 doc_chengwang@126.com Contact: Yudong Wang (852)28613777 ydwang@connect.hku.hk Collapse << |
| NCT03488485 | Chronic Hepatitis c | Not Applicable | Recruiting | December 2020 | India ... more >> Post Graduate Institute of Medical Education and Research Recruiting Chandigarh, India, 160012 Contact: Radha K Dhiman, DM 911722756335 rkpsdhiman@hotmail.com Collapse << |
| NCT02573376 | HEPATITIS C V... more >>irus, Human Immunodeficiency Collapse << | Not Applicable | Recruiting | March 2021 | United States, Colorado ... more >> University of Colorado Anschutz Medical Campus Recruiting Aurora, Colorado, United States, 80045 Contact: Ryan T Huntley, BS 303-724-5564 ryan.huntley@ucdenver.edu Collapse << |
| NCT01726517 | Chronic Hepatitis C Virus | Phase 2 | Completed | - | United States, Texas ... more >> San Antonio, Texas, United States, 78215 Collapse << |
| NCT03169348 | Hepatitis C | Not Applicable | Recruiting | September 2019 | Egypt ... more >> Assiut University Recruiting Assiut, Egypt, 71111 Contact: Ahmed Abbas, MD 00201003385183 bmr90@hotmail.com Collapse << |
| NCT02951364 | - | - | Recruiting | October 2021 | - |
| NCT01726517 | - | - | Completed | - | - |
| NCT03402165 | Hepatitis C | Phase 4 | Recruiting | December 30, 2022 | Egypt ... more >> Sherief Abd-Elsalam Recruiting Tanta, Egypt Contact: Sherief Abd-elsalam, lecturer 00201000040794 Sherif_tropical@yahoo.com Collapse << |
| NCT02469012 | Hepatitis C, Chronic | Not Applicable | Unknown | April 2017 | Germany ... more >> Kreiskliniken Altötting-Burghausen, Medizinische Klinik II Recruiting Burghausen, Bavaria, Germany, 84489 Contact: Michael R Kraus, MD, PhD +4986778801 ext 41 m.kraus@krk-bgh.de Collapse << |
| NCT02825212 | Hepatitis C C... more >>ryoglobulinemia Collapse << | Phase 2 Phase 3 | Recruiting | December 2018 | United States, New York ... more >> Icahn School of Medicine at Mount Sinai Recruiting New York, New York, United States, 10029 Contact: Peter Gorevic, MD 212-241-0968 peter.gorevic@mountsinai.org Contact: Susana Seijo, MD-Spain 212-241-1617 susana.seijo@mssm.edu Principal Investigator: Peter Gorevic, MD Collapse << |
| NCT02786537 | Chronic Hepatitis C | Phase 4 | Active, not recruiting | February 2022 | - |
| NCT03063723 | - | - | Completed | - | - |
| NCT02128217 | HIV-1 Infection ... more >> Hepatitis Collapse << | Phase 1 | Completed | - | United States, California ... more >> 701 University of California, San Diego AntiViral Research Center CRS San Diego, California, United States, 92103 801 University of California, San Francisco HIV/AIDS CRS San Francisco, California, United States, 94110 United States, District of Columbia Whitman Walker Health CRS (31791) Washington, District of Columbia, United States, 20009 United States, Illinois 2701 Northwestern University CRS Chicago, Illinois, United States, 60611 Rush Univ. Med. Ctr. ACTG CRS (2702) Chicago, Illinois, United States, 60612 United States, Massachusetts 101 Massachusetts General Hospital (MGH) CRS Boston, Massachusetts, United States, 02114 United States, New York 7804 Weill Cornell Chelsea CRS New York, New York, United States, 10010 7803 Weill Cornell Upton CRS New York, New York, United States, 10065 United States, Ohio 2401 Cincinnati CRS Cincinnati, Ohio, United States, 45267-0405 United States, Pennsylvania 6201 Penn Therapeutics CRS Philadelphia, Pennsylvania, United States, 19104 United States, Texas 31443 Trinity Health and Wellness Center CRS Dallas, Texas, United States, 75208 31473 Houston AIDS Research Team (HART) CRS Houston, Texas, United States, 77030 Collapse << |
| NCT02128217 | - | - | Completed | - | - |
| NCT02959359 | Hepatocellular Carcinoma | Phase 4 | Withdrawn(The supplies of stud... more >>y drug were halted by Gilead Sciences Ltd.) Collapse << | December 2022 | - |
| NCT03188276 | Chronic Hepatitis C | Early Phase 1 | Completed | - | - |
| NCT02591277 | - | - | Completed | - | - |
| NCT02657694 | - | - | Enrolling by invitation | June 30, 2018 | Australia, Tasmania ... more >> FixHepC Hobart, Tasmania, Australia, 7004 Collapse << |
| NCT02768961 | Hepatitis C | Phase 4 | Completed | - | Spain ... more >> Penitentiary "El Dueso". Cantabria. Spain Santoña, Cantabria, Spain, 39740 Collapse << |
