|N-(4-((6,7-二甲氧基喹啉-4-基)氧基)苯基)-N-(4-氟苯基)环丙烷-1,1-二甲酰胺 (S)-2-羟基丁二酸盐|CsnPharm

CAS No.: 1140909-48-3

卡博替尼苹果酸盐 Catalog No. CSN16877

Synonyms: XL184 S-malate;BMS-907351 S-malate;Cabozantinib S-Malate

Cabozantinib S-malate is a VEGFR2 inhibitor with IC50 of 0.035 nM. It also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM-11.3 nM.

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

靶点 VEGFR2

IC50:0.035nM c-Met

IC50:1.3nM FLT3

IC50:11.3nM VEGFR1

IC50:12nM Tie-2

IC50:14.3nM 更多
描述Cabozantinib S-malate is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01703065	Adenocarcinoma of the Prostate... more >> Castration-resistant Prostate Cancer Recurrent Prostate Cancer Stage III Prostate Cancer Stage IV Prostate Cancer Collapse <<	Phase 2	Terminated(Closed 2017 for low... more >> accrual. Last data for primary outcome on 02Feb2015.) Collapse <<	-	United States, Washington ... more >> Seattle Cancer Care Alliance/University of Washington Seattle, Washington, United States, 98109 Collapse <<
NCT01703065	-	-	Terminated(Closed 2017 for low... more >> accrual. Last data for primary outcome on 02Feb2015.) Collapse <<	-	-
NCT03612232	Adrenocortical Carcinoma	Phase 2	Not yet recruiting	June 2022	Germany ... more >> University Hospital Würzburg Not yet recruiting Würzburg, Germany, 97080 Contact: Matthias Kroiss, MD, PhD +4993120139740 Kroiss_M@ukw.de Contact: Martin Fassnacht, MD +4993120139200 Fassnacht_M@ukw.de Collapse <<

更多
参考文献

[1] You WK, Sennino B, et al. VEGF and c-Met blockade amplify angiogenesis inhibition in pancreatic islet cancer. Cancer Res. 2011 Jul 15;71(14):4758-68.
[2] Torres KE, Zhu QS, et al. Activated MET is a molecular prognosticator and potential therapeutic target for malignant peripheral nerve sheath tumors. Clin Cancer Res. 2011 Jun 15;17(12):3943-55.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.5733 mL
- 7.8667 mL
- 15.7333 mL
- 5 mM
- 0.3147 mL
- 1.5733 mL
- 3.1467 mL
- 10 mM
- 0.1573 mL
- 0.7867 mL
- 1.5733 mL

技术信息

CAS号

1140909-48-3

储存条件

粉末: Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C32H30FN3O10

运输

蓝冰

分子量

635.59

别名

XL184 S-malate;BMS-907351 S-malate;Cabozantinib S-Malate;XL 184;BMS-907351;Cabozantinib malate;卡博替尼苹果酸盐

