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CAS No.: 524722-52-9
Synonyms: ZD6474 hydrochloride;ZD6474 HCl
Vandetanib HCl specially inhibits VEGFR2 with IC50 of 40 nM.
生物活性
靶点 | VEGFR2 IC50:40nM |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT02638428 | Relapsed Pediatric Solid Tumor... more >> Refractory Pediatric Solid Tumor Relapsed Pediatric AML Refractory Pediatric AML Collapse << | Phase 2 | Recruiting | December 2023 | Korea, Republic of ... more >> Samsung Medical Center Recruiting Seoul, Korea, Republic of Contact: Ki Woong Sung 82-2-3410-3529 kwsped@skku.edu Principal Investigator: Ki Woong Sung Collapse << |
NCT02013089 | Gastrointestinal Cancers | Not Applicable | Unknown | December 2017 | China, Guangdong ... more >> Gastrointestinal Hospital, Sun Yat-sen University Recruiting Guangzhou, Guangdong, China, 510655 Contact: Yanghong Deng, PhD 008613925106525 13925106525@163.com Principal Investigator: Yanhong Deng, PhD Collapse << |
NCT02239952 | Cancer High-g... more >>rade Glioma Collapse << | Not Applicable | Recruiting | January 2019 | Netherlands ... more >> VU University Medical Center Recruiting Amsterdam, Noord-Holland, Netherlands, 1081 HV Contact: H.M.W Verheul, MD, PhD +31 (0)20 4444321 h.verheul@vumc.nl Collapse << |
实验方案
技术信息
CAS号 | 524722-52-9 | 储存条件 |
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分子式 | C22H25BrClFN4O2 | 运输 | 蓝冰 | |
分子量 | 511.81 | 别名 | ZD6474 hydrochloride;ZD6474 HCl |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02638428 | Relapsed Pediatric Solid Tumor... more >> Refractory Pediatric Solid Tumor Relapsed Pediatric AML Refractory Pediatric AML Collapse << | Phase 2 | Recruiting | December 2023 | Korea, Republic of ... more >> Samsung Medical Center Recruiting Seoul, Korea, Republic of Contact: Ki Woong Sung 82-2-3410-3529 kwsped@skku.edu Principal Investigator: Ki Woong Sung Collapse << |
NCT02013089 | Gastrointestinal Cancers | Not Applicable | Unknown | December 2017 | China, Guangdong ... more >> Gastrointestinal Hospital, Sun Yat-sen University Recruiting Guangzhou, Guangdong, China, 510655 Contact: Yanghong Deng, PhD 008613925106525 13925106525@163.com Principal Investigator: Yanhong Deng, PhD Collapse << |
NCT02239952 | Cancer High-g... more >>rade Glioma Collapse << | Not Applicable | Recruiting | January 2019 | Netherlands ... more >> VU University Medical Center Recruiting Amsterdam, Noord-Holland, Netherlands, 1081 HV Contact: H.M.W Verheul, MD, PhD +31 (0)20 4444321 h.verheul@vumc.nl Collapse << |
NCT01191892 | Bladder Cancer ... more >> Transitional Cell Cancer of the Renal Pelvis and Ureter Ureter Cancer Urethral Cancer Collapse << | Phase 2 | Unknown | December 2014 | United Kingdom ... more >> Beatson West of Scotland Cancer Centre Recruiting Glasgow, Scotland, United Kingdom, G12 0YN Contact: Contact Person 44-141-301-7095 Rob.Jones@ggc.scot.nhs.uk Wales Cancer Trials Unit Recruiting Cardiff, Wales, United Kingdom, CF11 9LJ Contact: Contact Person 44-29-2019-6800 Ayr Hospital Recruiting Ayr, United Kingdom, KA66DX Contact: Margaret McKernan 01563 825749 margaret.mckernan@aaaht.scot.nhs.uk Principal Investigator: Jawaher Ansari Royal Bournemouth General Hospital