生物活性

• 描述Minaprine is a reversible inhibitor of MAO-A, a weak inhibitor acetylcholinesterase, and an antidepressant for treatment of depression.
• 临床研究

• NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
  NCT01938235	Myocardial Infarction	Phase 2	Unknown	January 2018	Canada, Alberta ... more >> Foothills Medical Centre Recruiting Calgary, Alberta, Canada, T2N 4Z6 Contact: Linda Manasterski    403-210-8548    linda.manasterski@albertahealthservices.ca    Principal Investigator: Faisal Al Qoofi, MD          Royal Alexandra Hospital Recruiting Edmonton, Alberta, Canada, T5H 3V9 Contact: Linda Kvill    780-735-5255    linda.kvill@albertahealthservices.ca    Principal Investigator: Neil Brass, MD          University of Alberta Hospital Recruiting Edmonton, Alberta, Canada, T6G 2B7 Contact: Suzanne Welsh    780-407-3572    suzanne.welsh@albertahealthservices.ca    Principal Investigator: Robert Welsh, MD          Canada, Ontario Hamilton Health Sciences - General Site Recruiting Hamilton, Ontario, Canada, L8L 2X2 Contact: Sonya Brons    905-527-4322 ext 44602    bronsson@hhsc.ca    Principal Investigator: Sanjit Jolly, MD          London Health Sciences Centre Recruiting London, Ontario, Canada, N6A 5A5 Contact: Mistre Alemayehu    519-685-8500 ext 35625    mistre.alemayehu@lhsc.on.ca    Principal Investigator: Shahar Lavi, MD          Southlake Regional Health Centre Recruiting Newmarket, Ontario, Canada, L3Y 2P7 Contact: Kim Robbins    905-235-5966    kim.yorkpci@gmail.com    Principal Investigator: Warren Cantor, MD          Sunnybrook Health Sciences Centre Recruiting Toronto, Ontario, Canada, M4N 3M5 Contact: Suneet Khurana    416-480-4520    suneet.khurana@sunnybrook.ca    Principal Investigator: Mina Madan, MD          St. Michael's Hospital Recruiting Toronto, Ontario, Canada, M5B 1W8 Contact: Brigita Zile    416-864-6060 ext 4130    zileb@smh.ca    Principal Investigator: John J Graham, MD          Toronto General Hospital, University Health Network Recruiting Toronto, Ontario, Canada, M5G 2C4 Contact: Nadia Asif    416-340-4800 ext 4969    nadia.asif@uhn.ca    Principal Investigator: Vladimir Dzavik, MD          Canada, Quebec Institut universitaire de cardiologie et de pneumologie de Quebec (Hopital Laval) Recruiting Quebec City, Quebec, Canada, G1V 4G5 Contact: Michele Jadin    418-656-8711 ext 3007    michele.jadin@criucpq.ulaval.ca    Principal Investigator: Olivier Bertrand, MD Collapse <<
  NCT00940823	Glaucoma	Not Applicable	Completed	-	United States, Indiana ... more >> Eugene and Marilyn Glick Eye Institute Indianapolis, Indiana, United States, 46202 United States, Tennessee Vanderbilt Eye Institute Nashville, Tennessee, United States, 37232 United States, Wisconsin Drs. Massaro and Kalenak Milwaukee, Wisconsin, United States, 53226 Canada, Ontario Credit ValleyEC Toronto, Ontario, Canada, L5L 1W8 Canada, Quebec Montreal Glaucoma Institute Montreal, Quebec, Canada, H1V 1G5 Chile Clinic of Las Condes Santiago, Chile Collapse <<
  NCT03499964	Urethral Stricture	Not Applicable	Recruiting	November 2024	United States, Arkansas ... more >> Arkansas Urology Recruiting Little Rock, Arkansas, United States, 72211 Contact: Katie O'Brien          Principal Investigator: Richard D'Anna, MD          Sub-Investigator: Keith Mooney, MD          Sub-Investigator: Edwin Diaz, MD          Sub-Investigator: Jeffrey Marotte, MD          Sub-Investigator: Megan Thomas, APRN          United States, Colorado Urology Associates, P.C. Recruiting Englewood, Colorado, United States, 80113 Contact: Lenden