溶解度

DMSO	98.0 mg/mL (154.2 mM)
Water	Insoluble
Ethanol	Insoluble

动物实验配方

30% propylene glycol+5% Tween 80+65% water

15 mg/mL

suspension

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT01703065	Adenocarcinoma of the Prostate... more >> Castration-resistant Prostate Cancer Recurrent Prostate Cancer Stage III Prostate Cancer Stage IV Prostate Cancer Collapse <<	Phase 2	Terminated(Closed 2017 for low... more >> accrual. Last data for primary outcome on 02Feb2015.) Collapse <<	-	United States, Washington ... more >> Seattle Cancer Care Alliance/University of Washington Seattle, Washington, United States, 98109 Collapse <<
NCT01703065	-	-	Terminated(Closed 2017 for low... more >> accrual. Last data for primary outcome on 02Feb2015.) Collapse <<	-	-
NCT03612232	Adrenocortical Carcinoma	Phase 2	Not yet recruiting	June 2022	Germany ... more >> University Hospital Würzburg Not yet recruiting Würzburg, Germany, 97080 Contact: Matthias Kroiss, MD, PhD +4993120139740 Kroiss_M@ukw.de Contact: Martin Fassnacht, MD +4993120139200 Fassnacht_M@ukw.de Collapse <<
NCT01716715	Recurrent Fallopian Tube Carci... more >>noma Recurrent Ovarian Carcinoma Recurrent Primary Peritoneal Carcinoma Collapse <<	Phase 2	Active, not recruiting	-	-
NCT02761057	Stage III Renal Cell Cancer AJ... more >>CC v7 Stage IV Renal Cell Cancer AJCC v7 Type 1 Papillary Renal Cell Carcinoma Type 2 Papillary Renal Cell Carcinoma Unresectable Renal Cell Carcinoma Collapse <<	Phase 2	Suspended(Scheduled Interim Mo... more >>nitoring) Collapse <<	-	-
NCT01708954	Recurrent Non-Small Cell Lung ... more >>Carcinoma Stage IV Non-Small Cell Lung Cancer AJCC v7 Collapse <<	Phase 2	Active, not recruiting	March 17, 2020	-
NCT01835145	Recurrent Uveal Melanoma ... more >> Stage III Uveal Melanoma AJCC v7 Stage IIIA Uveal Melanoma AJCC v7 Stage IIIB Uveal Melanoma AJCC v7 Stage IIIC Uveal Melanoma AJCC v7 Stage IV Uveal Melanoma AJCC v7 Collapse <<	Phase 2	Completed	-	-
NCT03541902	Malignant Neoplasms of Urinary... more >> Tract Renal Cell Carcinoma Collapse <<	Phase 2	Recruiting	July 2020	United States, Texas ... more >> University of Texas MD Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact mcampbell3@mdanderson.org MD Anderson Katy Regional Care Center Recruiting Houston, Texas, United States, 77094 MD Anderson Sugarland Regional Care Center Recruiting Sugar Land, Texas, United States, 77478 Collapse <<
NCT03375320	Atypical Carcinoid Tumor ... more >> Carcinoid Tumor Digestive System Neuroendocrine Neoplasm Enterochromaffin Cell Serotonin-Producing Pancreatic Neuroendocrine Tumor Functional Pancreatic Neuroendocrine Tumor Intermediate Grade Lung Neuroendocrine Neoplasm Low Grade Lung Neuroendocrine Neoplasm Lung Atypical Carcinoid Tumor Lung Carcinoid Tumor Metastatic Digestive System Neuroendocrine Tumor G1 Neuroendocrine Neoplasm Nonfunctional Pancreatic Neuroendocrine Tumor Pancreatic Neuroendocrine Tumor Stage IIIA Digestive System Neuroendocrine Tumor AJCC v7 Stage IIIB Digestive System Neuroendocrine Tumor AJCC v7 Stage IV Digestive System Neuroendocrine Tumor AJCC v7 Collapse <<	Phase 3	Recruiting	January 1, 2021	-