| NCT01805882 | Hepatitis C, Chronic | Phase 2 | Completed | - | United States, District of Col... more >>umbia Unity Health Care, Inc./DC General Washington, D.C., District of Columbia, United States, 20002 Family Medical and Conseling Services Washington, D.C., District of Columbia, United States, 20020 United States, Maryland National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT02691728 | Chronic Hepatitis C | Phase 4 | Unknown | May 2017 | United States, California ... more >> Peter J. Ruane, MD, Inc. Los Angeles, California, United States, 90036 Collapse << |
| NCT01805882 | - | - | Completed | - | - |
| NCT02759861 | Genotype 1 Hepatitis C Virus | Phase 4 | Active, not recruiting | August 2020 | United States, Nebraska ... more >> University of Nebraska Omaha, Nebraska, United States, 680017 Collapse << |
| NCT03118674 | Porphyria Cutanea Tarda ... more >> Hepatitis C Collapse << | Phase 2 | Recruiting | August 30, 2022 | United States, Alabama ... more >> University of Alabama, Birmingham Recruiting Birmingham, Alabama, United States, 35294 Contact: Angelia Johnson 205-934-0498 angeliagjohnson@uabmc.edu Principal Investigator: Ashwani Singal, MD,MS United States, California University of California, San Francisco Recruiting San Francisco, California, United States, 94143 Contact: Yuvraaj Kapoor, MS 415-476-8405 yuvraaj.kapoor@ucsf.edu Principal Investigator: D. Montgomery Bissell, MD United States, New York Icahn School of Medicine at Mount Sinai Recruiting New York, New York, United States, 10029 Contact: Karli Hedstrom, MPH 212-659-1450 karli.hedstrom@mssm.edu Contact: Tanushree Laud 212-659-1418 tanushree.laud@mssm.edu Principal Investigator: Behnam Saberi, MD United States, North Carolina Wake Forest University Health Sciences Recruiting Winston-Salem, North Carolina, United States, 27157 Contact: Dee Faust 336-713-1442 delannin@wakehealth.edu Principal Investigator: Herbert L Bonkovsky, MD United States, Texas University of Texas Medical Branch Recruiting Galveston, Texas, United States, 77555 Contact: Csilla Hallberg, MD 409-772-6287 challberg@utmb.edu Principal Investigator: Kar Anderson, MD United States, Utah University of Utah Recruiting Salt Lake City, Utah, United States, 84132 Contact: Sharada Dixit 801-587-7525 sharada.dixit@hsc.utah.edu Principal Investigator: John Phillips, PhD Collapse << |
| NCT02339038 | - | - | Completed | - | - |
| NCT02760355 | Insulin Resistance | Not Applicable | Active, not recruiting | June 2018 | Switzerland ... more >> Division of Gastroenterology and hepatology, University Hospital Geneva, GE, Switzerland, 1211 Collapse << |
| NCT02717949 | Liver Disease | Phase 4 | Terminated(failure to recruit) | - | United States, New York ... more >> Cornell Medical Center New York, New York, United States, 10065 Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 United States, Texas UT Southwestern Medical Center Dallas, Texas, United States, 75390 Collapse << |
| NCT02858180 | Hepatitis C, Chronic ... more >> Heart Failure Pulmonary Disease, Chronic Obstructive Lung Diseases, Interstitial Collapse << | Phase 4 | Recruiting | December 2018 | United States, Michigan ... more >> Henry Ford Health System Recruiting Detroit, Michigan, United States, 48377 Contact: Julia Forbes 313-916-8423 JFORBES1@hfhs.org Principal Investigator: Gordon Stuart, MD United States, New York Columbia University Medical Center Recruiting New York, New York, United States, 10032 Contact: Patricia Harren 212-305-1877 ph176@columbia.edu Principal Investigator: Elizabeth Verna, MD United States, North Carolina Duke University Medical Center - Dept of Gastroenterology Recruiting Durham, North Carolina, United States, 27705 Contact: Tameka Street Tameka.street@duke.edu Principal Investigator: Julius Wilder, MD United States, Washington Harborview Medical Center Recruiting Seattle, Washington, United States, 98104 Contact: Lee McKoin 206-744-2341 mckoin@medicine.washington.edu Principal Investigator: Charles Landis, MD Collapse << |
| NCT02660905 | Human Immunodeficiency Virus ... more >> Hepatitis C, Chronic Collapse << | Phase 3 | Active, not recruiting | December 2017 | Canada, Ontario ... more >> The Ottawa Hospital, General Campus Ottawa, Ontario, Canada Canada, Quebec The Research Institute of the McGill University Health Centre Montreal, Quebec, Canada, H4A 3J1 Collapse << |