Neeper          Contact: Michelle Lexin          Principal Investigator: Barrett Cowan, MD          United States, Florida Advanced Urology Institute Recruiting Daytona Beach, Florida, United States, 32114 Contact: Jonelle Horsley          Principal Investigator: Jeffrey Dann, MD          United States, Maryland Chesapeake Urology Recruiting Hanover, Maryland, United States, 21076 Contact: Wendy Paxton          Principal Investigator: Kaiser Robertson, MD          Sub-Investigator: Robert Goldfarb, MD          Chesapeake Urology Research Recruiting Towson, Maryland, United States, 21204 Contact: Jacqueline Burmer          Principal Investigator: Richard Levin, MD          Sub-Investigator: Ronald Tutrone, MD          United States, Minnesota University of Minnesota Department of Urology Not yet recruiting Minneapolis, Minnesota, United States, 55445 Contact: Bethany Marlette          Principal Investigator: Sean Elliott, MD          United States, New Jersey Delaware Valley Urology Recruiting Voorhees, New Jersey, United States, 08043 Contact: Brianna Florentine          Principal Investigator: David Sussman, DO          United States, New York Western New York Urology Associates Recruiting Cheektowaga, New York, United States, 14225 Contact: Margaret Scott          Contact: Thomasina Smith          Principal Investigator: Kent Chevli, MD          Sub-Investigator: Peter Walter, MD          Columbia University Medical Center/New York-Presbyterian Hospital Not yet recruiting New York, New York, United States, 10032 Contact: Debduth Pijush          Principal Investigator: Steven Brandes, MD          Iris Cantor Men's Health Center Recruiting New York, New York, United States, 10065 Contact: Dominique Thomas          Principal Investigator: Alexis Te, MD          United States, Oregon Oregon Urology Institute Recruiting Springfield, Oregon, United States, 97477 Contact: Danna Cardenas          Principal Investigator: David DiMarco, MD          Sub-Investigator: Brian Mehlaff, MD          United States, South Carolina Carolina Urology Partners Recruiting West Columbia, South Carolina, United States, 29169 Contact: Pam Tims          Contact: Kristin Kennedy          Principal Investigator: Brian Willard, MD          Sub-Investigator: David Lamb, MD          Sub-Investigator: Keith Brightbill, MD          Sub-Investigator: Griffin Morrisson, MD          United States, Texas Urology San Antonio Recruiting San Antonio, Texas, United States, 78229 Contact: Jeannette Cruz          Principal Investigator: Christopher Cantrill, MD          Sub-Investigator: Daniel Saltzstein, MD          Sub-Investigator: Clayton Hudnall, MD          Sub-Investigator: Davie Talley, MD          United States, Virginia Urology of Virginia Recruiting Virginia Beach, Virginia, United States, 23462 Contact: Daniel Bekong          Principal Investigator: Ramon Virasoro, MD          Sub-Investigator: Jessica DeLong, MD          Sub-Investigator: Jeremy Tonkin, MD          Sub-Investigator: Kurt McCammon, MD          United States, Washington University of Washington Harborview Medical Center Recruiting Seattle, Washington, United States, 98104 Contact: Michael Donahue          Principal Investigator: Judith Hagedorn, MD          Sub-Investigator: Neils Johnsen, MD Collapse <<

• 更多
• 参考文献

• [1] Contreras JM, Rival YM, et al. Aminopyridazines as acetylcholinesterase inhibitors. J Med Chem. 1999 Feb 25;42(4):730-41.

  [2] Kan JP, Mouget-Goniot C, et al. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. Biochem Pharmacol. 1986 Mar 15;35(6):973-8.