NCT01812668	Adenocarcinoma of the Prostate... more >> Hormone-resistant Prostate Cancer Recurrent Prostate Cancer Stage IV Prostate Cancer Collapse <<	Not Applicable	Active, not recruiting	June 30, 2018	United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294-3280 United States, Michigan Barbara Ann Karmanos Cancer Institute Detroit, Michigan, United States, 48201 Henry Ford Hospital Detroit, Michigan, United States, 48202 United States, Ohio Ohio State University Columbus, Ohio, United States, 43210 Collapse <<
NCT03468985	c-MET Gene Amplification ... more >> MET Exon 14 Mutation Metastatic Lung Non-Squamous Non-Small Cell Carcinoma Recurrent Non-Squamous Non-Small Cell Lung Carcinoma RET/PTC Rearrangement ROS1 Gene Rearrangement Stage IV Non-Small Cell Lung Cancer AJCC v7 Collapse <<	Phase 2	Suspended(Other - Suspended wh... more >>ile redesign is developed) Collapse <<	December 31, 2021	-
NCT01708954	-	-	Active, not recruiting	-	-
NCT01866410	Recurrent Non-Small Cell Lung ... more >>Carcinoma Stage IV Non-Small Cell Lung Cancer AJCC v7 Collapse <<	Phase 2	Completed	-	United States, California ... more >> City of Hope Comprehensive Cancer Center Duarte, California, United States, 91010 USC / Norris Comprehensive Cancer Center Los Angeles, California, United States, 90033 University of California Davis Comprehensive Cancer Center Sacramento, California, United States, 95817 City of Hope South Pasadena South Pasadena, California, United States, 91030 United States, Michigan Wayne State University/Karmanos Cancer Institute Detroit, Michigan, United States, 48201 United States, Pennsylvania Penn State Milton S Hershey Medical Center Hershey, Pennsylvania, United States, 17033-0850 University of Pittsburgh Cancer Institute (UPCI) Pittsburgh, Pennsylvania, United States, 15232 Collapse <<
NCT01835158	Clear Cell Renal Cell Carcinom... more >>a Metastatic Renal Cell Cancer Stage III Renal Cell Cancer AJCC v7 Stage IV Renal Cell Cancer AJCC v7 Collapse <<	Phase 2	Active, not recruiting	-	-
NCT02496208	Bladder Small Cell Neuroendocr... more >>ine Carcinoma Clear Cell Renal Cell Carcinoma Infiltrating Bladder Urothelial Carcinoma Sarcomatoid Variant Infiltrating Bladder Urothelial Carcinoma, Plasmacytoid Variant Kidney Medullary Carcinoma Metastatic Malignant Neoplasm in the Bone Metastatic Penile Carcinoma Metastatic Renal Cell Carcinoma Renal Pelvis Urothelial Carcinoma Sarcomatoid Renal Cell Carcinoma Squamous Cell Carcinoma of the Penis Stage III Bladder Adenocarcinoma AJCC v6 and v7 Stage III Bladder Squamous Cell Carcinoma AJCC v6 and v7 Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 Stage III Penile Cancer AJCC v7 Stage III Renal Cell Cancer AJCC v7 Stage III Renal Pelvis Cancer AJCC v7 Stage III Ureter Cancer AJCC v7 Stage III Urethral Cancer AJCC v7 Stage IIIa Penile Cancer AJCC v7 Stage IIIb Penile Cancer AJCC v7 Stage IV Bladder Adenocarcinoma AJCC v7 Stage IV Bladder Squamous Cell Carcinoma AJCC v7 Stage IV Bladder Urothelial Carcinoma AJCC v7 Stage IV Penile Cancer AJCC v7 Stage IV Renal Cell Cancer AJCC v7 Stage IV Renal Pelvis Cancer AJCC v7 Stage IV Ureter Cancer AJCC v7 Stage IV Urethral Cancer AJCC v7 Ureter Urothelial Carcinoma Urethral Urothelial Carcinoma Collapse <<	Phase 1	Recruiting	-	United States, California ... more >> City of Hope Comprehensive Cancer Center Suspended Duarte, California, United States, 91010 Los Angeles County-USC Medical Center Suspended Los Angeles, California, United States, 90033 USC / Norris Comprehensive Cancer Center Suspended Los Angeles, California, United States, 