CAS No.: 865466-24-6
Narlaprevir/那拉匹韦 Catalog No. CSN18498
Synonyms: SCH 900518;那拉匹韦
Narlaprevir is a potent, selective, orally bioavailable NS3 protease inhibitor (Ki=6 nM; EC90=40 nM).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00797745 Hepatitis C, Chronic Phase 2 Completed - - NCT01081158 Hepatitis C, Chronic Phase 1 Completed - - NCT03537404 Healthy Phase 1 Completed - Russian Federation ... more >> Clinic "Bessalar" JSC Moscow, Russian Federation Collapse << - 更多
- 参考文献
- [1] Zhu J, Li Y, et al. Insight into the structural requirements of narlaprevir-type inhibitors of NS3/NS4A protease based on HQSAR and molecular field analyses. Comb Chem High Throughput Screen. 2012 Jul;15(6):439-50.
- [2] Ashok A, Frank B, et al. Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor. ACS Med. Chem. Lett., 2010, 1 (2), pp 64–69
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 865466-24-6 | 储存条件 |
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| 分子式 | C36H61N5O7S | 运输 | 蓝冰 | |
| 分子量 | 707.96 | 别名 | SCH 900518;那拉匹韦 |