| NCT01958281 | HCV Infection | Phase 2 | Completed | - | United States, California ... more >> San Francisco, California, United States, 94115 United States, Florida Miami, Florida, United States, 33134 United States, Illinois Chicago, Illinois, United States, 60611 United States, Michigan Detroit, Michigan, United States, 48202 United States, New York Rochester, New York, United States, 14642 United States, Texas San Antonio, Texas, United States, 78215 United States, Washington Seattle, Washington, United States, 98104 New Zealand Grafton, Auckland, New Zealand, 1142 Christchurch, New Zealand, 8011 Puerto Rico San Juan, Puerto Rico, 00927 Collapse << |
| NCT02339038 | HCV HIV | Phase 4 | Completed | - | United States, District of Col... more >>umbia Unity Health Care, Inc./DC General Washington, District of Columbia, United States, 20002 Family Medical and Conseling Services Washington, District of Columbia, United States, 20020 Collapse << |
| NCT02650024 | Hepatitis C H... more >>uman Immunodeficiency Virus Collapse << | Phase 4 | Recruiting | July 2020 | United States, California ... more >> Ucsd Hnrp Recruiting San Diego, California, United States, 92103 Contact: Melanie Crescini, B.S. 619-543-5016 mscrescini@ucsd.edu Collapse << |
| NCT02707601 | HIV-1 Infection ... more >> HCV Infection Collapse << | Phase 3 | Completed | - | - |
| NCT01193478 | HCV Infection | Phase 1 | Completed | - | United States, California ... more >> Anaheim, California, United States, 92801 Cypress, California, United States, 90630 National City, California, United States, 91950 United States, District of Columbia Washington, District of Columbia, United States, 20010 United States, Florida Deland, Florida, United States, 32720 Miami, Florida, United States, 33169 Orlando, Florida, United States, 32809 United States, Missouri St. Louis, Missouri, United States, 63104 United States, Oregon Portland, Oregon, United States, 97239 United States, Pennsylvania Philadelphia, Pennsylvania, United States, 19139 United States, Texas Houston, Texas, United States, 77030 San Antonio, Texas, United States, 78215 United States, Washington Tacoma, Washington, United States, 98418 Collapse << |
| NCT01958281 | - | - | Completed | - | - |
| NCT02707601 | - | - | Completed | - | - |
| NCT01353248 | Hepatitis C, Chronic | Phase 2 | Completed | - | - |
| NCT02576314 | Chronic Hepatitis C Infection | Phase 3 | Completed | - | China, Beijing ... more >> Liver Fibrosis Diagnosis and Treatment Centre, 302 Hospital Beijing, Beijing, China, 100039 China, Hong Kong Humanity and Health GI and Liver Centre Hong Kong, Hong Kong, China, 00852 Collapse << |
| NCT02309918 | Acute Hepatitis C | Phase 2 | Completed | - | Germany ... more >> • Charite, Universitätsmedizin Berlin, Campus Virchow-Klinikum, Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie Berlin, Germany, 13353 Universitätsklinikum Bonn, Medizinische Klinik und Poliklinik I Bonn, Germany, 53105 Medizinisches Versorgungszentrum Düsseldorf, Germany, 40237 • Universitätsklinikum Essen, Klinik für Gastroenterologie und Hepatologie Essen, Germany, 45122 Universitätsklinikum Frankfurt, Medizinische Klinik 1 Frankfurt, Germany, 60590 Universitätsklinikum Freiburg, Klinik für Innere Medizin II, Gastroenterologie, Hepatologie, Endokrinologie und Infektiologie Freiburg, Germany, 79106 Ifi, Institut für Interdisziplinäre Medizin Hamburg, Germany, 20099 Universitätsklinikum Hamburg-Eppendorf, Medizinische Klinik und Poliklinik Hamburg, Germany, 20246 Medizinische Hochschule Hannover, Klinik für Gastroenterologie, Hepatologie und Endokrinologie Hannover, Germany, 30625 Universitätsklinikum Heidelberg, Gastroenterologie, Infektionen, Vergiftungen Heidelberg, Germany, 69120 Gastroenterologische Gemeinschaftspraxis Herne Herne, Germany, 44623 Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes, Klinik für Innere Medizin II - Gastroenterologie und Endokrinologie Homburg, Germany, 66421 Universitätsklinikum Schleswig-Holstein, Klinik für Innere Medizin 1, Gastroenterologie, Hepatologie, Ernährungs- und Altersmedizin Kiel, Germany, 24105 Universitätsklinikum Leipzig, Klinik und Poliklinik für Gastroenterologie und Rheumatologie Leipzig, Germany, 4103 Universitätsmedizin der Johannes Gutenberg-Universität Mainz, I. Medizinische Klinik und Poliklinik Mainz, Germany, 55131 Oberberg City München München, Germany, 80331 Klinikum rechts der Isar der TU-München, II. Medizinische Klinik und Poliklinik (Gastroenterologie) München, Germany, 81675 Medizinisches Versorgungszentrum Offenburg GmbH, St. Josefklinik, Ambulante Gastroenterologie Offenburg, Germany, 77654 Universitätsklinikum Tübingen, Innere Medizin I, Hepatologie, Gastroenterologie, Infektiologie Tübingen, Germany, 72076 Universitätsklinikum Würzburg,Medizinische Klinik und Poliklinik II, Zentrum Innere Medizin Würzburg, Germany, 97080 Collapse << |