90033 University of California Davis Comprehensive Cancer Center Recruiting Sacramento, California, United States, 95817 Contact: Site Public Contact 916-734-3089 Principal Investigator: Chong-Xian Pan United States, Maryland National Institutes of Health Clinical Center Recruiting Bethesda, Maryland, United States, 20892 Contact: Site Public Contact 800-411-1222 Principal Investigator: Andrea B. Apolo NCI - Center for Cancer Research Recruiting Bethesda, Maryland, United States, 20892 Contact: Site Public Contact 800-411-1222 Principal Investigator: Andrea B. Apolo United States, New Jersey Rutgers Cancer Institute of New Jersey Recruiting New Brunswick, New Jersey, United States, 08903 Contact: Site Public Contact 732-235-8675 Principal Investigator: Biren Saraiya United States, Ohio Ohio State University Comprehensive Cancer Center Recruiting Columbus, Ohio, United States, 43210 Contact: Site Public Contact 800-293-5066 Jamesline@osumc.edu Principal Investigator: Amir Mortazavi Collapse <<
NCT01935934	Endometrial Adenosquamous Carc... more >>inoma Endometrial Clear Cell Adenocarcinoma Endometrial Mixed Adenocarcinoma Endometrial Serous Adenocarcinoma Metastatic Endometrioid Adenocarcinoma Recurrent Uterine Corpus Carcinoma Stage IV Uterine Corpus Cancer AJCC v7 Stage IVA Uterine Corpus Cancer AJCC v7 Stage IVB Uterine Corpus Cancer AJCC v7 Uterine Corpus Carcinosarcoma Collapse <<	Phase 2	Suspended(Other - Accrual goal... more >> met; amendment in review to add new cohort) Collapse <<	-	United States, California ... more >> City of Hope Comprehensive Cancer Center Duarte, California, United States, 91010 USC / Norris Comprehensive Cancer Center Los Angeles, California, United States, 90033 University of California Davis Comprehensive Cancer Center Sacramento, California, United States, 95817 City of Hope South Pasadena South Pasadena, California, United States, 91030 United States, Illinois University of Chicago Comprehensive Cancer Center Chicago, Illinois, United States, 60637 Decatur Memorial Hospital Decatur, Illinois, United States, 62526 NorthShore University HealthSystem-Evanston Hospital Evanston, Illinois, United States, 60201 Southern Illinois University School of Medicine Springfield, Illinois, United States, 62702 United States, Indiana Indiana University/Melvin and Bren Simon Cancer Center Indianapolis, Indiana, United States, 46202 United States, Michigan University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan, United States, 48109 Wayne State University/Karmanos Cancer Institute Detroit, Michigan, United States, 48201 United States, Pennsylvania Fox Chase Cancer Center Philadelphia, Pennsylvania, United States, 19111 UPMC-Magee Womens Hospital Pittsburgh, Pennsylvania, United States, 15213 Canada, Alberta Tom Baker Cancer Centre Calgary, Alberta, Canada, T2N 4N2 Cross Cancer Institute Edmonton, Alberta, Canada, T6G 1Z2 Canada, Ontario Juravinski Cancer Centre at Hamilton Health Sciences Hamilton, Ontario, Canada, L8V 5C2 Kingston Health Sciences Centre Kingston, Ontario, Canada, K7L 2V7 London Regional Cancer Program London, Ontario, Canada, N6A 4L6 Ottawa Hospital and Cancer Center-General Campus Ottawa, Ontario, Canada, K1H 8L6 University Health Network-Princess Margaret Hospital Toronto, Ontario, Canada, M5G 2M9 Collapse <<