Recruiting Bournemouth, United Kingdom, BH7 7DW Contact: Susannah Brock susannah.brock@poole.nhs.uk Principal Investigator: Susannah Brock Queens Hospital Recruiting Burton upon Trent, United Kingdom, DE13 0RB Contact: Pugazhenthi Pattu 01332 340131 pugazhenthi.pattu@nhs.net Principal Investigator: Pugazhenthi Pattu Velindre Hospital Recruiting City and County of Cardiff, United Kingdom, CF142TL Contact: Dr Lester, Jason 44-2920 196159 jason.lester2@wales.nhs.uk Principal Investigator: Jason Lester Western General Hospital Recruiting Edinburgh, United Kingdom, EH4 2XU Contact: Duncan McLaren duncan.mclaren@luht.scot.nhs.uk Principal Investigator: Duncan McLaren Calderdale Royal Infirmary Recruiting Halifax, United Kingdom, HX30PW Contact: Lisa Gledhill 01484 342925 lisa.gledhill@cht.nhs.uk Principal Investigator: Ursula Hofmann Huddersfield Royal Infirmary Recruiting Huddersfield, United Kingdom, HD3 3EA Contact: Uschi Hofmann 0484 847299 uschi.hofmann@cht.nhs.uk Principal Investigator: Uschi Hofmann The Royal Lancaster Infirmary Recruiting Lancaster, United Kingdom, LA1 4RP Contact: Alison Birtle 01524 583219 alison.birtle@lhtr.nhs.uk Principal Investigator: Alison Birtle St. James's University Hospital Recruiting Leeds, United Kingdom, LS9 7TF Contact: Satinder Jagdev 0113 2067645 satinder.jagdev@leedsth.nhs.uk Principal Investigator: Satinder Jagdev The Royal Free Hospital Not yet recruiting London, United Kingdom, NW3 2QG Principal Investigator: Maria Vilarino-Varela St Marys Hospital Not yet recruiting London, United Kingdom, W21NY Contact: Gillian Hornzee Gillian.Hornzee@imperial.nhs.uk Principal Investigator: Simon Stewart Charing Cross Hospital Not yet recruiting London, United Kingdom, W68RF Contact: Simon Stewart simon.stewart@imperial.nhs.uk Principal Investigator: Simon Stewart Christie Hospital Recruiting Manchester, United Kingdom, M20 4BX Contact: Tony Eliott 01619187214 tony.eliott@christie.nhs.uk Principal Investigator: Tony Eliott Mount Vernon Hospital Recruiting Northwood Middlesex, United Kingdom, HA6 2RN Contact: Peter Hoskin 01923 844533 peter.hoskin@nhs.net Principal Investigator: Peter Hoskin Churchill Hospital Recruiting Oxford, United Kingdom, OX37LJ Contact: Georgina Rogers patpandrewprotheroe@oncology.ox.ac.uk Principal Investigator: Andrew Protheroe Weston Park Hospital Recruiting Sheffield, United Kingdom, S102SJ Contact: Linda Evans 0114 226500 linda.evans@sth.nhs.uk Principal Investigator: Linda Evans Southampton General Hospital Recruiting Southampton, United Kingdom, S016 6YD Contact: Simon Crabb s.j.crabb@southampton.ac.uk Principal Investigator: Simon Crabb Royal Surrey County Hospital Recruiting Surrey, United Kingdom, GU27XX Contact: Katie Wood 01483 571122 katiewood@nhs.net Principal Investigator: Katie Wood The Royal Marsden Hospital Recruiting Surrey, United Kingdom, KT2 7QB Contact: Robert Huddart 020 8661 3457 robert.huddart@icr.ac.uk Principal Investigator: Robert Huddart Collapse << |
NCT00364351 | - | - | Completed | - | - |
NCT00364351 | Non Small Cell Lung Cancer | Phase 3 | Completed | - | - |
靶点 | Description | IC50 |
---|---|---|
VEGFR2 | IC50:40nM |
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