生物活性

• 描述Naphazoline is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride, it is a sympathomimetic agent with marked alpha adrenergic activity.
• 临床研究

• NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
  NCT00536367	-	-	Completed	-	United States, Ohio ... more >> The Ohio State University Medical Center Columbus, Ohio, United States, 43210 Collapse <<
  NCT03077308	-	-	Recruiting	July 31, 2019	United States, Colorado ... more >> University of Colorado Denver Recruiting Denver, Colorado, United States, 80045-2571 Contact: Gina VanderVeen    720-777-5514    Gina.VanderVeen@childrenscolorado.org    Principal Investigator: Tim Benke, MD, PhD          United States, Massachusetts Boston Children's Hospital Recruiting Boston, Massachusetts, United States, 02115-5724 Contact: Mustafa Sahin, MD, PhD    617-355-8994    mustafa.sahin@childrens.harvard.edu    Contact: Lindsay Swanson    617-355-8994    lindsay.swanson@childrens.harvard.edu    United States, New York University of Rochester Recruiting Rochester, New York, United States, 14627-0140 Contact: To be named          Principal Investigator: Alex Paciorkowski, MD, PhD          Sub-Investigator: Laurie Seltzer, MD          United States, Ohio Cincinnati Children's Hospital Recruiting Cincinnati, Ohio, United States, 45229 Contact: Max Mays    513-803-7935    Maxwell.Mays@cchmc.org    Principal Investigator: Shannon Standridge, DO          United States, Pennsylvania Children's Hospital of Philadelphia Recruiting Philadelphia, Pennsylvania, United States, 19104-4318 Contact: Casey Gorman    267-426-5171    GormanC@email.chop.edu    Principal Investigator: Eric Marsh, MD, PhD          United States, Tennessee Vanderbilt University Recruiting Nashville, Tennessee, United States, 37212 Contact: Nicole Thompson    615-343-4586    Nicole.i.thompson@vanderbilt.edu    Principal Investigator: Sar Peters, PhD          Sub-Investigator: Cary Fu, MD Collapse <<
  NCT02433080	Endometrial Neoplasms	Phase 2	Completed	-	United Kingdom ... more >> Barts Health NHS Trust London, Greater London, United Kingdom, E1 1BB University College London Hospital NHS Trust London, Greater London, United Kingdom, NW1 3AD Collapse <<

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• 参考文献

• [1] Imani-Nabiyyi A, Sorouraddin MH. Determination of naphazoline hydrochloride in biological and pharmaceutical samples by a quantum dot-assisted chemiluminescence system using response-surface methodology. Luminescence. 2014 Dec;29(8):994-1002.

  [2] Nagane Y, Utsugisawa K, et al. Topical naphazoline in the treatment of myasthenic blepharoptosis. Muscle Nerve. 2011 Jul;44(1):41-4.