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CAS No.: 103909-75-7

Maxacalcitol/马沙骨化醇 Catalog No. CSN13764

Synonyms: 22-Oxacalcitriol;Maxacalcitrol;Maxacalcitriol

Maxacalcitol is non-calcemic vitamin D3 analog and ligand of VDR-like receptors.

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描述Maxacalcitol is non-calcemic vitamin D3 analog and ligand of VDR-like receptors.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT00828347	Secondary Hyperparathyroidism	Not Applicable	Completed	-	Japan ... more >> Kumamoto University Hospital Kumamoto, Japan, 860-8556 Collapse <<
NCT00990704	Secondary Hyperparathyroidism ... more >> Hemodialysis Collapse <<	Phase 2	Completed	-	Japan ... more >> Site Ref # / Investigator 53794 Anjo, Japan Site Ref # / Investigator 53787 Chiba, Japan Site Ref # / Investigator 53786 Kumagaya, Japan Site Ref # / Investigator 53792 Matsumoto, Japan Site Ref # / Investigator 53784 Mito, Japan Site Ref # / Investigator 53796 Nagasaki, Japan Site Ref # / Investigator 53795 Osaka, Japan Site Ref # / Investigator 21561 Sapporo, Japan Site Ref # / Investigator 53789 Tokyo, Japan Site Ref # / Investigator 53790 Tokyo, Japan Site Ref # / Investigator 53793 Toyohashi, Japan Site Ref # / Investigator 53785 Tsuchiura, Japan Site Ref # / Investigator 53788 Yachiyo, Japan Site Ref # / Investigator 53791 Yokosuka, Japan Collapse <<
NCT00990704	-	-	Completed	-	-

更多
参考文献

[1] Inoue K, Matsui I, et al. Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3. Lab Invest. 2012 Dec;92(12):1686-97.
[2] Karashima T, Hashikawa K, et al. Successful treatment of Bowen's disease with topical maxacalcitol. Acta Derm Venereol. 2012 Nov;92(6):660-1.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.3889 mL
- 11.9443 mL
- 23.8886 mL
- 5 mM
- 0.4778 mL
- 2.3889 mL
- 4.7777 mL
- 10 mM
- 0.2389 mL
- 1.1944 mL
- 2.3889 mL

技术信息

CAS号	103909-75-7		储存条件	粉末 Sealed in dry,Store in freezer, under -20°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C26H42O4		运输	蓝冰
分子量	418.61		别名	22-Oxacalcitriol;Maxacalcitrol;Maxacalcitriol;MC 1275;OCT;Prezios;Sch 209579;alpha,25-Dihydroxy-22-oxavitamin D3;22-Oxa-1,25-dihydroxyvitamin D3;马沙骨化醇

