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CAS No.: 1226056-71-8
Synonyms: Tzv
Thiazovivin is a ROCK inhibitor with IC50 of 0.5 μM in a cell-free assay, promotes hESC survival after single-cell dissociation.
生物活性
靶点 | ROCK IC50:0.5μM |
动物研究 | |
剂量 | Rat: 1 mg/kg - 30 mg/kg[3] (p.o.) |
给药途径 | p.o. |
实验方案
技术信息
CAS号 | 1226056-71-8 | 储存条件 |
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分子式 | C15H13N5OS | 运输 | 蓝冰 | |||||||||||||
分子量 | 311.36 | 别名 | Tzv | |||||||||||||
溶解度 |
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动物实验配方 |
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Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
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HSMCs | 1 μM | Function Assay | 2 h | reverses AngII-induced MYPT1 phosphorylation | 24965170 |
SCU-i10 hiPSCs | 0-20 μM | Growth Inhibition Assay | 24 h | significantly modulates single-cell plating efficiency and promote NCM growth | 25077932 |
靶点 | Description | IC50 |
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ROCK | IC50:0.5μM |
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