CAS No.: 1314883-11-8
MMV390048 Catalog No. CSN19725
Synonyms: MMV-048
MMV390048 is an antimalarial compound belonging to the aminopyridine class for treating malaria. It is efficacious against all Plasmodium life cycle stages, apart from late hypnozoites in the liver.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02230579 Malaria Phase 1 Completed - South Africa ... more >> Cinical Pharmacology, University of Cape Town Cape Town, South Africa Collapse << NCT02783820 Malaria Phase 1 Completed - Australia ... more >> Q Pharm Clinics Herston, Australia, QLD 4006 Collapse << NCT02230579 - - Completed - - - 更多
- 参考文献
- [1] Sonopo MS, Pillay A, et al. Carbon-14 radiolabeling and tissue distribution evaluation of MMV390048. J Labelled Comp Radiopharm. 2016 Dec;59(14):680-688.
- [2] Paquet T, Le Manach C, et al. Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase. Sci Transl Med. 2017 Apr 26;9(387).
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1314883-11-8 | 储存条件 |
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| 分子式 | C18H14F3N3O2S | 运输 | 蓝冰 | |
| 分子量 | 393.38 | 别名 | MMV-048 |
