400-920-2911 sales@csnpharm.cn
您的位置 : 首页 / Cell Cycle / DHFR / Lometrexol hydrate
CAS No.: 1435784-14-7
Synonyms: DDATHF hydrate;Lometrexol;DDATHF
Lometrexol hydrate (DDATHF hydrate), an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol hydrate can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol hydrate has anticancer activity[1][2].
生物活性
实验方案
技术信息
CAS号 | 1435784-14-7 | 储存条件 |
|
|
分子式 | C21H27N5O7 | 运输 | 蓝冰 | |
分子量 | 461.47 | 别名 | DDATHF hydrate;Lometrexol;DDATHF;DATHF;LY 264618 hydrate;LY-264618 |
联系我们
官方电话:400-920-2911
二维码
微信公众号 CSN官网