CAS No.: 14957-38-1
Marmin Catalog No. CSN14575
Marmin, a natural product isolated and purified from the herbs of Citrus maxima with potent anti-ulcer, antibacterial, fungicidal, and algicidal properties, can inhibit contraction of the guinea-pig tracheal smooth muscle, especially by interfering histamine receptor, inhibiting the histamine release from mast, inhibiting intracellular Ca2+ release from the intracellular store and the Ca2+ influx through voltage-dependent Ca2+ channels, is potential to develop as antihistamine agents, especially as histamine H1 receptor antagonists by interacting with amino acid residues, Asp107, Lys179, Lys191, Asn198, and Trp428 of histamine H1 receptor, shows a cell-growth inhibitory effect against L1210 and K562 in vitro.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Nugroho AE, Anas Y, et al. Effects of marmin, a compound isolated from Aegle marmelos Correa, on contraction of the guinea pig-isolated trachea. Pak J Pharm Sci. 2011 Oct;24(4):427-33.
- [2] Takase H, Yamamoto K, et al. Pharmacological profile of gastric mucosal protection by marmin and nobiletin from a traditional herbal medicine, Aurantii fructus immaturus. Jpn J Pharmacol. 1994 Sep;66(1):139-47.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 14957-38-1 | 储存条件 |
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| 分子式 | C19H24O5 | 运输 | 蓝冰 | |
| 分子量 | 332.39 | 别名 |
