||CsnPharm

CAS No.: 52665-74-4

Manumycin A/手霉素A Catalog No. CSN20562

Synonyms: NSC 622141;UCF 1C;手霉素A

Manumycin A is an antibiotic that acts as a potent and selective farnesyltransferase (FTase) inhibitor with anti-tumor activity. It inhibits rat brain FTase with a Ki value of 1.2 µM, thereby preventing Ras activation which requires farnesylation at the C-terminus for membrane attachment.

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

描述Manumycin A is an antibiotic that acts as a potent and selective farnesyltransferase (FTase) inhibitor with anti-tumor activity. It inhibits rat brain FTase with a Ki value of 1.2 µM, thereby preventing Ras activation which requires farnesylation at the C-terminus for membrane attachment.
参考文献

[1] Bernier M, Kwon YK, et al. Binding of manumycin A inhibits IkappaB kinase beta activity. J Biol Chem. 2006 Feb 3;281(5):2551-61.
[2] She M, Pan I, et al. Enhancement of manumycin A-induced apoptosis by methoxyamine in myeloid leukemia cells. Leukemia. 2005 Apr;19(4):595-602.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.8161 mL
- 9.0803 mL
- 18.1606 mL
- 5 mM
- 0.3632 mL
- 1.8161 mL
- 3.6321 mL
- 10 mM
- 0.1816 mL
- 0.9080 mL
- 1.8161 mL

技术信息

CAS号	52665-74-4	储存条件	粉末液体 -20°C:3-6 月 -80°C:12月
分子式	C31H38N2O7	运输	蓝冰
分子量	550.64	别名	NSC 622141;UCF 1C;手霉素A

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

Manumycin A/手霉素A Catalog No. CSN20562

靶点选择性

请登录您的专属账户

确认信息