NCT01811212	Poorly Differentiated Thyroid ... more >>Gland Carcinoma Recurrent Thyroid Gland Carcinoma Stage I Thyroid Gland Follicular Carcinoma Stage I Thyroid Gland Papillary Carcinoma Stage II Thyroid Gland Follicular Carcinoma Stage II Thyroid Gland Papillary Carcinoma Stage III Thyroid Gland Follicular Carcinoma Stage III Thyroid Gland Papillary Carcinoma Stage IVA Thyroid Gland Follicular Carcinoma Stage IVA Thyroid Gland Papillary Carcinoma Stage IVB Thyroid Gland Follicular Carcinoma Stage IVB Thyroid Gland Papillary Carcinoma Stage IVC Thyroid Gland Follicular Carcinoma Stage IVC Thyroid Gland Papillary Carcinoma Tall Cell Variant Thyroid Gland Papillary Carcinoma Thyroid Gland Oncocytic Follicular Carcinoma Collapse <<	Phase 2	Completed	-	United States, District of Col... more >>umbia MedStar Georgetown University Hospital Washington, District of Columbia, United States, 20007 United States, Florida Mayo Clinic in Florida Jacksonville, Florida, United States, 32224-9980 United States, Illinois University of Chicago Comprehensive Cancer Center Chicago, Illinois, United States, 60637 United States, Massachusetts Massachusetts General Hospital Cancer Center Boston, Massachusetts, United States, 02114 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 United States, Ohio Ohio State University Comprehensive Cancer Center Columbus, Ohio, United States, 43210 United States, Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse <<
NCT01811212	-	-	Completed	-	-
NCT02243605	Metastatic Ewing Sarcoma ... more >> Metastatic Osteosarcoma Recurrent Ewing Sarcoma Recurrent Osteosarcoma Stage III Osteosarcoma AJCC v7 Stage IV Osteosarcoma AJCC v7 Stage IVA Osteosarcoma AJCC v7 Stage IVB Osteosarcoma AJCC v7 Unresectable Ewing Sarcoma Unresectable Osteosarcoma Collapse <<	Phase 2	Recruiting	-	France ... more >> Institut Bergonie Cancer Center Recruiting Bordeaux, France, 33076 Contact: Antoine Italiano b.lortal@bordeaux.unicancer.fr Principal Investigator: Antoine Italiano Centre Georges-Francois Leclerc Recruiting Dijon, France, 21079 Contact: Nicolas Isambert 33-3-80-73-75-06 nisambert@cgfl.fr Principal Investigator: Nicolas Isambert Centre Oscar Lambert Recruiting Lille, France, 59020 Contact: Nicolas P. Penel 33-3-20-29-59-20 n-penel@o-lambret.fr Principal Investigator: Nicolas P. Penel Centre Leon Berard Recruiting Lyon, France, 69373 Contact: Jean-Yves Blay 33-4-78-78-28-28 jean-yves.blay@lyon.unicancer.fr Principal Investigator: Jean-Yves Blay Hopital De La Timone Recruiting Marseille, France, 13385 Contact: Florence Duffaud 33-4-91-38-74-14 Florence.duffaud@ap-hm.fr Principal Investigator: Florence Duffaud Centre Antoine Lacassagne Recruiting Nice, France, 06189 Contact: Antoine Thyss 33-4-92-03-14-97 antoine.thyss@nice.unicancer.fr Principal Investigator: Antoine Thyss Institut Curie Paris Recruiting Paris, France, 75005 Contact: Sophie Piperno-Neumann 33-1-44-32-46-80 sophie.piperno-neumann@curie.net Principal Investigator: Sophie Piperno-Neumann Institut de Cancerologie de l'Ouest-Rene Gauducheau Recruiting Saint Herblain, France, 44805 Contact: Emmanuelle Bompas 33-2-40-67-99-39 emmanuelle.bompas@ico.unicancer.fr Principal Investigator: Emmanuelle Bompas CHRU Strasbourg - Hospital Civil Recruiting Strasbourg, France, 67091 Contact: Natacha Entz-Werle 33-3-88-12-80-97 Natacha.entz-werle@chru-strasbourg.fr Principal Investigator: Natacha Entz-Werle Center Claudius Regaud Recruiting Toulouse, France, 31052 Contact: Christine Chevreau 33-5-61-42-42-42 chevreau.christine@iuct-oncopole.fr Principal Investigator: Christine Chevreau Gustave Roussy Recruiting Villejuif, France, 94805 Contact: Olivier Mir 33-1-42-11-43-16 olivier.mir@gustaveroussy.fr Principal Investigator: Olivier Mir Collapse <<
