CAS No.: 1082949-67-4
LY-2584702 Catalog No. CSN15762
Synonyms: LY-2584702;LYS-6K2
LY2584702 is an orally available inhibitor of p70S6K signaling and inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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400-920-2911
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01372085 Tumors Phase 1 Completed - Singapore ... more >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Singapore, Singapore Collapse << NCT01394003 Advanced Cancer Phase 1 Terminated(The pharmacokinetic... more >> properties of the molecule do not allow for further dose escalation or development.) Collapse << - United States, California ... more >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Santa Monica, California, United States United States, Texas For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. San Antonio, Texas, United States Collapse << NCT01115803 Metastases, Neoplasm ... more >> Carcinoma, Non-small Cell Lung Renal Cell Carcinoma Neuroendocrine Tumors Collapse << Phase 1 Terminated(Primary objective h... more >>as been met; safety and pharmacokinetics have been characterized.) Collapse << - United States, Illinois ... more >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Chicago, Illinois, United States, 60637 France For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Bordeaux, France, 33076 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Villejuif, France, 94805 Collapse << - 更多
- 参考文献
- [1] Tolcher A, Goldman J, et al. A phase I trial of LY2584702 tosylate, a p70 S6 kinase inhibitor, in patients with advanced solid tumours. Eur J Cancer. 2014 Mar;50(5):867-75.
- [2] Hollebecque A, Houede N, et al. A phase Ib trial of LY2584702 tosylate, a p70 S6 inhibitor, in combination with erlotinib or everolimus in patients with solid tumours. Eur J Cancer. 2014 Mar;50(5):876-84.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1082949-67-4 | 储存条件 |
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| 分子式 | C21H19F4N7 | 运输 | 蓝冰 | |||||||
| 分子量 | 445.42 | 别名 | LY-2584702;LYS-6K2 | |||||||
| 溶解度 |
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动物实验配方 |