| NCT02588287 | Hepatitis C and HIV Coinfectio... more >>n Collapse << | Not Applicable | Active, not recruiting | December 2018 | United States, Colorado ... more >> University of Colorado Hospital Aurora, Colorado, United States, 80045 Collapse << |
| NCT02503735 | Hepatitis C C... more >>hronic Kidney Disease Collapse << | Not Applicable | Active, not recruiting | December 2019 | United States, Massachusetts ... more >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Collapse << |
| NCT01878799 | - | - | Completed | - | - |
| NCT01878799 | Hepatitis C H... more >>IV Collapse << | Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT02964091 | Chronic Hepatitis C | Phase 4 | Completed | - | Rwanda ... more >> Rwanda Military Hospital Kanombe, Kigali, Rwanda, 00000 Collapse << |
| NCT01371578 | Hepatitis C, Chronic | Phase 2 | Completed | - | - |
| NCT01701401 | Chronic Hepatitis C Virus | Phase 3 | Completed | - | - |
| NCT01356160 | Hepatitis C, Chronic | Phase 2 | Completed | - | - |
| NCT01435226 | Hepatitis C, Chronic | Phase 2 | Completed | - | - |
| NCT01701401 | - | - | Completed | - | - |
| NCT01975675 | Chronic HCV Infection | Phase 3 | Completed | - | Japan ... more >> Ichikawa, Chiba, Japan, 272-8516 Kurume, Fukuoka, Japan, 830-0011 Ogaki, Gifu, Japan, 503-0864 Sapporo, Hokkaido, Japan, 060-8648 Nishinomiya, Hyogo, Japan, 663-8501 Matsumoto, Nagano, Japan, 390-8621 Omura, Nagasaki, Japan, 856-8562 Suita, Osaka, Japan, 565-0871 Izunokuni, Shizuoka, Japan, 410-2295 Chiyoda-ku, Tokyo, Japan, 101-8643 Itabashi-ku, Tokyo, Japan, 173-8610 Musashino, Tokyo, Japan, 180-8610 Shinjuku, Tokyo, Japan, 162-8566 Kofu, Yamanashi, Japan, 400-0027 Akita, Japan, 010-0933 Chiba, Japan, 260-0856 Gifu, Japan, 500-8513 Okayama, Japan, 700-8558 Yamagata, Japan, 990-9585 Collapse << |
| NCT01434498 | Chronic Genotype 1a or 1b HCV ... more >>Infection Collapse << | Phase 2 | Completed | - | - |
| NCT02605304 | - | - | Terminated(The study experienc... more >>ed enrollment difficulties.) Collapse << | - | - |
| NCT02605304 | HIV-1 Infection ... more >> Hepatitis C Collapse << | Phase 2 | Terminated(The study experienc... more >>ed enrollment difficulties.) Collapse << | - | United States, California ... more >> Ucsf Aids Crs (801) San Francisco, California, United States, 94110 United States, New York 7804 Weill Cornell Chelsea CRS New York, New York, United States, 10010 Collapse << |
| NCT01384383 | Chronic Hepatitis C | Phase 2 | Terminated | - | - |
| NCT02480166 | PT-NANBH | Phase 4 | Completed | - | United States, California ... more >> Stanford University Medical Center Palo Alto, California, United States, 94304 San Jose Gastroenterology San Jose, California, United States, 95128 United States, Texas Liver and Digestive Consultants Houston, Texas, United States, 77072 Digestive Health Associates Plano, Texas, United States, 75093 Collapse << |
| NCT02480166 | - | - | Completed | - | - |
| NCT02249182 | Hepatitis C Virus Infection | Phase 2 | Completed | - | - |
| NCT02120300 | - | - | Completed | - | - |
| NCT03032666 | Thalassemia H... more >>epatitis C Collapse << | Phase 4 | Completed | - | Lebanon ... more >> American University of Beirut Medical Center Beirut, Lebanon Collapse << |
| NCT02120300 | Chronic HCV Infection | Phase 2 | Completed | - | United States, California ... more >> Sacramento, California, United States, 95817 San Diego, California, United States, 92103-8651 San Francisco, California, United States, 94143 United States, District of Columbia Washington, District of Columbia, United States, 20007 United States, Georgia Atlanta, Georgia, United States, 30308 United States, Massachusetts Boston, Massachusetts, United States, 02114 Boston, Massachusetts, United States, 02115 United States, Minnesota Minneapolis, Minnesota, United States, 55407 United States, New Jersey Newark, New Jersey, United States, 07112 United States, New York New York, New York, United States, 10029 Rochester, New York, United States, 14621 United States, North Carolina Chapel Hill, North Carolina, United States, 27599-7584 United States, Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Collapse << |
