CAS No.: 459-86-9
Mitoguazone/米托瓜酮 Catalog No. CSN29538
Synonyms: Methylglyoxal-bis(guanylhydrazone);MGBG;Methyl-GAG
Mitoguazone is a guanylhydrazone with potential antineoplastic activity. Mitoguazone competitively inhibits S-adenosyl-L-methionine decarboxylase (SAMD), an enzyme involved in the synthesis of polyamines, resulting in decreased proliferation of tumor cells, antimitochondrial effects, and p53-independent apoptosis. Polyamines, specifically spermine and spermidine, are essential for thymidine kinase production, DNA synthesis, and cell proliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 459-86-9 | 储存条件 |
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| 分子式 | C5H12N8 | 运输 | 蓝冰 | |
| 分子量 | 184.20 | 别名 | Methylglyoxal-bis(guanylhydrazone);MGBG;Methyl-GAG;MeGAG;methylG;MGGH;DRG0223;NSC32946;米托瓜酮 |
