|苯甲酰磺胺|CsnPharm

CAS No.: 127-71-9

苯甲酰磺胺 Catalog No. CSN23227

Synonyms: 苯甲酰磺胺;N-Sulfanilylbenzamide;磺胺苯甲酰胺

Sulfabenzamide is a widely used chemical intermediate with antibacterial activity.

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400-920-2911

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技术信息

生物活性

描述Sulfabenzamide is a intermediate in the synthesis of organic and pharmaceutical. Sulfabenzamide metal complexes were active against Gram-positive and negative bacterial strains. Sulfabenzamide complexes exhibited related MIC values from 1.000 to 2.000 g ml-1^[1]. Sulfonamide compounds enhanced the avirulent Pseudomonas-induced cell death of Arabidopsis suspension cell cultures and increased disease resistance in Arabidopsis plants against both avirulent and virulent strains of the bacterium. In addition, although sulfonamides are known to be folate biosynthesis inhibitors, the application of folate did not restore the potentiation effects of the sulfonamides on pathogen-induced cell death^[2].
参考文献

[1] Rostamizadeh S, Daneshfar Z, Moghimi H. Synthesis of sulfamethoxazole and sulfabenzamide metal complexes; evaluation of their antibacterial activity. Eur J Med Chem. 2019;171:364‐371
[2] Noutoshi Y, Ikeda M, Saito T, Osada H, Shirasu K. Sulfonamides identified as plant immune-priming compounds in high-throughput chemical screening increase disease resistance in Arabidopsis thaliana. Front Plant Sci. 2012;3:245. Published 2012 Oct 31

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.6191 mL
- 18.0956 mL
- 36.1911 mL
- 5 mM
- 0.7238 mL
- 3.6191 mL
- 7.2382 mL
- 10 mM
- 0.3619 mL
- 1.8096 mL
- 3.6191 mL

技术信息

CAS号

127-71-9

储存条件

粉末: Keep in dark place,Inert atmosphere,Room temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C13H12N2O3S

运输

蓝冰

分子量

276.31

别名

苯甲酰磺胺;N-Sulfanilylbenzamide;磺胺苯甲酰胺

溶解度

DMSO	215.0 mg/mL (778.1 mM)
Water	insoluble

动物实验配方

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