| NCT01965535 | HCV Infection | Phase 2 | Completed | - | France ... more >> Clermont Ferrand, France, 63003 Clichy, France, 92110 Creteil, France, 94000 Grenoble, France, 38043 Lille, France, 57037 Limoges, France, 87042 Lyon, France, 69317 Marseille, France, 13285 Montpelier, France, 34295 Nancy, France, 54500 Nice, France, 06202 Paris, France, 75012 Paris, France, 75013 Paris, France, 75014 Paris, France, 75020 Pessac, France, 33604 Rennes, France, 35033 Strasbourg, France, 67091 Toulouse, France, 31059 Collapse << |
| NCT02631772 | Hepatitis C | Phase 4 | Completed | - | United States, District of Col... more >>umbia Medstar Georgetown University Hospital Washington, District of Columbia, United States, 20057 United States, Ohio University Hospitals Cleveland Medical Center Cleveland, Ohio, United States, 44106 United States, Pennsylvania University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 United States, South Carolina Medical University of South Carolina Charleston, South Carolina, United States, 29425 Collapse << |
| NCT02738333 | Hepatitis C Virus Infection | Phase 3 | Completed | - | Japan ... more >> Bunkyo, Japan Chiba, Japan Chuo City, Japan Ehime, Japan Fukuoka, Japan Fukuyama, Japan Gifu, Japan Ibaragi, Japan Ikeda, Japan Iruma-gun, Japan Itabashi, Japan Izunokuni, Japan Kagoshima, Japan Kashihara, Japan Kitakyushu, Japan Kumamoto, Japan Kyoto, Japan Maebashi, Japan Matsumoto, Japan Morioka, Japan Musashino, Japan Nagasaki, Japan Nagoya, Japan Nishinomiya, Japan Ogaki City, Japan Okayama, Japan Omura, Japan Osaka, Japan Sagamihara, Japan Saga, Japan Sapporo, Japan Sendai, Japan Suita, Japan Takamatsu, Japan Ube, Japan Yamagata, Japan Yufu, Japan Collapse << |
| NCT01965535 | - | - | Completed | - | - |
| NCT02226549 | Hepatitis C Virus Infection | Phase 2 | Completed | - | United States, Texas ... more >> San Antonio, Texas, United States Collapse << |
| NCT02226549 | - | - | Completed | - | - |
| NCT01975675 | - | - | Completed | - | - |
| NCT01938430 | Chronic HCV Infection | Phase 2 | Completed | - | - |
| NCT02010255 | Chronic HCV Infection | Phase 2 | Completed | - | - |
| NCT02738333 | - | - | Completed | - | - |
| NCT01987453 | HCV Infection | Phase 2 | Completed | - | - |
| NCT02073656 | Hepatitis C Virus ... more >> HIV Collapse << | Phase 3 | Completed | - | - |
| NCT01938430 | - | - | Completed | - | - |
| NCT02219685 | Hepatitis C Virus Infection | Phase 2 | Completed | - | United States, Massachusetts ... more >> Boston, Massachusetts, United States Collapse << |
| NCT02073656 | - | - | Completed | - | - |
| NCT02010255 | - | - | Completed | - | - |
| NCT01851330 | Chronic Hepatitis C Virus | Phase 3 | Completed | - | - |
| NCT02219685 | - | - | Completed | - | - |
| NCT01851330 | - | - | Completed | - | - |
| NCT01987453 | - | - | Completed | - | - |
| NCT03126370 | Hepatitis C H... more >>IV Coinfection Collapse << | Phase 4 | Recruiting | August 31, 2019 | United States, Colorado ... more >> University of Colorado Hospital Recruiting Aurora, Colorado, United States, 80045 Contact: Jennifer J Kiser, PharmD 303-724-6131 jennifer.kiser@ucdenver.edu Contact: Kristina M Brooks, PharmD 303-724-0395 kristina.brooks@ucdenver.edu Collapse << |
| NCT02350569 | Hepatitis C Virus Infection | Phase 2 | Completed | - | United States, California ... more >> San Francisco, California, United States United States, Illinois Chicago, Illinois, United States United States, Louisiana New Orleans, Louisiana, United States United States, Michigan Detroit, Michigan, United States United States, New York New York, New York, United States United States, Texas Dallas, Texas, United States Collapse << |
| NCT02350569 | - | - | Completed | - | - |
| NCT02457611 | Hepatitis C Infection With HIV... more >> Co-Infection Collapse << | Phase 2 | Completed | - | Germany ... more >> Berlin, Germany Bonn, Germany Frankfurt am Main, Germany United Kingdom London, United Kingdom Collapse << |
| NCT02081079 | Chronic Genotype 4 HCV ... more >> Chronic Genotype 5 HCV Collapse << | Phase 2 | Completed | - | France ... more >> Clermont Ferrand, France, 63003 Clichy, France, 92110 Limoges, France, 87042 Toulouse, France, 31059 Villejuif, France, 94800 Collapse << |
| NCT02457611 | - | - | Completed | - | - |
| NCT02251717 | - | - | Completed | - | - |
| NCT02251717 | Hepatitis C Virus Infection | Phase 2 | Completed | - | Austria ... more >> Wien, Austria France Marseille, France Paris, France Germany Hannover, Germany Italy Milan, Italy Collapse << |