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT00828347	Secondary Hyperparathyroidism	Not Applicable	Completed	-	Japan ... more >> Kumamoto University Hospital Kumamoto, Japan, 860-8556 Collapse <<
NCT00990704	Secondary Hyperparathyroidism ... more >> Hemodialysis Collapse <<	Phase 2	Completed	-	Japan ... more >> Site Ref # / Investigator 53794 Anjo, Japan Site Ref # / Investigator 53787 Chiba, Japan Site Ref # / Investigator 53786 Kumagaya, Japan Site Ref # / Investigator 53792 Matsumoto, Japan Site Ref # / Investigator 53784 Mito, Japan Site Ref # / Investigator 53796 Nagasaki, Japan Site Ref # / Investigator 53795 Osaka, Japan Site Ref # / Investigator 21561 Sapporo, Japan Site Ref # / Investigator 53789 Tokyo, Japan Site Ref # / Investigator 53790 Tokyo, Japan Site Ref # / Investigator 53793 Toyohashi, Japan Site Ref # / Investigator 53785 Tsuchiura, Japan Site Ref # / Investigator 53788 Yachiyo, Japan Site Ref # / Investigator 53791 Yokosuka, Japan Collapse <<
NCT00990704	-	-	Completed	-	-
NCT00828347	-	-	Completed	-	-
NCT00667576	-	-	Completed	-	-
NCT01341782	Secondary Hyperparathyroidism ... more >> Hemodialysis Collapse <<	Phase 3	Completed	-	Japan ... more >> Site Reference ID/Investigator# 53485 Aichi, Japan Site Reference ID/Investigator# 51571 Chiba, Japan Site Reference ID/Investigator# 52963 Chiba, Japan Site Reference ID/Investigator# 52966 Chiba, Japan Site Reference ID/Investigator# 51578 Gifu, Japan Site Reference ID/Investigator# 52965 Gunma, Japan Site Reference ID/Investigator# 53782 Hadano-City, Japan Site Reference ID/Investigator# 57483 Himeji-City, Japan Site Reference ID/Investigator# 57487 Hokkaido, Japan Site Reference ID/Investigator# 53484 Hyogo, Japan Site Reference ID/Investigator# 54385 Ibaraki, Japan Site Reference ID/Investigator# 51581 Kagawa, Japan Site Reference ID/Investigator# 59164 Kagoshima, Japan Site Reference ID/Investigator# 51574 Kanagawa, Japan Site Reference ID/Investigator# 51575 Kanagawa, Japan Site Reference ID/Investigator# 52751 Kodaira, Japan Site Reference ID/Investigator# 62025 Koga, Japan Site Reference ID/Investigator# 54384 Matsumoto, Japan Site Reference ID/Investigator# 52745 Midori, Japan Site Reference ID/Investigator# 51569 Mito, Japan Site Reference ID/Investigator# 52964 Nagano, Japan Site Reference ID/Investigator# 53483 Nagano, Japan Site Reference ID/Investigator# 51582 Nagasaki, Japan Site Reference ID/Investigator# 54388 Nagoya, Japan Site Reference ID/Investigator# 51576 Niigata, Japan Site Reference ID/Investigator# 51577 Niigata, Japan Site Reference ID/Investigator# 51580 Osaka, Japan Site Reference ID/Investigator# 52747 Osaka, Japan Site Reference ID/Investigator# 52748 Osaka, Japan Site Reference ID/Investigator# 52750 Osaka, Japan Site Reference ID/Investigator# 51570 Saitama, Japan Site Reference ID/Investigator# 54387 Sakai, Japan Site Reference ID/Investigator# 52746 Sapporo, Japan Site Reference ID/Investigator# 51579 Shizuoka, Japan Site Reference ID/Investigator# 62024 Takasaki, Japan Site Reference ID/Investigator# 51572 Tokyo, Japan Site Reference ID/Investigator# 52752 Tokyo, Japan Site Reference ID/Investigator# 53482 Tokyo, Japan Site Reference ID/Investigator# 59162 Tokyo, Japan Site Reference ID/Investigator# 59966 Tokyo, Japan Site Reference ID/Investigator# 53783 Tomakomai-shi, Japan Site Reference ID/Investigator# 54383 Toyama, Japan Site Reference ID/Investigator# 52749 Wakayama, Japan Site Reference ID/Investigator# 52962 Yachiyoshi, Japan Site Reference ID/Investigator# 59163 Yokohama-Shi, Japan Collapse <<
NCT00667576	Chronic Kidney Disease on Hemo... more >>dialysis Secondary Hyperparathyroidism Collapse <<	Phase 2	Completed	-	Japan ... more >> Tokyo, Metropolis, Japan Aichi, Prefecture, Japan Chiba, Prefecture, Japan Fukuoka, Prefecture, Japan Hokkaido, Prefecture, Japan Ibaragi, Prefecture, Japan Kanagawa, Prefecture, Japan Kumamoto, Prefecture, Japan Nagano, Prefecture, Japan Nagasaki, Prefecture, Japan Osaka, Prefecture, Japan Saitama, Prefecture, Japan Collapse <<
NCT01341782	-	-	Completed	-	-

总药量计算器 ✕

动物实验：给药剂量mg/kg 动物体重g 动物数量只每天给药次给药天

需要的总药量：mg

工作液计算器 ✕

动物实验：给药剂量mg/kg 动物体重g 给药体积μL

您需要配制的工作液浓度为：mg/mL

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