NCT01709435	Childhood Solid Neoplasm ... more >> Childhood Thyroid Gland Medullary Carcinoma Recurrent Childhood Central Nervous System Neoplasm Recurrent Malignant Solid Neoplasm Recurrent Melanoma Recurrent Thyroid Gland Carcinoma Refractory Malignant Solid Neoplasm Collapse <<	Phase 1	Active, not recruiting	-	-
NCT02315430	Fallopian Tube Clear Cell Aden... more >>ocarcinoma Ovarian Clear Cell Adenocarcinoma Recurrent Fallopian Tube Carcinoma Recurrent Ovarian Carcinoma Recurrent Primary Peritoneal Carcinoma Collapse <<	Phase 2	Active, not recruiting	-	-
NCT01835184	Recurrent Melanoma ... more >> Stage IIIA Melanoma Stage IIIB Melanoma Stage IIIC Melanoma Stage IV Melanoma Unspecified Adult Solid Tumor, Protocol Specific Collapse <<	Phase 1	Terminated	-	United States, Georgia ... more >> Emory University/Winship Cancer Institute Atlanta, Georgia, United States, 30322 United States, Massachusetts Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, Virginia Virginia Commonwealth University Richmond, Virginia, United States, 23298 Collapse <<
NCT02867592	Adrenal Cortex Carcinoma ... more >> Alveolar Soft Part Sarcoma Central Nervous System Neoplasm Childhood Clear Cell Sarcoma of Soft Parts Clear Cell Sarcoma of Soft Tissue Ewing Sarcoma Hepatoblastoma Hepatocellular Carcinoma MITF Positive Osteosarcoma Recurrent Adrenal Cortex Carcinoma Recurrent Alveolar Soft Part Sarcoma Recurrent Ewing Sarcoma Recurrent Hepatoblastoma Recurrent Hepatocellular Carcinoma Recurrent Malignant Central Nervous System Neoplasm Recurrent Malignant Solid Neoplasm Recurrent Osteosarcoma Recurrent Renal Cell Carcinoma Recurrent Rhabdomyosarcoma Recurrent Soft Tissue Sarcoma Recurrent Soft Tissue Sarcoma, Excluding Rhabdomyosarcoma Recurrent Thyroid Gland Medullary Carcinoma Refractory Ewing Sarcoma Refractory Malignant Central Nervous System Neoplasm Refractory Malignant Solid Neoplasm Refractory Osteosarcoma Refractory Rhabdomyosarcoma Refractory Soft Tissue Sarcoma Refractory Soft Tissue Sarcoma, Excluding Rhabdomyosarcoma Renal Cell Carcinoma Rhabdomyosarcoma Soft Tissue Sarcoma, Excluding Rhabdomyosarcoma Solid Neoplasm Thyroid Gland Medullary Carcinoma Wilms Tumor Collapse <<	Phase 2	Recruiting	June 30, 2021	-
NCT01822522	Advanced Malignant Solid Neopl... more >>asm HIV Infection Metastatic Malignant Solid Neoplasm Recurrent Malignant Solid Neoplasm Unresectable Solid Neoplasm Collapse <<	Phase 1	Recruiting	-	United States, California ... more >> UC San Diego Moores Cancer Center Recruiting La Jolla, California, United States, 92093 Contact: Missak Haigentz aecc@aecom.yu.edu Principal Investigator: Missak Haigentz UCLA Center for Clinical AIDS Research and Education Recruiting Los Angeles, California, United States, 90035 Contact: Missak Haigentz aecc@aecom.yu.edu Principal Investigator: Missak Haigentz UCLA / Jonsson Comprehensive Cancer Center Recruiting Los Angeles, California, United States, 90095 Contact: Ronald T. Mitsuyasu 888-798-0719 rmitsuya@mednet.ucla.edu Principal