| NCT01768286 | - | - | Completed | - | - |
| NCT02597166 | Hepatitis C, Chronic ... more >> Cirrhosis, Decompensated Collapse << | Phase 3 | Completed | - | Canada, Ontario ... more >> University Health Network - Toronto General Hospital Toronto, Ontario, Canada, M5G 2C4 Collapse << |
| NCT01768286 | Chronic Hepatitis C Virus | Phase 3 | Completed | - | - |
| NCT02868242 | Hepatitis C Virus Infection | Phase 2 | Active, not recruiting | February 2019 | Egypt ... more >> National Cancer Institute, Cairo University Cairo, Egypt Collapse << |
| NCT02081079 | - | - | Completed | - | - |
| NCT02301936 | Hepatitis C Virus Infection | Phase 2 | Completed | - | United States, Maryland ... more >> Lutherville, Maryland, United States Collapse << |
| NCT02613871 | Hepatitis C Virus Infection | Phase 3 | Completed | - | Taiwan ... more >> Changhua, Taiwan Chiayi City, Taiwan Kaohsiung City, Taiwan Kaohsiung, Taiwan Keelung, Taiwan Taichung, Taiwan Tainan City, Taiwan Tainan, Taiwan Taipei City, Taiwan Taipei, Taiwan Taoyuan, Taiwan Collapse << |
| NCT02021656 | Chronic HCV Infection | Phase 3 | Completed | - | - |
| NCT02413593 | Hepatitis C Virus Infection | Phase 2 | Completed | - | Canada, Alberta ... more >> Calgary, Alberta, Canada, T2N 4Z6 Edmonton, Alberta, Canada, T5H 4B9 Edmonton, Alberta, Canada, T6G 2B7 Canada, British Columbia Vancouver, British Columbia, Canada, V5Z 1H2 Vancouver, British Columbia, Canada, V5Z 1M9 Vancouver, British Columbia, Canada, V6Z 2K5 Canada, Ontario Brampton, Ontario, Canada, L6R 3J7 London, Ontario, Canada, N6A 5A5 Ottawa, Ontario, Canada, K1H 8L6 Toronto, Ontario, Canada, M5T 2S8 Toronto, Ontario, Canada, M6H 3M1 Vaughan, Ontario, Canada, L4L 4Y7 Canada, Quebec Montreal, Quebec, Canada, H2L 4P9 Montreal, Quebec, Canada, H2X 0A9 Canada Quebec, Canada, G1V 4G2 Collapse << |
| NCT02301936 | - | - | Completed | - | - |
| NCT02413593 | - | - | Completed | - | - |
| NCT03036839 | Chronic Hepatitis c | Phase 2 | Active, not recruiting | February 2019 | United States, Massachusetts ... more >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 United States, Michigan Henry Ford Health System Detroit, Michigan, United States, 48202 United States, New York James J. Peters Veterans Administration Medical Center Bronx, New York, United States, 10468 United States, Texas Methodist Healthcare Dallas - The Liver Institute Dallas, Texas, United States, 75203 Texas Liver Institute/American Research Corporation San Antonio, Texas, United States, 78215 United States, Washington University of Washington Seattle, Washington, United States, 98104 Belgium CUB Hopital Erasme Brussels, Belgium, 1070 Cliniques Universitaires UCL Saint-Luc Brussels, Belgium, 1200 Germany JWG-Universität Frankfurt Frankfurt, Germany, 60590 Universitatsklinikum Hamburg-Eppendorf Hamburg, Germany, 20246 Ifi Studien und Projekt GmbH Hamburg, Germany, 20251 University of Leipzig Leipzig, Germany, 04109 Italy IRCCS Ospedale Casa Sollievo Della Soferrenza San Giovanni Rotondo, Foggia, Italy, 71013 Ospedale Santa Maria Annunziata Antella, Italy, 50011 Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan, Italy, 20122 Azienda Ospedaliera Città della Salute e della Scienza di Torino Torino, Italy, 10126 Taiwan Changhua Christian Hospital Changhua, Taiwan, 500 Kaohsiung Medical University Hospital Kaohsiung, Taiwan, 807 Kaohsiung Chang Gung Memorial Hospital Kaohsiung, Taiwan, 83301 China Medical University Hospital Taichung, Taiwan, 40447 National Taiwan University Hospital Taipei, Taiwan, 10002 Collapse << |
| NCT02487030 | - | - | Completed | - | - |
| NCT02487030 | Hepatitis C Virus Infection | Phase 3 | Completed | - | Egypt ... more >> Cairo, Egypt, 11559 Cairo, Egypt, 11796 Mansourah, Egypt Shibin Al Kawm, Egypt Collapse << |
| NCT02472886 | Hepatitis C Virus Infection | Phase 3 | Completed | - | Estonia ... more >> Tallinn, Estonia, 10167 Tartu, Estonia, 51014 Russian Federation Ekaterinburg, Russian Federation, 620102 Krasnoyarsk, Russian Federation, 660049 Moscow, Russian Federation, 105275 Moscow, Russian Federation, 107014 Moscow, Russian Federation, 111123 Moscow, Russian Federation, 115446 Moscow, Russian Federation, 117593 Moscow, Russian Federation, 119435 Moscow, Russian Federation, 119991 Moscow, Russian Federation, 125367 Moscow, Russian Federation, 127015 Moscow, Russian Federation, 129090 Moscow, Russian Federation, 129110 Samara, Russian Federation, 443063 St. Petersburg, Russian Federation, 190103 St.petersburg, Russian Federation, 194044 Stavropol, Russian Federation, 355017 Tyumen, Russian Federation, 625026 Collapse << |
| NCT01984294 | - | - | Completed | - | - |
| NCT03005210 | Healthy | Phase 1 | Completed | - | Egypt ... more >> Genuine Research Center GRC Cairo, Egypt, 11757 Collapse << |
| NCT02472886 | - | - | Completed | - | - |
| NCT02600351 | Hepatitis C Virus Infection | Phase 3 | Terminated(Due to lack of feas... more >>ibility of enrolling participants, the study was terminated early.) Collapse << | - | - |
| NCT02347345 | Hepatitis C | Phase 4 | Completed | - | United States, New York ... more >> Rockefeller University Hospital New York, New York, United States, 10021 Collapse << |
| NCT01984294 | Chronic HCV Infection | Phase 2 | Completed | - | United States, Texas ... more >> San Antonio, Texas, United States, 78215 Collapse << |
| NCT02600351 | - | - | Terminated(Due to lack of feas... more >>ibility of enrolling participants, the study was terminated early.) Collapse << | - | - |
| NCT03721627 | Gaucher Disease ... more >> HCV Collapse << | Phase 4 | Recruiting | October 2019 | Egypt ... more >> Mansoura University Children Hospital, Ped Gastroenteroloy and Hepatology Unit Recruiting Mansoura, Dakahliya, Egypt, 35516 Contact: Ahmed Megahed, MD +201224642996 megahed732000@gmail.com Collapse << |
| NCT02405013 | Hepatitis C H... more >>IV Infection Collapse << | Phase 2 | Completed | - | Cameroon ... more >> Clinique de la Cathédrale Yaoundé, Cameroon Côte D'Ivoire Centre de suivi des donneurs de sang Abidjan, Côte D'Ivoire CHU de Youpougon - Service de Gastro-entéro-hépatologie Abidjan, Côte D'Ivoire Senegal CHU Fann, Service des Maladies Infectieuses Dakar, Senegal Collapse << |
| NCT02480387 | Treatment of Hepatitis C | Phase 2 | Completed | - | United States, California ... more >> Peter J. Ruane, MD, Inc. Los Angeles, California, United States, 90036 Collapse << |
| NCT01924949 | - | - | Completed | - | - |
| NCT03061032 | Hepatitis C | Phase 3 | Not yet recruiting | July 2019 | - |
| NCT02683005 | Hepatitis C P... more >>regnancy Collapse << | Phase 1 | Active, not recruiting | February 2020 | United States, Pennsylvania ... more >> Magee Womens Hospital Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT02613871 | - | - | Completed | - | - |
| NCT01924949 | Hepatitis C | Phase 2 | Completed | - | United States, Massachusetts ... more >> Boston, Massachusetts, United States Collapse << |
| NCT02478229 | Hepatitis C Viral Infection | Phase 3 | Terminated(difficulty recruiti... more >>ng patients) Collapse << | - | Canada, Ontario ... more >> University Health Network Toronto, Ontario, Canada, M5G 2N2 Collapse << |
| NCT02421211 | - | - | Completed | - | - |
| NCT03743727 | Hepatitis C Genotype 4 | Phase 4 | Recruiting | June 30, 2019 | Egypt ... more >> Professor Yassin Abdel Ghaffar Charity Center for Liver Disease and Research Recruiting Nasr City, Cairo, Egypt Contact: Mamdouh A. Ahmed 02-01221707770 dr.yassinabdelghaffar@gmail.com Collapse << |
| NCT03639207 | - | - | Not yet recruiting | September 30, 2026 | United States, California ... more >> Kaiser Permanente Northern California Not yet recruiting Oakland, California, United States, 94612 Contact: David Witt, M.D. 415-444-2940 david.j.witt@kp.org Collapse << |
| NCT02421211 | Hepatitis C, Chronic | Phase 2 | Completed | - | Belgium ... more >> Antwerpen, Belgium Brussel, Belgium Gent, Belgium Leuven, Belgium Canada, Ontario Toronto, Ontario, Canada Collapse << |
| NCT03343444 | Hepatitis C Virus Infection, R... more >>esponse to Therapy of Collapse << | Phase 3 | Enrolling by invitation | May 31, 2019 | Egypt ... more >> Egyptian Liver Hospital Mansourah, Dakahlia, Egypt, 36681 Collapse << |
| NCT02638233 | Chronic Hepatitis C | Phase 4 | Unknown | September 2016 | Austria ... more >> Wilhelminenspital Recruiting Vienna, Austria, 1160 Contact: Michael Gschwantler, Prof. MD 0043 1 491502401 michael.gschwantler@wienkav.at Contact: Johann Haltmayer, MD, HCM 0043 1 4000 53 603 hans.haltmayer@sd-wien.at Collapse << |
| NCT03764345 | Hepatitis C, Chronic ... more >> Children, Only Collapse << | Not Applicable | Completed | - | Egypt ... more >> Pediatric Hepatology, Gastroenterology and Nutrition Department, National Liver Institute, Menoufia University Shebin El-Koom, Menofiya, Egypt, 32511 Collapse << |