Investigator: Ronald T. Mitsuyasu University of California San Diego Recruiting San Diego, California, United States, 92103 Contact: William Wachsman 858-552-8585 ext 2628 wwachsman@ucsd.edu Principal Investigator: William Wachsman United States, Hawaii University of Hawaii Cancer Center Active, not recruiting Honolulu, Hawaii, United States, 96813 United States, Louisiana Louisiana State University Recruiting Lafayette, Louisiana, United States, 70503 Contact: Thomas M. Reske 504-568-2428 emede1@lsuhsc.edu Principal Investigator: Thomas M. Reske United States, Maryland Johns Hopkins University/Sidney Kimmel Cancer Center Recruiting Baltimore, Maryland, United States, 21287 Contact: Richard F. Ambinder 410-955-8804 jhcccro@jhmi.edu Principal Investigator: Richard F. Ambinder United States, Massachusetts Boston Medical Center Recruiting Boston, Massachusetts, United States, 02118 Contact: Timothy P. Cooley 617-638-8265 timothy.cooley@bmc.org Principal Investigator: Timothy P. Cooley United States, Missouri Siteman Cancer Center at Washington University Recruiting Saint Louis, Missouri, United States, 63110 Contact: Missak Haigentz aecc@aecom.yu.edu Principal Investigator: Missak Haigentz Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Lee Ratner 800-600-3606 info@siteman.wustl.edu Principal Investigator: Lee Ratner United States, New York Montefiore Medical Center-Einstein Campus Withdrawn Bronx, New York, United States, 10461 Montefiore Medical Center-Weiler Hospital Recruiting Bronx, New York, United States, 10461 Contact: Missak Haigentz 718-920-4826 mhaigent@montefiore.org Principal Investigator: Missak Haigentz Montefiore Medical Center - Moses Campus Recruiting Bronx, New York, United States, 10467 Contact: Missak Haigentz aecc@aecom.yu.edu Principal Investigator: Missak Haigentz United States, Ohio Ohio State University Comprehensive Cancer Center Recruiting Columbus, Ohio, United States, 43210 Contact: Robert A. Baiocchi 614-293-3196 Jamesline@osumc.edu Principal Investigator: Robert A. Baiocchi United States, Texas Thomas Street Clinic Recruiting Houston, Texas, United States, 77009 Contact: Missak Haigentz aecc@aecom.yu.edu Principal Investigator: Missak Haigentz Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: Elizabeth Y. Chiao 713-794-8666 echiao@bcm.edu Principal Investigator: Elizabeth Y. Chiao Ben Taub General Hospital Recruiting Houston, Texas, United States, 77030 Contact: Elizabeth Y. Chiao 713-794-8666 echiao@bcm.edu Principal Investigator: Elizabeth Y. Chiao United States, Washington Virginia Mason Medical Center Recruiting Seattle, Washington, United States, 98101 Contact: David M. Aboulafia 800-354-9527 vmmc.cancer_clinical_research@VirginiaMason.org Principal Investigator: David M. Aboulafia Harborview Medical Center Recruiting Seattle, Washington, United States, 98104 Contact: Missak Haigentz aecc@aecom.yu.edu Principal Investigator: Missak Haigentz Fred Hutchinson Cancer Research Center Recruiting Seattle, Washington, United States, 98109 Contact: Corey Casper 800-422-6237 ccasper@fhcrc.org Principal Investigator: Corey Casper Collapse <<

靶点	Description	IC50
VEGFR2		IC50:0.035nM
c-Met		IC50:1.3nM
FLT3		IC50:11.3nM
VEGFR1		IC50:12nM
Tie-2		IC50:14.3nM
c-Kit		IC50:4.6nM
c-RET		IC50:4nM
FLT4		IC50:6nM
Axl		IC50:7nM

卡博替尼苹果酸盐 Catalog No. CSN16877

靶点选择性

请登录您的专属账户

确认信息