| NCT03261349 | Indolent Lymphoma | Phase 2 | Not yet recruiting | August 15, 2021 | - |
| NCT02705534 | Hepatitis C C... more >>irrhosis Collapse << | Phase 3 | Completed | - | Iran, Islamic Republic of ... more >> Shariati Hospital Tehran, Iran, Islamic Republic of, 14117 Collapse << |
| NCT03279133 | Hematopoietic Stem Cell Transp... more >>lantation Collapse << | Phase 4 | Withdrawn(Unable to find eligi... more >>ble patients with untreated hepatitis C virus.) Collapse << | - | United States, California ... more >> City of Hope Duarte, California, United States, 91010 Kaiser Permanente Los Angeles Medical Center Los Angeles, California, United States, 90027 Collapse << |
| NCT03312023 | Hepatitis B | Phase 2 | Recruiting | November 2019 | United States, Maryland ... more >> Institute of Human Virology (IHV), University of Maryland Baltimore Recruiting Baltimore, Maryland, United States, 21201 Contact: Joel V Chua, MD 410-706-5704 Contact: Amy Nelson, BSN, MS 410-706-0100 anelson@ihv.umaryland.edu Collapse << |
| NCT02836925 | Indolent B-cell Lymphoma ... more >> Hepatitis C Collapse << | Phase 2 | Recruiting | May 2022 | Italy ... more >> A.O. Spedali Civili Recruiting Brescia, BS, Italy, 25100 Contact: Marina Motta, MD +39 0303996269 marina.motta@spedalicivili.brescia.it Principal Investigator: Marina Motta, MD Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Not yet recruiting Milano, MI, Italy, 20122 Contact: Luca Baldini, MD 0039 02 55033334 luca.baldini@unimi.it Principal Investigator: Luca Baldini Irccs Centro Di Riferimento Oncologico (Cro) Recruiting Aviano, Pordenone, Italy, 33801 Contact: Michele Spina mspina@cro.it Principal Investigator: Michele Spina, MD Ospedale San Bortolo Recruiting Vicenza, VI, Italy, 36100 Contact: Carlo Visco, MD +39 0444-753626/3518 carlovisco@hotmail.com;silvia.finotto@gmail.com Principal Investigator: Carlo Visco, MD Ospedale Policlinico G.B. Rossi (Borgo Roma) Di Verona Not yet recruiting Verona, VR, Italy, 37126 Principal Investigator: Dino Veneri, MD A.O. Universitaria Careggi Di Firenze Not yet recruiting Firenze, Italy, 50139 Contact: Luigi Rigacci Contact luigi.rigacci@unifi.it Principal Investigator: Luigi Rigacci, MD Sc Ematologia Ao Niguarda Ca' Granda Not yet recruiting Milano, Italy, 20162 Contact: Alessandra Tedeschi alessandra.tedeschi@ospedaleniguarda.it Ematologia e Trapianto IRCCS, Istituto Nazionale dei Tumori Recruiting Milano, Italy Principal Investigator: Anna Dodero, MD Ospedale San Raffaele Ematologia Recruiting Milano, Italy Principal Investigator: Andrés Ferreris, MD IRCCS Fondazione Pascale Not yet recruiting Napoli, Italy, 80131 Principal Investigator: Antonello Pinto, MD U.O. Ematologia AO di Padova Recruiting Padova, Italy Contact: Francesco Piazza francesco.piazza@unipd.it Principal Investigator: Francesco Piazza Policlinico P.Giaccone Not yet recruiting Palermo, Italy Principal Investigator: Emilio Iannitto, MD A.O. Universitaria Di Parma Recruiting Parma, Italy, 43126 Contact fre@ao.pr.it Principal Investigator: Francesca Re, MD Ematologia Policlinico San Matteo Recruiting Pavia, Italy, 27100 Contact: Luca Arcaini, M.D. 00390382503595 luca.arcaini@unipv.it Principal Investigator: Luca Arcaini, M.D. Ospedale Civile Piacenza Recruiting Piacenza, Italy Contact: Daniele Vallisa, MD d.vallisa@ausl.pc.it Principal Investigator: Daniele Vallisa Ematologia - Policlinico Umberto I Università Sapienza Recruiting Roma, Italy Contact: Alessandro Pulsoni pulsoni@bce.uniroma1.it Principal Investigator: Alessandro Pulsoni Dipartimento di Oncologia Medica ed Ematologia, Istituto Humanitas Recruiting Rozzano, Italy Contact: Armando Santoro, MD Principal Investigator: Armando Santoro, MD AOU Città della Salute e della Scienza di Torino Recruiting Torino, Italy, 10126 Contact: Lorella Orsucci, MD lorsucci@cittadellasalute.to.it Principal Investigator: Lorella Orsucci, MD A.O. Universitaria S. Maria Della Misericordia Di Udine Not yet recruiting Udine, Italy, 33100 Principal Investigator: Francesco Zaja, MD Ospedale di Circolo e Fondazione Macchi Recruiting Varese, Italy Principal Investigator: Michele Merli, MD Collapse << |
| NCT02125500 | Viral Hepatitis C ... more >> HIV Collapse << | Phase 2 | Completed | - | France ... more >> Centre de Méthodologie et de Gestion de Rennes Rennes, France Collapse << |
| 靶点 | Description | IC50 |
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